Oral triiodothyronine for the prevention of thyroid hormone reduction in adult valvular cardiac surgery

Brazilian Journal of Medical and Biological Research

Volumn 39, Issue 7, 2006, Pages 969-978

  Magalhaes A P A ^a,c   Gus, M ^b   Silva, L B ^c   Schaan, Beatriz D ^a  

^a INSTITUTO DE CARDIOLOGIA DO RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c Santa Casa Complexo Hospitalar   (Brazil)

Author keywords

Cardiac surgery; Heart valve disease; Non thyroidal illness syndrome; Postoperative period

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HEPARIN; LIOTHYRONINE; LIOTHYRONINE SODIUM; PLACEBO; THYROTROPIN; THYROXINE;

ADULT; AORTA CLAMPING; ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HEART VALVE SURGERY; HEMODYNAMIC MONITORING; HUMAN; HYPOTHYROIDISM; LIOTHYRONINE BLOOD LEVEL; MALE; POSTOPERATIVE PERIOD; PREOPERATIVE CARE; PRIMARY PREVENTION; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; VALVULAR HEART DISEASE;

EID: 33746324266     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2006000700015     Document Type: Article

References (26)

1. De Groot LJ. Dangerous dogmas in medicine: the nonthyroidal illness syndrome. J Clin Endocrinol Metab 1999; 84: 151-164.
2. Cerillo AG, Bevilacqua S, Storti S, Mariani M, Kallushi E, Ripoli A, et al. Free triiodothyronine: a novel predictor of postoperative atrial fibrillation. Eur J Cardiothorac Surg 2003; 24: 487-492.
3. Holland FW, Brown Jr PS, Weintraub BD, Clark RE. Cardiopulmonary bypass and thyroid function: a "euthyroid sick syndrome". Ann Thorac Surg 1991; 52: 46-50.
4. Sabatino L, Cerillo AG, Ripoli A, Pilo A, Glauber M, lervasi G. Is the low tri-iodothyronine state a crucial factor in determining the outcome of coronary artery bypass patients? Evidence from a clinical pilot study. J Endocrinol 2002; 175: 577-586.
5. Klein I, Ojamaa K. Thyroid hormone and the cardiovascular system. N Engl J Med 2001; 344: 501-509.
6. Iervasi G, Pingitore A, Landi P, Raciti M, Ripoli A, Scarlattini M, et al. Low-T3 syndrome: a strong prognostic predictor of death in patients with heart disease. Circulation 2003; 107: 708-713.
7. Friberg L, Drvota V, Bjelak AH, Eggertsen G, Ahnve S. Association between increased levels of reverse triiodothyronine and mortality after acute myocardial infarction. Am J Med 2001; 111: 699-703.
8. Novitzky D, Cooper DK, Swanepoel A. Inotropic effect of triiodothyronine (T3) in low cardiac output following cardioplegic arrest and cardiopulmonary bypass: an initial experience in patients undergoing open heart surgery. Eur J Cardiothorac Surg 1989; 3: 140-145.
9. Klemperer JD, Klein I, Gomez M, Helm RE, Ojamaa K, Thomas SJ, et al. Thyroid hormone treatment after coronary-artery bypass surgery. N Engl J Med 1995; 333: 1522-1527.
10. Klemperer JD, Klein IL, Qjamaa K, Helm RE, Gomez M, Isom OW, et al. Triiodothyronine therapy lowers the incidence of atrial fibrillation after cardiac operations. Ann Thorac Surg 1996; 61: 1323-1327.
11. Bennett-Guerrero E, Jimenez JL, White WD, D'Amico EB, Baldwin BI, Schwinn DA, Cardiovascular effects of intravenous triiodothyronine in patients undergoing coronary artery bypass graft surgery. A randomized, double-blind, placebo-controlled trial. Duke T3 study group. JAMA 1996; 275: 687-692.
12. Mullis-Jansson SL, Argenziano, M, Corwin S, Homma S, Weinberg AD, Williams M, et al. A randomized double-blind study of the effect of triiodothyronine on cardiac function and morbidity after coronary bypass surgery. J Thorac Cardiovasc Surg 1999; 117: 1128-1134.
13. Cimochowski GE, Harostock MD, Foldes PJ. Minimal operative mortality in patients undergoing coronary artery bypass with significant left ventricular dysfunction by maximization of metabolic and mechanical support. J Thorac Cardiovasc Surg 1997; 113: 655-664.
14. Novitzky D, Fontanet H, Snyder M, Coblio N, Smith D, Parsonnet V. Impact of triiodothyronine on the survival of high-risk patients undergoing open heart surgery. Cardiology 1996; 87: 509-515.
15. Bettendorf M, Schmidt KG, Grulich-Henn J, Ulmer HE, Heinrich UE. Tri-iodothyronine treatment in children after cardiac surgery: a double-blind, randomised, placebo-controlled study. Lancet 2000; 356: 529-534.
16. Chowdhury D, Qjamaa K, Parnell VA, McMahon C, Sison CP, Klein I. A prospective randomized clinical study of thyroid hormone treatment after operations for complex congenital heart disease. J Thorac Cardiovasc Surg 2001; 122: 1023-1025.
17. Dimmick S, Badawi N, Randell T. Thyroid hormone supplementation for the prevention of morbidity and mortality in infants undergoing cardiac surgery. Cochrane Database Syst Rev 2004; CD004220.
18. Sirlak M, Yazicioglu L, Inan MB, Eryilmaz S, Tasoz R, Aral A, et al. Oral thyroid hormone pretreatment in left ventricular dysfunction. Eur J Cardiothorac Surg 2004; 26: 720-725.
19. Jekel JF, Elmore JG, Katz DL. Epidemiologia, bioestatística e medicina preventiva. Porto Alegre: Artmed, 2002; 178-191.
20. Arem R, Wiener GJ, Kaplan SG, Kim HS, Reichlin S, Kaplan MM. Reduced tissue thyroid hormone levels in fatal illness. Metabolism 1993; 42: 1102-1108.
21. Bremner WF, Taylor KM, Baird S, Thomson JE, Thomson JA, Ratcliffe JG, et al. Hypothalamo-pituitary-thyroid axis function during cardiopulmonary bypass. J Thorac Cardiovasc Surg 1978; 75: 392-399.
22. Blake NG, Eckland DJ, Foster OJ, Lightman SL. Inhibition of hypothalamic thyrotropin-releasing hormone messenger ribonucleic acid during food deprivation. Endocrinology 1991; 129: 2714-2718.
23. Fliers E, Guldenaar SE, Wiersinga WM, Swaab DF. Decreased hypothalamic thyrotropin-releasing hormone gene expression in patients with nonthyroidal illness. J Clin Endocrinol Metab 1997; 82: 4032-4036.
24. Van den Berghe G, de Zegher F, Lauwers; P. Dopamine and the sick euthyroid syndrome in critical illness. Clin Endocrinol 1994; 41: 731-737.
25. Dillmann WH. Cellular action of thyroid hormone on the heart. Thyroid 2002; 12: 447-452.
26. Pachucki J, Burmeister LA, Larsen PR. Thyroid hormone regulates hyperpolarization-activated cyclic nucleotide-gated channel (HCN2) mRNA in the rat heart. Circ Res 1999; 85: 498-503.