Is the low tri-iodothyronine state a crucial factor in determining the outcome of coronary artery bypass patients? Evidence from a clinical pilot study

Journal of Endocrinology

Volumn 175, Issue 3, 2002, Pages 577-586

  Sabatino, I ^b   Cerillo, A G ^a   Ripoli, A ^b   Pilo, A ^b   Glauber, M ^a   Iervasi, G ^b  

^a G PASQUINUCCI HOSPITAL   (Italy)

^b INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LIOTHYRONINE; THYROID HORMONE; THYROXINE;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CARDIOVASCULAR SYSTEM; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CORRELATION ANALYSIS; EVIDENCE BASED MEDICINE; HORMONE METABOLISM; HORMONE SUBSTITUTION; HUMAN; LIOTHYRONINE BLOOD LEVEL; PILOT STUDY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; THYROXINE BLOOD LEVEL; TREATMENT OUTCOME;

AGED; ANALYSIS OF VARIANCE; AREA UNDER CURVE; BLOOD PROTEINS; CORONARY ARTERY BYPASS; CORONARY DISEASE; HUMANS; MIDDLE AGED; POSTOPERATIVE PERIOD; THYROTROPIN; THYROXINE; TREATMENT OUTCOME; TRIIODOTHYRONINE; TRIIODOTHYRONINE, REVERSE;

EID: 0036941049     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1750577     Document Type: Article

References (29)

1. Bacci V, Schussler GC & Kaplan TB 1982 The relationship between serum triiodothyronine and thyrotropin during systemic illness. Journal of Clinical Endocrinology and Metabolism 54 1229-1235.
2. Barriuso Vargas C, Castella Pericas M, Greco E, Sureda Barbosa C, Pomar Moya-Prats JL & Mulet Melia J 1999 Coronary surgery with minimum access and cardiopulmonary bypass. Revista Espanola de Cardiologia 52 445-448.
3. Baum D, Dillar DH & Porte D 1968 Inhibition of insulin release in infants undergoing deep hypothermic cardiovascular surgery. New England Journal of Medicine 279 1309-1314.
4. Bettendorf M, Schmidt KG, Grulich-Henn J, Ulmer HE & Heinrich UE 2000 Tri-iodothyronine treatment in children after cardiac surgery: a double-blind, randomised, placebo-controlled study. Lancet 356 529-534.
5. Borner U, Klimek M, Schoengen H, Lynch J, Peschau C & Schicha H 1995 The influence of various anesthetics on the release and metabolism of thyroid hormones: results of two clinical studies. Anesthesia and Analgesia 81 612-618.
6. Broderick TJ & Wechsler AS 1997 Triiodothyronine in cardiac surgery. Thyroid 7 133-137.
7. Contini M, Iaco A, Iovino T, Teodori G, Di Giammarco G, Mazzei V, Commodo M & Calafiore AM 1999 Current results in off pump surgery. European Journal of Cardiothoracic Surgery 16 S69-S72.
8. Dunn J, Kirsch M, Harness J, Carroll M, Straker J & Sloan H 1974 Hemodynamic, metabolic, and hematologic effects of pulsatile cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery 68 138-147.
9. Dyke CM, Yeh T, Lehman JD, Abd-Elfattah A, Ding M, Wechsler AS & Salter DR 1991 Triiodothyronine-enhanced left ventricular function after ischemic injury. Annals of Thoracic Surgery 52 14-19.
10. Gay R, Gustafson TA, Goldman S & Morkin E 1987 Effects of L-thyroxine in rats with chronic heart failure after myocardium. infarction. American Journal of Physiology 253 H341-H346.
11. Gay R, Graham S, Aguirre M, Goldman S & Morkin E 1988 Effects of 10-12 day treatment with L-thyroxine in rats with myocardial infarction. American Journal of Physiology 255 H801-H806.
12. Gøtzsche SBH & Weeke J 1991 Changes in plasma free thyroid hormones during cardiopulmonary bypass do not indicate triiodothyronine substitution. Journal of Thoracic and Cardiovascular Surgery 104 273-277.
13. Hamilton MA, Stevenson LW, Fonarow GC, Steimle A, Goldhaber JI, Child JS, Chopra IJ, Moriguchi JD & Hage A 1998 Safety and hemodynamic effects of intravenous triiodothyronine in advanced congestive heart failure. American Journal of Cardiology 81 443-447.
14. Holland II FW, Brown PS Jr, Weintraub BD & Clark RE 1991 Cardiopulmonary bypass and thyroid function: a 'euthyroid sick syndrome'. Annals of Thoracic Surgery 52 46-50.
15. Iervasi G, Clerico A, Berri S, Biagini A, Bianchi R & Donato L 1996 Normalization of peripheral thyroid hormone metabolism induced by successful chronic amiodarone treatment in patients with ventricular arrhythmias. European Journal of Clinical Investigation 26 382-390.
16. John DK, Klein I, Gomez M, Helm RE, Ojamaa K, Thomas SJ, Isom WI & Krieger K 1995 Thyroid hormone treatment after coronary-artery bypass surgery. New England Journal of Medicine 333 1522-1527.
17. Klein I & Ojamaa K 2000 Editorial: Thyroid hormone - targeting the heart. Endocrinology 142 11-12.
18. Klemperer JD, Klein I, Gomez M, Helm RE, Ojamaa K, Thomas SJ, Isom OW & Krieger K 1995 Thyroid hormone treatment after coronary-artery bypass surgery. New England Journal of Medicine 333 1522-1527.
19. Mainwaring RD, Lamberti JJ, Billman GF & Nelson JC 1994 Suppression of the pituitary thyroid axis after cardiopulmonary bypass in the neonate. Annals of Thoracic Surgery 58 1078-1082.
20. Mullis-Jansson SL, Argenziano M, Corwin S, Homma S, Weinberg AD, Williams M, Rose EA & Smith CR 1999 A randomized double-blind study of the effect of triiodothyronine on cardiac function and morbidity after coronary bypass surgery. Journal of Thoracic and Cardiovascular Surgery 117 1128-1135.
21. Murzi B, Iervasi G, Masini S, Moschetti R, Vanini V, Zucchelli G & Biagini A 1995 Thyroid hormones homeostasis in pediatric patients during and after cardiopulmonary bypass. Annals of Thoracic Surgery 59 481-485.
22. Novitzky D, Human PA & Cooper DK 1988 Inotropic effect of triiodothyronine following myocardial ischemia and cardiopulmonary bypass: an experimental study in pigs. Annals of Thoracic Surgery 45 50-55.
23. Novitzky D, Fontanet H, Snyder M, Coblio N, Smith D & Parsonnet V 1996 Impact of triiodothyronine on the survival of high-risk patients undergoing open heart surgery. Cardiology 87 509-515.
24. Pappas G, Winter S, Kopriva C & Steele P 1975 Improvement of myocardial and other vital organ functions and metabolism with a simple method of pulsatile flow (IABP) during clinical cardiopulmonary bypass. Surgery 77 34-44.
25. Robuschi G, Medici D, Fesani F, Barboso G, Montermini M, D'Amato L, Gardini E, Borciani E, Dell'Aglio E & Salvi M 1986 Cardiopulmonary bypass: a low T4 and T3 syndrome with blunted thyrotropin response to thyrotropin-releasing hormone. Hormone Research 23 151-158.
26. Salter DR, Cornelius MD & Wechsler AS 1992 Triiodothyronine (T3) and cardiovascular therapeutics: a review. Journal of Cardiac Surgery 7 363-374.
27. Teiger E, Menaschè P, Mansier P, Chevalier B, Lajeunie E, Bloch G & Piwnica A 1993 Triiodothyronine therapy in open-heart surgery: from hope to disappointment. European Heart Journal 14 629-633.
28. Wartofsky L & Burman KD 1982 Alterations in thyroid function in patients with systemic illness: the 'euthyroid sick syndrome'. Endocrine Reviews 3 164-217.
29. Welsby IJ, Bennet-Guerrero E, Atwell D, White WD, Newman MF, Smith PK & Mythen MG 2002 The association of complication type with mortality and prolonged stay after cardiac surgery with cardiopulmonary bypass. Anesthesia and Analgesia 94 1072-1078.