Discovery of potential sorbitol dehydrogenase inhibitors from virtual screening

Medicinal Chemistry

Volumn 2, Issue 3, 2006, Pages 239-242

  Darmanin, Connie ^a   Iwata, Takeshi ^b   Carper, Deborah A ^c   El Kabbani, Ossama ^a  

^a MONASH UNIVERSITY   (Australia)

^b NATIONAL HOSPITAL ORGANIZATION TOKYO MEDICAL CENTER   (Japan)

^c NATIONAL EYE INSTITUTE   (United States)

Author keywords

DOCK program; NCI database; SDH inhibitor; Spectrophotometer; Zn atom

Indexed keywords

1H INDOLE 2,3 DIONE 5 BROMO 6 NITRO 1 (2,3,4 TRI O ACETYL ALPHA LEVO ARABINOPYRANOSYL) (9 CHLORIDE); 2 HYDROXYMETHYL 4 (4' N,N DIMETHYLAMINOSULFONYL 1 PIPERAZINO)PYRAMIDINE; 3 HYDROXY 2 NAPTHOIC (2 HYDROXYBENZYLIDENE)HYDRAZIDE; CYSTEIC ACID; FLAVINE ADENINE NUCLEOTIDE; FLAVINE ADENINE NUCLEOTIDE DISODIUM HYDRATE; FOLIC ACID; GLUCOSE; HYDRAZIDE DERIVATIVE; IDITOL DEHYDROGENASE; IDITOL DEHYDROGENASE INHIBITOR; INDOLE DERIVATIVE; METHOTREXATE; N 2,4 DINITROPHENYL LEVO CYSTEIC ACID; OXIDOREDUCTASE INHIBITOR; POLYOL; PYRIDINE DERIVATIVE; SDI 158; UNCLASSIFIED DRUG; VANILLIN DERIVATIVE; VANILLINAZINE;

ARTICLE; COMPUTER PROGRAM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; GLUCOSE METABOLISM; IC 50; MOLECULAR MODEL; PREDICTION; PRIORITY JOURNAL;

DATABASE MANAGEMENT SYSTEMS; ENZYME INHIBITORS; L-IDITOL 2-DEHYDROGENASE; MODELS, MOLECULAR;

EID: 33746125727     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340606776930772     Document Type: Article

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