Thienocinnolinone alkanoic acid derivatives as aldose reductase inhibitors

Medicinal Chemistry

Volumn 2, Issue 1, 2006, Pages 39-45

  Pau, A ^a   Asproni, B ^a   Murineddu, G ^a   Boatto, G ^a   Grella, G E ^a   Rakowitz, D ^b   Costantino, L ^c   Pinna, G A ^a  

^a UNIVERSITY OF SASSARI   (Italy)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Aldose reductase inhibitors; Carboxylic acids; Diabetic complications; Thieno h cinnolinone

Indexed keywords

6 (5 CHLORO 3 METHYLBENZOFURAN 2 SULFONYL) 2H PYRIDAZIN 3 ONE; 8 CHLORO 4,4A,5,6 TETRAHYDROTHIENO[2,3 H]CINNOLIN 3(2H) ONE 2 HEXANOIC ACID; ACETIC ACID DERIVATIVE; ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; ALKANOIC ACID; ALRESTATIN; CARBOXYLIC ACID; EPALRESTAT; HEXANOIC ACID DERIVATIVE; MINALRESTAT; PYRIDAZINE DERIVATIVE; SORBINIL; TOLRESTAT; UNCLASSIFIED DRUG; ZOPOLRESTAT;

ANIMAL TISSUE; ARTICLE; COW; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; LENS; NONHUMAN; PRIORITY JOURNAL;

ALDEHYDE REDUCTASE; ANIMALS; CARBOXYLIC ACIDS; CATTLE; ENZYME INHIBITORS; LENS, CRYSTALLINE; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 33746140893     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340606775197769     Document Type: Article

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