Hypoglycaemic and antidiabetic effect of root extracts of Ceiba pentandra in normal and diabetic rats

African Journal of Traditional, Complementary and Alternative Medicines

Volumn 3, Issue 1, 2006, Pages 129-136

  Djomeni, Paul Désiré Dzeufiet ^a   Tédong, Léonard ^a   Asongalem, Emmanuel Acha ^a   Dimo, Théophile ^a   Sokeng, Selestin Dongmo ^b   Kamtchouing, Pierre ^a  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^b UNIVERSITY OF NGAOUNDERE   (Cameroon)

Author keywords

Ceiba pentandra; Diabetes mellitus; Hypoglycaemic; Plant extract

Indexed keywords

ANTIDIABETIC AGENT; CEIBA PENTANDRA EXTRACT; GLIBENCLAMIDE; GLUCOSE; INSULIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOMBACACEAE; CEIBA PENTANDRA; CONTROLLED STUDY; DIABETES MELLITUS; DOSE RESPONSE; DRUG MEGADOSE; GLUCOSE BLOOD LEVEL; GLUCOSE URINE LEVEL; LOW DRUG DOSE; MALE; MULTIPLE DRUG DOSE; NONHUMAN; PLANT ROOT; RAT; SINGLE DRUG DOSE; STATISTICAL SIGNIFICANCE; STREPTOZOCIN DIABETES;

EID: 33746154122     PISSN: 01896016     EISSN: 01896016     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Balkau B, Charles M. A and Eschwège, E. (2000) Discussion épidémiologique des nouveaux critères du dabète. Mt Endocrinologie 2: 229-34.
2. Cetto, A. A, Wiedenfeld, H, Revilla, M. C. and Sergio I. (2000). A. Hypoglycemic effect of Equisetum myriochaetum aerial parts on streptozotocin diabetic rats. J Ethnopharmacol 72: 129-33.
3. Djrolo, F, Houngbe, H, Avode, G, Addra, B, Kodjoh, N., Avinadje, M. and Monterio B. (1998). Le diabète lié à la mal nutrition (Diabète tropical). Médecine Afrique Noire 45 (8/9): 538-42.
4. Hosseinzadeh, H., Ramezani, M. and Danaei, A. R. (2002). Atihyperglicaemic effect and acute toxicity of Securigera securidaca L. seed extracts in mice. Phytoter Res. 2 16 (8):745-7.
5. Junod, A., Lambert, A. E, Stepfather, W. (1969), Renold AE. Diabetogenic action of streptozocin from dose to metabolic response. J Clin Invest. 48: 2129-39.
6. Jyoti, M., Vihas, T. V, Ravikumar, A. and Sarita, G. (2002). Glucose lowering effect of aqueous extract of Enicostemma Littorale Blume in diabetes: a possible mechanism of action. J Ethnopharmacol 81: 317-20.
7. Kameswara, R. B., Guiri, R., Kesavulu, M. M. and Apparao, C. H. (2001). Effect of oral administration of bark extracts of Pterocarpus santalinus L. on blood glucose level in experimental animals. J Ethnopharmacol 74: 69-74.
8. Kamtchouing, P., Sokeng, DS, Moundipa, F. P., Watcho, P., Jatsa, B. H. and Lontsi, D. (1998). Protective role of Anacardium Occidentale extract against streptozotocin - induced in rats. J Ethnopharmacol 62:55-99.
9. Marles, J. R. and Farnsworth, N. R. (1995). Antidiabetic plants and their active constituents. Phytomedicine 2 (2): 123-89.
10. Moller, D. E. (2001). New drug targets for type 2 diabetes and the metabolic syndrome. Nature 414: 821-27.
11. Ngounou, E. N., Meli, A. L., Lontsi, D., Sondengam, B.L., Atta-Ur Rahman., Choudhary, M. I., Malik, S. and Akhtar, F. (2000). New isoflavone from Ceiba pendandra. Phytochemestry 54: 107-110.
12. Noreen, Y., El-Seedi, H., Perera, P. and Bohlin, L. (1998). Two new isoflavones from Ceiba pendandra and their biosynthesis. J Nat Prod 61(1): 8-12.
13. Noumi, E. and Dibakto, T. W. (2000). Medicinal plants used for peptic ulcer in the Bangangté region, Western Cameroon. Fitotherapia 70: 406-12.
14. Noumi, E., Houngue, F. and Lontsi, D. (1999). Traditional medicines in primary health care: plants used for the treatment of hypertension in Bafia, Cameroon. Fitoterapia 70: 234-39.
15. Noumi, E. and Tchakonang, N. Y. C. (2001). Plants used as abortificients in the Sangmelima region of Southern Cameroon. J Ethnopharmacol 76: 263-68.
16. Olusola, L, Ike, C. O. and Mariam, S. (2003). Hypoglycaemic properties of aqueous bark extract of Ceiba pentandra in streptozotocin-induce diabetic rats. J Ethnopharmacol 84:139-142
17. Sharma, S. R, Dwivedi, S. K. and Swarup, D. (1997). Hypoglycaemic, antihyperglycaemic and hypolipidemic activities of Cesalpinia bounducella seed in rats. J Ethnopharmacol. 58: 39-44.
18. Shirwaikar, A., Rajendran, K., Dinesh Kumar, C, and Rangopal Bodla. (2004). Antidiabetic activity of aqueous leave extract of Annona squamosa in streptozotocin-nicotinamide type 2 diabetic rats. J Ethnopharmacol. 91(1):171-5.
19. Szkudelski, T. (2001). The mechanism of Alloxan and streptozotocin Action in β cells of the rats pancreas. Physiol Res. 50: 536-46.
20. Ueda, H., Kaneda, N., Kawanishi, K., Alves, S. M. and Moriyasu, M. (2002). A new isoflavone glycoside from Ceiba pentandra (L.). Gaertner. Chem Pharm Bull 50 (3): 403-4.
21. WHO. (1999). Diabetes mellitus. Fact sheet number 138 and 236, Geneva.
22. WHO. (2002). WHO launches the first global strategy on traditional medicine: Press release WHO/38.