메뉴 건너뛰기




Volumn 22, Issue 4, 2006, Pages 412-416

Advantages and disadvantages of lumping together gastroesophageal reflux disease and dyspepsia

Author keywords

Acid secretion; Gastric emptying; Helicobacter pylori; Hypersensitivity

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; BACLOFEN; HISTAMINE H2 RECEPTOR ANTAGONIST; OMEPRAZOLE; PROKINETIC AGENT; PROTON PUMP INHIBITOR; RANITIDINE;

EID: 33746260248     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mog.0000231817.26020.7e     Document Type: Review
Times cited : (2)

References (40)
  • 1
    • 17144395168 scopus 로고    scopus 로고
    • Prevalence of functional gastrointestinal disorders in a population of subjects consulting for gastroesophageal reflux disease in general practice
    • Guillemot F, Ducrotte P, Bueono L. Prevalence of functional gastrointestinal disorders in a population of subjects consulting for gastroesophageal reflux disease in general practice. Gastroenterol Clin Biol 2005; 29:243-246. This important paper describes frequent overlap of GERD and functional dyspepsia.
    • (2005) Gastroenterol Clin Biol , vol.29 , pp. 243-246
    • Guillemot, F.1    Ducrotte, P.2    Bueono, L.3
  • 2
    • 25444467745 scopus 로고    scopus 로고
    • Prevalence of acid reflux in functional dyspepsia and its association with symptom profile
    • Tack J, Caenepeel P, Arts J, et al. Prevalence of acid reflux in functional dyspepsia and its association with symptom profile. Gut 2005; 54:1370-1376. The authors describe thought-provoking observations on the overlap between GERD and dyspepsia. Most strikingly, epigastric pain was found to be associated with pathological oesophageal acid exposure.
    • (2005) Gut , vol.54 , pp. 1370-1376
    • Tack, J.1    Caenepeel, P.2    Arts, J.3
  • 3
    • 19244380563 scopus 로고    scopus 로고
    • Gastro-oesophageal reflux disease in primary care: An international study of different treatment strategies with omeprazole
    • Carlsson R, Dent J, Watts R, et al. Gastro-oesophageal reflux disease in primary care: an international study of different treatment strategies with omeprazole. Eur J Gastroenterol Hepatol 1998; 10:119-124.
    • (1998) Eur J Gastroenterol Hepatol , vol.10 , pp. 119-124
    • Carlsson, R.1    Dent, J.2    Watts, R.3
  • 4
    • 0032977314 scopus 로고    scopus 로고
    • Quality of life in patients with heartburn but without esophagitis: Effects of treatment with omeprazole
    • Havelund T, Lind T, Wiklund I, et al. Quality of life in patients with heartburn but without esophagitis: effects of treatment with omeprazole. Am J Gastroenterol 1999; 94:1782-1789.
    • (1999) Am J Gastroenterol , vol.94 , pp. 1782-1789
    • Havelund, T.1    Lind, T.2    Wiklund, I.3
  • 5
    • 0026786996 scopus 로고
    • Epidemiology and natural history of gastro-oesophageal reflux disease
    • Spechler SJ. Epidemiology and natural history of gastro-oesophageal reflux disease. Digestion 1992; 51 (Suppl 1):24-29.
    • (1992) Digestion , vol.51 , Issue.1 SUPPL. , pp. 24-29
    • Spechler, S.J.1
  • 6
    • 0024592494 scopus 로고
    • Epidemiology of reflux disease and reflux esophagitis
    • Wienbeck M, Barnert J. Epidemiology of reflux disease and reflux esophagitis. Scand J Gastroenterol 1989; 156 (Suppl):7-13.
    • (1989) Scand J Gastroenterol , vol.156 , Issue.SUPPL. , pp. 7-13
    • Wienbeck, M.1    Barnert, J.2
  • 7
    • 0030442522 scopus 로고    scopus 로고
    • Relevance of norm values as part of the documentation of quality of life instruments for use in upper gastrointestinal disease
    • Dimenas E, Carlsson G, Glise H, et al. Relevance of norm values as part of the documentation of quality of life instruments for use in upper gastrointestinal disease. Scand J Gastroenterol 1996; 221 (Suppl):8-13.
    • (1996) Scand J Gastroenterol , vol.221 , Issue.SUPPL. , pp. 8-13
    • Dimenas, E.1    Carlsson, G.2    Glise, H.3
  • 8
    • 0026627764 scopus 로고
    • Three year follow up of patients with gastro-oesophageal reflux disease
    • Schindlbeck NE, Klauser AG, Berghammer G, et al. Three year follow up of patients with gastro-oesophageal reflux disease. Gut 1992; 33:1016-1019.
    • (1992) Gut , vol.33 , pp. 1016-1019
    • Schindlbeck, N.E.1    Klauser, A.G.2    Berghammer, G.3
  • 9
    • 0031022019 scopus 로고    scopus 로고
    • Natural course of gastroesophageal reflux disease: 17-22 Year follow-up of 60 patients
    • Isolauri J, Luostarinen M, Isolauri E, et al. Natural course of gastroesophageal reflux disease: 17-22 year follow-up of 60 patients. Am J Gastroenterol 1997; 92:37-41.
    • (1997) Am J Gastroenterol , vol.92 , pp. 37-41
    • Isolauri, J.1    Luostarinen, M.2    Isolauri, E.3
  • 10
    • 23844476465 scopus 로고    scopus 로고
    • Review: What doe we mean by GERD? Definition and diagnosis
    • Jones R, Galmiche JP. Review: What doe we mean by GERD? Definition and diagnosis. Aliment Pharmacol Ther 2005; 22 (Suppl 1):2-10. This is a nice, up-to-date review of the techniques that can be used to diagnose GERD. Only the authors' evaluation of 24-h pH/impedance monitoring falls somewhat short.
    • (2005) Aliment Pharmacol Ther , vol.22 , Issue.1 SUPPL. , pp. 2-10
    • Jones, R.1    Galmiche, J.P.2
  • 11
    • 0032998835 scopus 로고    scopus 로고
    • This is an evidence-based appraisal of reflux disease management: The Genval Workshop Report
    • Dent J, Brun J, Fendrick MA, et al. This is an evidence-based appraisal of reflux disease management: the Genval Workshop Report. Gut 1999; 44 (Suppl 2):1-16.
    • (1999) Gut , vol.44 , Issue.2 SUPPL. , pp. 1-16
    • Dent, J.1    Brun, J.2    Fendrick, M.A.3
  • 12
    • 0029980832 scopus 로고    scopus 로고
    • Clinical esophageal pH recording: A technical review for practice guideline development
    • Kahrilas PJ, Quigley EM. Clinical esophageal pH recording: a technical review for practice guideline development. Gastroenterology 1996; 110:1982-1996.
    • (1996) Gastroenterology , vol.110 , pp. 1982-1996
    • Kahrilas, P.J.1    Quigley, E.M.2
  • 13
    • 0029052198 scopus 로고
    • Lowered oesophageal sensory thresholds in patients with symptomatic but not excess gastro-oesophageal reflux: Evidence for a spectrum of visceral sensitivity in GORD
    • Trimble KC, Pryde A, Heading RC. Lowered oesophageal sensory thresholds in patients with symptomatic but not excess gastro-oesophageal reflux: evidence for a spectrum of visceral sensitivity in GORD. Gut 1995; 37:7-12.
    • (1995) Gut , vol.37 , pp. 7-12
    • Trimble, K.C.1    Pryde, A.2    Heading, R.C.3
  • 14
    • 0030883417 scopus 로고    scopus 로고
    • Treating the symptoms of gastro-oesophageal reflux disease: A double-blind comparison of omeprazole and cisapride
    • Galmiche J-P, Barthelemy P, Hamelin B. Treating the symptoms of gastro-oesophageal reflux disease: a double-blind comparison of omeprazole and cisapride. Aliment Pharmacol Ther 1997; 11:765-773.
    • (1997) Aliment Pharmacol Ther , vol.11 , pp. 765-773
    • Galmiche, J.-P.1    Barthelemy, P.2    Hamelin, B.3
  • 15
    • 28144454058 scopus 로고    scopus 로고
    • Symptom association analysis in ambulatory gastro-oesophageal reflux monitoring
    • Bredenoord AJ, Weusten BLAM, Smout AJPM. Symptom association analysis in ambulatory gastro-oesophageal reflux monitoring. Gut 2005; 54:1810-1817. This is an overview of particular interest for all those actively involved in performing 24-h esophageal pH and impedance monitoring.
    • (2005) Gut , vol.54 , pp. 1810-1817
    • Bredenoord, A.J.1    Weusten, B.L.A.M.2    Smout, A.J.P.M.3
  • 16
    • 0036735045 scopus 로고    scopus 로고
    • The effect of baclofen on gastro-oesophageal reflux, lower oesophageal sphincter function and reflux symptoms in patients with reflux disease
    • van Herwaarden MA, Samsom M, Rydholm H, Smout AJPM. The effect of baclofen on gastro-oesophageal reflux, lower oesophageal sphincter function and reflux symptoms in patients with reflux disease. Aliment Pharmacol Ther 2002; 16:1655-1662.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 1655-1662
    • Van Herwaarden, M.A.1    Samsom, M.2    Rydholm, H.3    Smout, A.J.P.M.4
  • 17
    • 0036136088 scopus 로고    scopus 로고
    • Control of transient lower oesophageal sphincter relaxations and reflux by the GABAb agonist baclofen in patients with gastro-oesophageal reflux disease
    • Zhang Q, Lehmann A, Rigda R, et al. Control of transient lower oesophageal sphincter relaxations and reflux by the GABAb agonist baclofen in patients with gastro-oesophageal reflux disease. Gut 2002; 50:19-24.
    • (2002) Gut , vol.50 , pp. 19-24
    • Zhang, Q.1    Lehmann, A.2    Rigda, R.3
  • 18
    • 26844571501 scopus 로고    scopus 로고
    • Laparoscopic antireflux surgery: Five-year results and beyond in 1340 patients
    • Pessaux P, Arnaud JP, Delattre JF, et al. Laparoscopic antireflux surgery: five-year results and beyond in 1340 patients. Arch Surg 2005; 140:946-951. This impressively large fundoplication follow-up study confirmed that antireflux surgery, in experienced hands, is effective in about 90% of cases.
    • (2005) Arch Surg , vol.140 , pp. 946-951
    • Pessaux, P.1    Arnaud, J.P.2    Delattre, J.F.3
  • 19
    • 28944445698 scopus 로고    scopus 로고
    • Review article: Alternative approaches to the long-term management of GERD
    • Fennerty MB. Review article: alternative approaches to the long-term management of GERD. Aliment Pharmacol Ther 2005; (Suppl 3):39-44. Do not expect to find too many really 'alternative' options, but the author has given his sensible view on the currently available treatment modalities.
    • (2005) Aliment Pharmacol Ther , Issue.3 SUPPL. , pp. 39-44
    • Fennerty, M.B.1
  • 20
    • 15744402516 scopus 로고    scopus 로고
    • Nonresorbable copolymer implantation for gastroesophageal reflux disease: A randomized sham-controlled multicenter trial
    • Devière J, Costamagna G, Neuhaus H, et al. Nonresorbable copolymer implantation for gastroesophageal reflux disease: A randomized sham-controlled multicenter trial. Gastroenterology 2005; 128:532-540. The authors of this multicenter European trial are to be complimented for choosing a sham-controlled design, which is, regrettably but incontrovertibly, the only way in which the effect of surgical procedures on subjective endpoints can be assessed.
    • (2005) Gastroenterology , vol.128 , pp. 532-540
    • Devière, J.1    Costamagna, G.2    Neuhaus, H.3
  • 21
    • 0032850647 scopus 로고    scopus 로고
    • Functional gastroduodenal disorders
    • Talley NJ, Stanghellini V, Heading RC, et al. Functional gastroduodenal disorders. Gut 1999; 45 (Suppl):II37-II42.
    • (1999) Gut , vol.45 , Issue.SUPPL.
    • Talley, N.J.1    Stanghellini, V.2    Heading, R.C.3
  • 22
    • 23844523815 scopus 로고    scopus 로고
    • Dyspepsia consulters and patterns of management: A population-based study
    • Ahlawat SK, Richard Locke G, Weaver AL, et al. Dyspepsia consulters and patterns of management: a population-based study. Aliment Pharmacol Ther 2005; 22:251-259. This recent study still dared to identify a subgroup of reflux-like dyspepsia. In the well known Olmsted County population ulcer-like, dysmotility-like and reflux-like dyspepsia are about equally prevalent.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 251-259
    • Ahlawat, S.K.1    Richard Locke, G.2    Weaver, A.L.3
  • 23
    • 0026547741 scopus 로고
    • Dyspepsia and dyspepsia subgroups: A population-based study
    • Talley NJ, Zinsmeister AR, Schleck CD, et al. Dyspepsia and dyspepsia subgroups: a population-based study. Gastroenterology 1992; 102:1259-1268.
    • (1992) Gastroenterology , vol.102 , pp. 1259-1268
    • Talley, N.J.1    Zinsmeister, A.R.2    Schleck, C.D.3
  • 24
    • 0027185528 scopus 로고
    • U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact
    • Drossman DA, Li Z, Andruzzi E, et al. U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact. Dig Dis Sci 1993; 38:1569-1580.
    • (1993) Dig Dis Sci , vol.38 , pp. 1569-1580
    • Drossman, D.A.1    Li, Z.2    Andruzzi, E.3
  • 25
    • 27844482023 scopus 로고    scopus 로고
    • How useful are the Rome II criteria for identification of upper gastrointestinal disorders in general practice?
    • Farup PG, Vandvik PO, Aabakken L. How useful are the Rome II criteria for identification of upper gastrointestinal disorders in general practice? Scand J Gastroenterol 2005; 40:1284-1289. This makes fascinating reading. The authors politely make clear that the Rome II criteria fail to deliver in general practice.
    • (2005) Scand J Gastroenterol , vol.40 , pp. 1284-1289
    • Farup, P.G.1    Vandvik, P.O.2    Aabakken, L.3
  • 26
    • 0031717745 scopus 로고    scopus 로고
    • Disturbed solid-phase gastric emptying in functional dyspepsia. A meta-analysis
    • Quartero AO, De Wit NJ, Lodder AC, et al. Disturbed solid-phase gastric emptying in functional dyspepsia. A meta-analysis. Dig Dis Sci 1998; 43:2028-2033.
    • (1998) Dig Dis Sci , vol.43 , pp. 2028-2033
    • Quartero, A.O.1    De Wit, N.J.2    Lodder, A.C.3
  • 27
    • 0033863334 scopus 로고    scopus 로고
    • Differences in gastric mechanosensory function after repeated ramp distensions in non-consulters with dyspepsia and healthy controls
    • Holtmann G, Gschossmann J, Neufang-Huber J, et al. Differences in gastric mechanosensory function after repeated ramp distensions in non-consulters with dyspepsia and healthy controls. Gut 2000; 47:332-336.
    • (2000) Gut , vol.47 , pp. 332-336
    • Holtmann, G.1    Gschossmann, J.2    Neufang-Huber, J.3
  • 28
    • 0031902761 scopus 로고    scopus 로고
    • Altered vagal and intestinal mechanosensory function in chronic unexplained dyspepsia
    • Holtmann G, Goebell H, Jockenhoevel F, Talley NJ. Altered vagal and intestinal mechanosensory function in chronic unexplained dyspepsia. Gut 1998; 42:501-506.
    • (1998) Gut , vol.42 , pp. 501-506
    • Holtmann, G.1    Goebell, H.2    Jockenhoevel, F.3    Talley, N.J.4
  • 30
    • 0034837093 scopus 로고    scopus 로고
    • Symptoms associated with hypersensitivity to gastric distension in functional dyspepsia
    • Tack J, Caenepeel P, Fischler B, et al. Symptoms associated with hypersensitivity to gastric distension in functional dyspepsia. Gastroenterology 2001; 121:526-535.
    • (2001) Gastroenterology , vol.121 , pp. 526-535
    • Tack, J.1    Caenepeel, P.2    Fischler, B.3
  • 31
    • 0033047694 scopus 로고    scopus 로고
    • Abnormal clearance of exogenous acid and increased acid sensitivity of the proximal duodenum in dyspeptic patients
    • Samsom M, Verhagen MAMT, Van Berge Henegouwen GP, Smout AJPM. Abnormal clearance of exogenous acid and increased acid sensitivity of the proximal duodenum in dyspeptic patients. Gastroenterology 1999; 116:515-520.
    • (1999) Gastroenterology , vol.116 , pp. 515-520
    • Samsom, M.1    Verhagen, M.A.M.T.2    Van Berge Henegouwen, G.P.3    Smout, A.J.P.M.4
  • 32
    • 33644873654 scopus 로고    scopus 로고
    • Initial management strategies for dyspepsia
    • Delaney B, Ford AC, Forman D, et al. Initial management strategies for dyspepsia. Cochrane Database Syst Rev 2005; 19:CD001961. This meta-analysis of 25 rather miscellaneous papers reports comparisons of one or more ways to deal with dyspeptic patients. Inadequate exclusion of GERD patients is identified as a confounding factor.
    • (2005) Cochrane Database Syst Rev , vol.19
    • Delaney, B.1    Ford, A.C.2    Forman, D.3
  • 33
    • 22744457475 scopus 로고    scopus 로고
    • A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in Helicobacter pylori negative, primary care patients with dyspepsia: The CADET-HN study
    • Veldhuyzen van Zanten SJO, Chiba N, Armstrong D, et al. A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in Helicobacter pylori negative, primary care patients with dyspepsia: the CADET-HN study. Am J Gastroenterol 2005; 100:1477-1488. This is another example of a study in which efficacy of PPI treatment is demonstrated while doubt about pollution with GERD patients is not taken away.
    • (2005) Am J Gastroenterol , vol.100 , pp. 1477-1488
    • Veldhuyzen Van Zanten, S.J.O.1    Chiba, N.2    Armstrong, D.3
  • 34
    • 0032564695 scopus 로고    scopus 로고
    • Symptomatic benefit from eradicating Helicobacter pylori infection in patients with nonulcer dyspepsia
    • McColl K, Murray L, El-Omar E, et al. Symptomatic benefit from eradicating Helicobacter pylori infection in patients with nonulcer dyspepsia. N Engl J Med 1998; 339:1869-1874.
    • (1998) N Engl J Med , vol.339 , pp. 1869-1874
    • McColl, K.1    Murray, L.2    El-Omar, E.3
  • 35
    • 0030825448 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori affects symptoms in non-ulcer dyspepsia
    • Gilvarry J, Buckley MJ, Beattie S, et al. Eradication of Helicobacter pylori affects symptoms in non-ulcer dyspepsia. Scand J Gastroenterol 1997; 32:535-540.
    • (1997) Scand J Gastroenterol , vol.32 , pp. 535-540
    • Gilvarry, J.1    Buckley, M.J.2    Beattie, S.3
  • 36
    • 0029920865 scopus 로고    scopus 로고
    • Long-term outcome of triple therapy in Helicobacter pylori-related nonulcer dyspepsia: A prospective controlled assessment
    • Sheu BS, Lin CY, Lin XZ, et al. Long-term outcome of triple therapy in Helicobacter pylori-related nonulcer dyspepsia: a prospective controlled assessment. Am J Gastroenterol 1996; 91:441-447.
    • (1996) Am J Gastroenterol , vol.91 , pp. 441-447
    • Sheu, B.S.1    Lin, C.Y.2    Lin, X.Z.3
  • 37
    • 0032564656 scopus 로고    scopus 로고
    • Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. Omeprazole plus clarithromycin and amoxicillin effect one year after treatment (OCAY) study group
    • Blum AL, Talley NJ, O'Morain C, et al. Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. Omeprazole plus clarithromycin and amoxicillin effect one year after treatment (OCAY) study group. N Engl J Med 1998; 339:1875-1881.
    • (1998) N Engl J Med , vol.339 , pp. 1875-1881
    • Blum, A.L.1    Talley, N.J.2    O'Morain, C.3
  • 38
    • 18944396858 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori for non-ulcer dyspepsia
    • Moayyedi P, Soo S, Deeks J, et al. Eradication of Helicobacter pylori for non-ulcer dyspepsia. Cochrane Database Syst Rev 2005; 25:CD002096. This well-done meta-analysis of 17 randomized controlled trials strongly suggests that H. pylori eradication may benefit a small subgroup of functional dyspepsia patients. Whether or not the widely advocated test and treat strategy is cost-effective remains to be seen.
    • (2005) Cochrane Database Syst Rev , vol.25
    • Moayyedi, P.1    Soo, S.2    Deeks, J.3
  • 39
    • 21144449754 scopus 로고    scopus 로고
    • Helicobacter pylori eradication does not cause reflux oesophagitis in functional dyspeptic patients: A randomized, investigator-blinded, placebo-controlled trial
    • Ott EA, Mazzoleni LE, Edelweiss MI, et al. Helicobacter pylori eradication does not cause reflux oesophagitis in functional dyspeptic patients: a randomized, investigator-blinded, placebo-controlled trial. Aliment Pharmacol Ther 2005; 21:1231-1239. Some years ago concern was raised that H. pylori eradication might lead to exacerbation of GERD or to de-novo development of GERD. This study helps to take some of the fear away.
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 1231-1239
    • Ott, E.A.1    Mazzoleni, L.E.2    Edelweiss, M.I.3
  • 40
    • 13944271427 scopus 로고    scopus 로고
    • Symptom-based outcome measures for dyspepsia and GERD trials: A systematic review
    • Fraser A, Delaney B, Moayyedi P. Symptom-based outcome measures for dyspepsia and GERD trials: a systematic review. Am J Gastroenterol 2005; 100:442-452. This review identified 26 disease-specific questionnaires for GERD, dyspepsia or both. Above all, this paper makes clear that there is a lack of consensus about which type of instrument is the most appropriate for clinical trials. The authors' recommendation that at least specific symptoms should be scored feels good, but whether this can be concluded from their review is debatable.
    • (2005) Am J Gastroenterol , vol.100 , pp. 442-452
    • Fraser, A.1    Delaney, B.2    Moayyedi, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.