메뉴 건너뛰기




Volumn 71, Issue 3, 2006, Pages 574-585

Oxidized low-density lipoprotein depletes PKCα and attenuates reactive oxygen species formation in monocytes/macrophages

Author keywords

Inflammation; Lipoproteins; Monocytes macrophages; Oxygen radicals; Protein kinase C

Indexed keywords

GO 6967; LOW DENSITY LIPOPROTEIN; PROTEIN KINASE C ALPHA; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

EID: 33746308410     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2006.05.023     Document Type: Article
Times cited : (12)

References (45)
  • 1
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson G.K. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 352 (2005) 1685-1695
    • (2005) N Engl J Med , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 2
    • 0022523129 scopus 로고
    • Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque
    • Jonasson L., Holm J., Skalli O., Bondjers G., and Hansson G.K. Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque. Arteriosclerosis 6 (1986) 131-138
    • (1986) Arteriosclerosis , vol.6 , pp. 131-138
    • Jonasson, L.1    Holm, J.2    Skalli, O.3    Bondjers, G.4    Hansson, G.K.5
  • 3
    • 0038721160 scopus 로고    scopus 로고
    • Oxidized low-density lipoproteins: what is understood and what remains to be clarified
    • Itabe H. Oxidized low-density lipoproteins: what is understood and what remains to be clarified. Biol Pharm Bull 26 (2003) 1-9
    • (2003) Biol Pharm Bull , vol.26 , pp. 1-9
    • Itabe, H.1
  • 5
    • 0033048632 scopus 로고    scopus 로고
    • Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines
    • Frostegard J., Ulfgren A.K., Nyberg P., Hedin U., Swedenborg J., Andersson U., et al. Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis 145 (1999) 33-43
    • (1999) Atherosclerosis , vol.145 , pp. 33-43
    • Frostegard, J.1    Ulfgren, A.K.2    Nyberg, P.3    Hedin, U.4    Swedenborg, J.5    Andersson, U.6
  • 6
    • 24944452395 scopus 로고    scopus 로고
    • Thematic review series: the immune system and atherogenesis. Cytokines affecting endothelial and smooth muscle cells in vascular disease
    • Raines E.W., and Ferri N. Thematic review series: the immune system and atherogenesis. Cytokines affecting endothelial and smooth muscle cells in vascular disease. J Lipid Res 46 (2005) 1081-1092
    • (2005) J Lipid Res , vol.46 , pp. 1081-1092
    • Raines, E.W.1    Ferri, N.2
  • 7
    • 0029079926 scopus 로고
    • Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E
    • Smith J.D., Trogan E., Ginsberg M., Grigaux C., Tian J., and Miyata M. Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E. Proc Natl Acad Sci U S A 92 (1995) 8264-8268
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8264-8268
    • Smith, J.D.1    Trogan, E.2    Ginsberg, M.3    Grigaux, C.4    Tian, J.5    Miyata, M.6
  • 8
    • 0035901582 scopus 로고    scopus 로고
    • Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes
    • Ehara S., Ueda M., Naruko T., Haze K., Itoh A., Otsuka M., et al. Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation 103 (2001) 1955-1960
    • (2001) Circulation , vol.103 , pp. 1955-1960
    • Ehara, S.1    Ueda, M.2    Naruko, T.3    Haze, K.4    Itoh, A.5    Otsuka, M.6
  • 9
    • 0033527446 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein induces macrophage respiratory burst via its protein moiety: a novel pathway in atherogenesis?
    • Nguyen-Khoa T., Massy Z.A., Witko-Sarsat V., Canteloup S., Kebede M., Lacour B., et al. Oxidized low-density lipoprotein induces macrophage respiratory burst via its protein moiety: a novel pathway in atherogenesis?. Biochem Biophys Res Commun 263 (1999) 804-809
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 804-809
    • Nguyen-Khoa, T.1    Massy, Z.A.2    Witko-Sarsat, V.3    Canteloup, S.4    Kebede, M.5    Lacour, B.6
  • 10
    • 0036395928 scopus 로고    scopus 로고
    • Macrophage signaling and respiratory burst
    • Iles K.E., and Forman H.J. Macrophage signaling and respiratory burst. Immunol Res 26 (2002) 95-105
    • (2002) Immunol Res , vol.26 , pp. 95-105
    • Iles, K.E.1    Forman, H.J.2
  • 11
    • 0037108109 scopus 로고    scopus 로고
    • Current molecular models for NADPH oxidase regulation by Rac GTPase
    • Bokoch G.M., and Diebold B.A. Current molecular models for NADPH oxidase regulation by Rac GTPase. Blood 100 (2002) 2692-2696
    • (2002) Blood , vol.100 , pp. 2692-2696
    • Bokoch, G.M.1    Diebold, B.A.2
  • 12
    • 0037129803 scopus 로고    scopus 로고
    • Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation
    • Fontayne A., Dang P.M., Gougerot-Pocidalo M.A., and El-Benna J. Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation. Biochemistry 41 (2002) 7743-7750
    • (2002) Biochemistry , vol.41 , pp. 7743-7750
    • Fontayne, A.1    Dang, P.M.2    Gougerot-Pocidalo, M.A.3    El-Benna, J.4
  • 13
    • 0037337159 scopus 로고    scopus 로고
    • Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm
    • Newton A.C. Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. Biochem J 370 (2003) 361-371
    • (2003) Biochem J , vol.370 , pp. 361-371
    • Newton, A.C.1
  • 14
    • 0032585532 scopus 로고    scopus 로고
    • Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)
    • Dutil E.M., Toker A., and Newton A.C. Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1). Curr Biol 8 (1998) 1366-1375
    • (1998) Curr Biol , vol.8 , pp. 1366-1375
    • Dutil, E.M.1    Toker, A.2    Newton, A.C.3
  • 15
    • 0029757465 scopus 로고    scopus 로고
    • Dephosphorylation of activated protein kinase C contributes to downregulation by bryostatin
    • Lee H.W., Smith L., Pettit G.R., and Bingham Smith J. Dephosphorylation of activated protein kinase C contributes to downregulation by bryostatin. Am J Physiol 271 (1996) C304-C311
    • (1996) Am J Physiol , vol.271
    • Lee, H.W.1    Smith, L.2    Pettit, G.R.3    Bingham Smith, J.4
  • 16
    • 0029812896 scopus 로고    scopus 로고
    • Ubiquitination of protein kinase C-alpha and degradation by the proteasome
    • Lee H.W., Smith L., Pettit G.R., Vinitsky A., and Smith J.B. Ubiquitination of protein kinase C-alpha and degradation by the proteasome. J Biol Chem 271 (1996) 20973-20976
    • (1996) J Biol Chem , vol.271 , pp. 20973-20976
    • Lee, H.W.1    Smith, L.2    Pettit, G.R.3    Vinitsky, A.4    Smith, J.B.5
  • 17
    • 1242339601 scopus 로고    scopus 로고
    • Identification of two distinct pathways of protein kinase Calpha down-regulation in intestinal epithelial cells
    • Leontieva O.V., and Black J.D. Identification of two distinct pathways of protein kinase Calpha down-regulation in intestinal epithelial cells. J Biol Chem 279 (2004) 5788-5801
    • (2004) J Biol Chem , vol.279 , pp. 5788-5801
    • Leontieva, O.V.1    Black, J.D.2
  • 18
    • 17044431078 scopus 로고    scopus 로고
    • Activation-induced depletion of protein kinase C alpha provokes desensitization of monocytes/macrophages in sepsis
    • von Knethen A., Tautenhahn A., Link H., Lindemann D., and Brune B. Activation-induced depletion of protein kinase C alpha provokes desensitization of monocytes/macrophages in sepsis. J Immunol 174 (2005) 4960-4965
    • (2005) J Immunol , vol.174 , pp. 4960-4965
    • von Knethen, A.1    Tautenhahn, A.2    Link, H.3    Lindemann, D.4    Brune, B.5
  • 19
    • 0037087449 scopus 로고    scopus 로고
    • Dualism of oxidized lipoproteins in provoking and attenuating the oxidative burst in macrophages: role of peroxisome proliferator-activated receptor-gamma
    • Fischer B., von Knethen A., and Brune B. Dualism of oxidized lipoproteins in provoking and attenuating the oxidative burst in macrophages: role of peroxisome proliferator-activated receptor-gamma. J Immunol 168 (2002) 2828-2834
    • (2002) J Immunol , vol.168 , pp. 2828-2834
    • Fischer, B.1    von Knethen, A.2    Brune, B.3
  • 20
    • 0026024295 scopus 로고
    • A simple test for predisposition to LDL oxidation based on the fluorescence development during copper-catalyzed oxidative modification
    • Cominacini L., Garbin U., Davoli A., Micciolo R., Bosello O., Gaviraghi G., et al. A simple test for predisposition to LDL oxidation based on the fluorescence development during copper-catalyzed oxidative modification. J Lipid Res 32 (1991) 349-358
    • (1991) J Lipid Res , vol.32 , pp. 349-358
    • Cominacini, L.1    Garbin, U.2    Davoli, A.3    Micciolo, R.4    Bosello, O.5    Gaviraghi, G.6
  • 21
    • 0030069738 scopus 로고    scopus 로고
    • Mechanisms involved in the in vitro modification of low density lipoprotein by human umbilical vein endothelial cells and copper ions
    • Cominacini L., Garbin U., De Santis A., Campagnola M., Davoli A., Pasini A.F., et al. Mechanisms involved in the in vitro modification of low density lipoprotein by human umbilical vein endothelial cells and copper ions. J Lipid Mediat Cell Signal 13 (1996) 19-33
    • (1996) J Lipid Mediat Cell Signal , vol.13 , pp. 19-33
    • Cominacini, L.1    Garbin, U.2    De Santis, A.3    Campagnola, M.4    Davoli, A.5    Pasini, A.F.6
  • 22
    • 0032247243 scopus 로고    scopus 로고
    • Oxidized LDL and Lp(a). Preparation, modification, and analysis
    • Galle J., and Wanner C. Oxidized LDL and Lp(a). Preparation, modification, and analysis. Methods Mol Biol 108 (1998) 119-130
    • (1998) Methods Mol Biol , vol.108 , pp. 119-130
    • Galle, J.1    Wanner, C.2
  • 23
    • 0035958877 scopus 로고    scopus 로고
    • Activation of NF-kappa B via the Ikappa B kinase complex is both essential and sufficient for proinflammatory gene expression in primary endothelial cells
    • Denk A., Goebeler M., Schmid S., Berberich I., Ritz O., Lindemann D., et al. Activation of NF-kappa B via the Ikappa B kinase complex is both essential and sufficient for proinflammatory gene expression in primary endothelial cells. J Biol Chem 276 (2001) 28451-28458
    • (2001) J Biol Chem , vol.276 , pp. 28451-28458
    • Denk, A.1    Goebeler, M.2    Schmid, S.3    Berberich, I.4    Ritz, O.5    Lindemann, D.6
  • 24
    • 0030912893 scopus 로고    scopus 로고
    • Efficient pseudotyping of murine leukemia virus particles with chimeric human foamy virus envelope proteins
    • Lindemann D., Bock M., Schweizer M., and Rethwilm A. Efficient pseudotyping of murine leukemia virus particles with chimeric human foamy virus envelope proteins. J Virol 71 (1997) 4815-4820
    • (1997) J Virol , vol.71 , pp. 4815-4820
    • Lindemann, D.1    Bock, M.2    Schweizer, M.3    Rethwilm, A.4
  • 27
    • 17644394600 scopus 로고    scopus 로고
    • Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence
    • Zhao H., Joseph J., Fales H.M., Sokoloski E.A., Levine R.L., Vasquez-Vivar J., et al. Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence. Proc Natl Acad Sci U S A 102 (2005) 5727-5732
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 5727-5732
    • Zhao, H.1    Joseph, J.2    Fales, H.M.3    Sokoloski, E.A.4    Levine, R.L.5    Vasquez-Vivar, J.6
  • 28
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Droge W. Free radicals in the physiological control of cell function. Physiol Rev 82 (2002) 47-95
    • (2002) Physiol Rev , vol.82 , pp. 47-95
    • Droge, W.1
  • 29
    • 0035181940 scopus 로고    scopus 로고
    • Mechanisms for oxidizing low-density lipoprotein. Insights from patterns of oxidation products in the artery wall and from mouse models of atherosclerosis
    • Gaut J.P., and Heinecke J.W. Mechanisms for oxidizing low-density lipoprotein. Insights from patterns of oxidation products in the artery wall and from mouse models of atherosclerosis. Trends Cardiovasc Med 11 (2001) 103-112
    • (2001) Trends Cardiovasc Med , vol.11 , pp. 103-112
    • Gaut, J.P.1    Heinecke, J.W.2
  • 30
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy L., Tontonoz P., Alvarez J.G., Chen H., and Evans R.M. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 93 (1998) 229-240
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 31
    • 0035127757 scopus 로고    scopus 로고
    • Delayed activation of PPARgamma by LPS and IFN-gamma attenuates the oxidative burst in macrophages
    • Von Knethen A.A., and Brune B. Delayed activation of PPARgamma by LPS and IFN-gamma attenuates the oxidative burst in macrophages. FASEB J 15 (2001) 535-544
    • (2001) FASEB J , vol.15 , pp. 535-544
    • Von Knethen, A.A.1    Brune, B.2
  • 32
    • 0031724132 scopus 로고    scopus 로고
    • Potent inhibitory effect of troglitazone on carotid arterial wall thickness in type 2 diabetes
    • Minamikawa J., Tanaka S., Yamauchi M., Inoue D., and Koshiyama H. Potent inhibitory effect of troglitazone on carotid arterial wall thickness in type 2 diabetes. J Clin Endocrinol Metab 83 (1998) 1818-1820
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1818-1820
    • Minamikawa, J.1    Tanaka, S.2    Yamauchi, M.3    Inoue, D.4    Koshiyama, H.5
  • 33
    • 0034878539 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and their role in the vessel wall: possible mediators of cardiovascular risk?
    • Marx N., Libby P., and Plutzky J. Peroxisome proliferator-activated receptors (PPARs) and their role in the vessel wall: possible mediators of cardiovascular risk?. J Cardiovasc Risk 8 (2001) 203-210
    • (2001) J Cardiovasc Risk , vol.8 , pp. 203-210
    • Marx, N.1    Libby, P.2    Plutzky, J.3
  • 34
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPARgamma
    • Lehrke M., and Lazar M.A. The many faces of PPARgamma. Cell 123 (2005) 993-999
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 35
    • 2942670612 scopus 로고    scopus 로고
    • PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: role of diacylglycerol kinase
    • Verrier E., Wang L., Wadham C., Albanese N., Hahn C., Gamble J.R., et al. PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: role of diacylglycerol kinase. Circ Res 94 (2004) 1515-1522
    • (2004) Circ Res , vol.94 , pp. 1515-1522
    • Verrier, E.1    Wang, L.2    Wadham, C.3    Albanese, N.4    Hahn, C.5    Gamble, J.R.6
  • 36
    • 0034283687 scopus 로고    scopus 로고
    • Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW 264.7 cells
    • Larsen E.C., DiGennaro J.A., Saito N., Mehta S., Loegering D.J., Mazurkiewicz J.E., et al. Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW 264.7 cells. J Immunol 165 (2000) 2809-2817
    • (2000) J Immunol , vol.165 , pp. 2809-2817
    • Larsen, E.C.1    DiGennaro, J.A.2    Saito, N.3    Mehta, S.4    Loegering, D.J.5    Mazurkiewicz, J.E.6
  • 37
    • 0023052241 scopus 로고
    • Studies and perspectives of protein kinase C
    • Nishizuka Y. Studies and perspectives of protein kinase C. Science 233 (1986) 305-312
    • (1986) Science , vol.233 , pp. 305-312
    • Nishizuka, Y.1
  • 38
    • 13944257428 scopus 로고    scopus 로고
    • Role of phorbol ester localization in determining protein kinase C or RasGRP3 translocation: real-time analysis using fluorescent ligands and proteins
    • Braun D.C., Cao Y., Wang S., Garfield S.H., Hur G.M., and Blumberg P.M. Role of phorbol ester localization in determining protein kinase C or RasGRP3 translocation: real-time analysis using fluorescent ligands and proteins. Mol Cancer Ther 4 (2005) 141-150
    • (2005) Mol Cancer Ther , vol.4 , pp. 141-150
    • Braun, D.C.1    Cao, Y.2    Wang, S.3    Garfield, S.H.4    Hur, G.M.5    Blumberg, P.M.6
  • 39
    • 0346100518 scopus 로고    scopus 로고
    • Scavenger receptors for oxidized and glycated proteins
    • Horiuchi S., Sakamoto Y., and Sakai M. Scavenger receptors for oxidized and glycated proteins. Amino Acids 25 (2003) 283-292
    • (2003) Amino Acids , vol.25 , pp. 283-292
    • Horiuchi, S.1    Sakamoto, Y.2    Sakai, M.3
  • 40
    • 0035958019 scopus 로고    scopus 로고
    • The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide
    • Cominacini L., Rigoni A., Pasini A.F., Garbin U., Davoli A., Campagnola M., et al. The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide. J Biol Chem 276 (2001) 13750-13755
    • (2001) J Biol Chem , vol.276 , pp. 13750-13755
    • Cominacini, L.1    Rigoni, A.2    Pasini, A.F.3    Garbin, U.4    Davoli, A.5    Campagnola, M.6
  • 41
    • 0035093166 scopus 로고    scopus 로고
    • Oxidized-LDL enhances coronary vasoconstriction by increasing the activity of protein kinase C isoforms alpha and epsilon
    • Giardina J.B., Tanner D.J., and Khalil R.A. Oxidized-LDL enhances coronary vasoconstriction by increasing the activity of protein kinase C isoforms alpha and epsilon. Hypertension 37 (2001) 561-568
    • (2001) Hypertension , vol.37 , pp. 561-568
    • Giardina, J.B.1    Tanner, D.J.2    Khalil, R.A.3
  • 42
    • 0038301121 scopus 로고    scopus 로고
    • LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells
    • Li D., Liu L., Chen H., Sawamura T., and Mehta J.L. LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells. Arterioscler Thromb Vasc Biol 23 (2003) 816-821
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 816-821
    • Li, D.1    Liu, L.2    Chen, H.3    Sawamura, T.4    Mehta, J.L.5
  • 43
    • 13844255039 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein increases superoxide production by endothelial nitric oxide synthase by inhibiting PKCalpha
    • Fleming I., Mohamed A., Galle J., Turchanowa L., Brandes R.P., Fisslthaler B., et al. Oxidized low-density lipoprotein increases superoxide production by endothelial nitric oxide synthase by inhibiting PKCalpha. Cardiovasc Res 65 (2005) 897-906
    • (2005) Cardiovasc Res , vol.65 , pp. 897-906
    • Fleming, I.1    Mohamed, A.2    Galle, J.3    Turchanowa, L.4    Brandes, R.P.5    Fisslthaler, B.6
  • 44
    • 0033781544 scopus 로고    scopus 로고
    • Protein kinase C activation and its pharmacological inhibition in vascular disease
    • Meier M., and King G.L. Protein kinase C activation and its pharmacological inhibition in vascular disease. Vasc Med 5 (2000) 173-185
    • (2000) Vasc Med , vol.5 , pp. 173-185
    • Meier, M.1    King, G.L.2
  • 45
    • 0034852862 scopus 로고    scopus 로고
    • Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes
    • Idris I., Gray S., and Donnelly R. Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes. Diabetologia 44 (2001) 659-673
    • (2001) Diabetologia , vol.44 , pp. 659-673
    • Idris, I.1    Gray, S.2    Donnelly, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.