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0142106411
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Direct synthesis of 2-arylbenzothiazoles or 2-arylbenzimidazoles from corresponding aromatic aldehydes and 2-aminothiophenols or 1,2-phenylenediamines in the presence of a Lewis acid or activated carbon under an oxygen atmosphere has been reported. In our case, however, neither additives nor a complete oxygen atmosphere was required for the oxidation. See: (a) Kawashita, Y.; Nakamichi, N.; Kawabata, H.; Hayashi, M. Org. Lett. 2003, 5, 3713-3715.
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33746331849
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note
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When only 2-aminothiophenol was stirred for 20 min under an air atmosphere at 100 °C in DMF, a substantial amount of decomposition products (a disulfide compound and so on) was observed by TLC.
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