Crystal structure of sorbitol dehydrogenase

Chemico-Biological Interactions

Volumn 130-132, Issue , 2001, Pages 351-358

  Johansson, Kenth ^a   El Ahmad, Mustafa ^a,b   Kaiser, Christina ^b   Jörnvall, Hans ^b   Eklund, Hans ^a   Höög, Jan Olov ^b   Ramaswamy, S ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

NADH; Polyol pathway; Sorbitol binding site; Tetrameric dehydrogenase; Zn enzyme

Indexed keywords

ALCOHOL DEHYDROGENASE; DIMER; IDITOL DEHYDROGENASE; POLYOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SORBITOL; TETRAMER; ZINC ION;

CLOSTRIDIUM BEIJERINCKII; COENZYME; CONFERENCE PAPER; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SUBUNIT; HYDROGEN BOND; MAMMAL; NONHUMAN; RAT; SEQUENCE HOMOLOGY;

ANIMALS; CATALYTIC DOMAIN; COENZYMES; CRYSTALLOGRAPHY, X-RAY; L-IDITOL 2-DEHYDROGENASE; MODELS, MOLECULAR; NAD; PROTEIN CONFORMATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS; RATS; SUBSTRATE SPECIFICITY; ZINC;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 17444437443     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(00)00260-X     Document Type: Conference Paper

References (10)

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5. Modelling studies on the binding of sustrate and inhibitor to the active site of human sorbitol dehydrogenase
6. Zinc environment in sheep liver sorbitol dehydrogenase
7. Cobalt(II)-substituted class III alcohol and sorbitol dehydrogenases from human liver
8. Zinc coordination in mammalian sorbitol dehydrogenase: Replacement of putative zinc ligands by site-directed mutagenesis
9. On the role of Glu-68 in alcohol dehydrogenase
10. NADP-dependent bacterial alcohol dehydrogenases: Crystal structure, cofactor-binding and cofactor specificity of the ADHs of Clostridium beijerinckii and Thermoanaerobacter brockii