Development of the high throughput screening assay for identification of agonists of an orphan nuclear receptor

Assay and Drug Development Technologies

Volumn 4, Issue 3, 2006, Pages 253-262

  Kapitskaya, Marianna ^a   Cunningham, Michael E ^a   Lacson, Raul ^a   Kornienko, Oleg ^a   Bednar, Bohumil ^a   Petrukhin, Konstantin ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; BETA LACTAMASE; CELL NUCLEUS RECEPTOR; ORPHAN NUCLEAR RECEPTOR; ORPHAN NUCLEAR RECEPTOR AGONIST; RECEPTOR STIMULATING AGENT; RECOMBINASE; RETINA SPECIFIC NUCLEAR RECEPTOR; THYROID HORMONE; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; BIOASSAY; CELL LINE; CHO CELL; CONTROLLED STUDY; DRUG IDENTIFICATION; ENERGY TRANSFER; FLUORESCENCE ACTIVATED CELL SORTING; GENE CONSTRUCT; GENETIC RECOMBINATION; GENETIC TRANSFECTION; GENOME; HIGH THROUGHPUT SCREENING; LIGAND BINDING; MAMMAL CELL; NONHUMAN; PHOTORECEPTOR CELL; PROTEIN EXPRESSION; REPORTER GENE; RETINA;

ANIMALS; BIOLOGICAL ASSAY; CHO CELLS; CRICETINAE; CRICETULUS; DRUG DESIGN; FLOW CYTOMETRY; PHARMACEUTICAL PREPARATIONS; PROTEIN INTERACTION MAPPING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS;

EID: 33746164400     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2006.4.253     Document Type: Article

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