Inhibition of calcineurin by infusion of CsA causes hyperphosphorylation of tau and is accompanied by abnormal behavior in mice

Biological Chemistry

Volumn 387, Issue 7, 2006, Pages 977-983

  Yu, Da Yu ^a   Luo, Jing ^a   Bu, Fan ^a   Song, Gao Jie ^a   Zhang, Lai Qun ^a,b   Wei, Qun ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

^b Shijiazhuang Pharmaceutical Company   (China)

Author keywords

Activity; Calcineurin; Cyclosporin A; Spatial memory; Tau

Indexed keywords

BRAIN EXTRACT; CALCINEURIN INHIBITOR; CYCLOSPORIN A; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; SERINE; TAU PROTEIN;

ABNORMAL BEHAVIOR; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN LATERAL VENTRICLE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME KINETICS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NEUROCHEMISTRY; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SPATIAL MEMORY;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BRAIN; CALCINEURIN; CYCLOSPORINE; KINETICS; MAZE LEARNING; MEMORY; MICE; PHOSPHORYLATION; TAU PROTEINS;

EID: 33746216555     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2006.121     Document Type: Conference Paper

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