-
1
-
-
22344446049
-
Analysis of the in vivo functions of Mrp3
-
Belinsky MG, Dawson PA, Shchaveleva I, Bain LJ, Wang R, Ling V, Chen ZS, Grinberg A, Westphal H, Klein-Szanto A, et al. (2005) Analysis of the in vivo functions of Mrp3. Mol Pharmacol 68:160-168.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 160-168
-
-
Belinsky, M.G.1
Dawson, P.A.2
Shchaveleva, I.3
Bain, L.J.4
Wang, R.5
Ling, V.6
Chen, Z.S.7
Grinberg, A.8
Westphal, H.9
Klein-Szanto, A.10
-
2
-
-
0040761368
-
cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats
-
Buchler M, König J, Brom M, Kartenbeck J, Spring H, Horie T, and Keppler D (1996) cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats. J Biol Chem 271:15091-15098.
-
(1996)
J Biol Chem
, vol.271
, pp. 15091-15098
-
-
Buchler, M.1
König, J.2
Brom, M.3
Kartenbeck, J.4
Spring, H.5
Horie, T.6
Keppler, D.7
-
3
-
-
0023545356
-
Decreased production of glutathione in patients with cirrhosis
-
Burgunder JM and Lauterburg BH (1987) Decreased production of glutathione in patients with cirrhosis. Eur J Clin Investig 17:408-414.
-
(1987)
Eur J Clin Investig
, vol.17
, pp. 408-414
-
-
Burgunder, J.M.1
Lauterburg, B.H.2
-
4
-
-
0034671784
-
Quantitative and qualitative gender-related differences in jejunal glutathione S-transferase in the rat: Effect of testosterone administration
-
Catania V, Luquita M, Sánchez Pozzi E, and Mottino A (2000) Quantitative and qualitative gender-related differences in jejunal glutathione S-transferase in the rat: effect of testosterone administration. Life Sci 68:467-474.
-
(2000)
Life Sci
, vol.68
, pp. 467-474
-
-
Catania, V.1
Luquita, M.2
Sánchez Pozzi, E.3
Mottino, A.4
-
5
-
-
6944241732
-
Co-regulation of expression of phase II metabolizing enzymes and multidrug resistance-associated protein 2
-
Catania VA, Sánchez Pozzi EJ, Luquita MG, Ruiz ML, Villanueva SSM, Jones B, and Mottino AD (2004) Co-regulation of expression of phase II metabolizing enzymes and multidrug resistance-associated protein 2. Ann Hepatol 3:11-17.
-
(2004)
Ann Hepatol
, vol.3
, pp. 11-17
-
-
Catania, V.A.1
Sánchez Pozzi, E.J.2
Luquita, M.G.3
Ruiz, M.L.4
Villanueva, S.S.M.5
Jones, B.6
Mottino, A.D.7
-
6
-
-
0024432603
-
Regulation of cellular glutathione
-
Deneke SM and Fanburg BL (1989) Regulation of cellular glutathione. Am J Physiol 257:L163-L173.
-
(1989)
Am J Physiol
, vol.257
-
-
Deneke, S.M.1
Fanburg, B.L.2
-
7
-
-
1642316825
-
Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat
-
Denk GU, Soroka CJ, Takeyama Y, Chen WS, Schuetz JD, and Boyer JL (2004) Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat. J Hepatol 40:585-591.
-
(2004)
J Hepatol
, vol.40
, pp. 585-591
-
-
Denk, G.U.1
Soroka, C.J.2
Takeyama, Y.3
Chen, W.S.4
Schuetz, J.D.5
Boyer, J.L.6
-
8
-
-
0036329226
-
Organ-specific alterations in RAR alpha:RXR alpha abundance regulate rat Mrp2 (Abcc2) expression in obstructive cholestasis
-
Denson LA, Bohan A, Held MA, and Boyer JL (2002) Organ-specific alterations in RAR alpha:RXR alpha abundance regulate rat Mrp2 (Abcc2) expression in obstructive cholestasis. Gastroenterology 123:599-607.
-
(2002)
Gastroenterology
, vol.123
, pp. 599-607
-
-
Denson, L.A.1
Bohan, A.2
Held, M.A.3
Boyer, J.L.4
-
9
-
-
1842479142
-
Consequences of bile duct obstruction on intestinal expression and function of multidrug resistance-associated protein 2
-
Dietrich C, Geier A, Salein N, Lammert F, Roeb E, Oude Elferink RP, Matern S, and Gartung C (2004) Consequences of bile duct obstruction on intestinal expression and function of multidrug resistance-associated protein 2. Gastroenterology 126:1044-1053.
-
(2004)
Gastroenterology
, vol.126
, pp. 1044-1053
-
-
Dietrich, C.1
Geier, A.2
Salein, N.3
Lammert, F.4
Roeb, E.5
Oude Elferink, R.P.6
Matern, S.7
Gartung, C.8
-
10
-
-
0034928631
-
Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver
-
Donner MG and Keppler D (2001) Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver. Hepatology 34:351-359.
-
(2001)
Hepatology
, vol.34
, pp. 351-359
-
-
Donner, M.G.1
Keppler, D.2
-
11
-
-
0030027622
-
Down-regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis
-
Gartung C, Ananthanarayanan M, Rahman MA, Schuele S, Nundy S, Soroka CJ, Stolz A, Suchy FL, and Boyer JL (1996) Down-regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis. Gastroenterology 110:199-209.
-
(1996)
Gastroenterology
, vol.110
, pp. 199-209
-
-
Gartung, C.1
Ananthanarayanan, M.2
Rahman, M.A.3
Schuele, S.4
Nundy, S.5
Soroka, C.J.6
Stolz, A.7
Suchy, F.L.8
Boyer, J.L.9
-
12
-
-
0033958156
-
Involvement of an organic anion transporter (canalicular multispecific organic anion transporter/multidrug resistance-associated protein 2) in gastrointestinal secretion of glutathione conjugates in rats
-
Gotoh Y, Suzuki H, Kinoshita S, Hirohashi T, Kato Y, and Sugiyama Y (2000) Involvement of an organic anion transporter (canalicular multispecific organic anion transporter/multidrug resistance-associated protein 2) in gastrointestinal secretion of glutathione conjugates in rats. J Pharmacol Exp Ther 292:433-439.
-
(2000)
J Pharmacol Exp Ther
, vol.292
, pp. 433-439
-
-
Gotoh, Y.1
Suzuki, H.2
Kinoshita, S.3
Hirohashi, T.4
Kato, Y.5
Sugiyama, Y.6
-
13
-
-
0019167355
-
Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
-
Griffith OW (1980) Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal Biochem 106:207-221.
-
(1980)
Anal Biochem
, vol.106
, pp. 207-221
-
-
Griffith, O.W.1
-
14
-
-
0033984880
-
P-glycoprotein- and mrp2-mediated octreotide transport in renal proximal tubule
-
Gutmann H, Miller DS, Droulle A, Drewe J, Fahr A, and Fricker G (2000) P-glycoprotein- and mrp2-mediated octreotide transport in renal proximal tubule. Br J Pharmacol 129:251-256.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 251-256
-
-
Gutmann, H.1
Miller, D.S.2
Droulle, A.3
Drewe, J.4
Fahr, A.5
Fricker, G.6
-
15
-
-
0016275313
-
Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
-
Habig WH, Pabst MJ, and Jakoby WB (1974) Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130-7139.
-
(1974)
J Biol Chem
, vol.249
, pp. 7130-7139
-
-
Habig, W.H.1
Pabst, M.J.2
Jakoby, W.B.3
-
16
-
-
0029561598
-
The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
-
Hayes JD and Pulford DJ (1995) The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 30:445-600.
-
(1995)
Crit Rev Biochem Mol Biol
, vol.30
, pp. 445-600
-
-
Hayes, J.D.1
Pulford, D.J.2
-
17
-
-
0025888299
-
Intrahepatic conversion of a glutathione conjugate to its mercapturic acid. Metabolism of 1-chloro-2,4-dinitrobenzene in isolated perfused rat and guinea pig livers
-
Hinchman CA, Matsumoto H, Simmons TW, and Ballatori N (1991) Intrahepatic conversion of a glutathione conjugate to its mercapturic acid. Metabolism of 1-chloro-2,4-dinitrobenzene in isolated perfused rat and guinea pig livers. J Biol Chem 266:22179-22185.
-
(1991)
J Biol Chem
, vol.266
, pp. 22179-22185
-
-
Hinchman, C.A.1
Matsumoto, H.2
Simmons, T.W.3
Ballatori, N.4
-
18
-
-
0033774170
-
Recent advances in bilirubin metabolism research: The molecular mechanism of hepatocyte bilirubin transport and its clinical relevance
-
Kamisako T, Kobayashi Y, Takeuchi K, Ishihara T, Higuchi K, Tanaka Y, Gabazza EC, and Adachi Y (2000) Recent advances in bilirubin metabolism research: the molecular mechanism of hepatocyte bilirubin transport and its clinical relevance. J Gastroenterol 35:659-664.
-
(2000)
J Gastroenterol
, vol.35
, pp. 659-664
-
-
Kamisako, T.1
Kobayashi, Y.2
Takeuchi, K.3
Ishihara, T.4
Higuchi, K.5
Tanaka, Y.6
Gabazza, E.C.7
Adachi, Y.8
-
19
-
-
0034099587
-
Localization, substrate specificity and drug resistance conferred by conjugated export pump of the MRP family
-
Keppler D, Kamisako T, Leier I, Cui Y, Nies AT, Tsuji H, and Konig J (2000) Localization, substrate specificity and drug resistance conferred by conjugated export pump of the MRP family. Adv Enzyme Regul 40:339-349.
-
(2000)
Adv Enzyme Regul
, vol.40
, pp. 339-349
-
-
Keppler, D.1
Kamisako, T.2
Leier, I.3
Cui, Y.4
Nies, A.T.5
Tsuji, H.6
Konig, J.7
-
20
-
-
0035207243
-
Adaptive regulation of bile salt transporters in kidney and liver in obstructive cholestasis in the rat
-
Lee J, Azzaroli F, Wang L, Soroka CJ, Gigliozzi A, Setchell KDR, Kramer W, and Boyer JL (2001) Adaptive regulation of bile salt transporters in kidney and liver in obstructive cholestasis in the rat. Gastroenterology 121:1473-1484.
-
(2001)
Gastroenterology
, vol.121
, pp. 1473-1484
-
-
Lee, J.1
Azzaroli, F.2
Wang, L.3
Soroka, C.J.4
Gigliozzi, A.5
Setchell, K.D.R.6
Kramer, W.7
Boyer, J.L.8
-
22
-
-
0021349075
-
Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver
-
Meier PJ, Sztul ES, Reuben A, and Boyer JL (1984) Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver. J Cell Biol 98:991-1000.
-
(1984)
J Cell Biol
, vol.98
, pp. 991-1000
-
-
Meier, P.J.1
Sztul, E.S.2
Reuben, A.3
Boyer, J.L.4
-
23
-
-
0034978930
-
Expression of multidrug resistance-associated protein 2 in small intestine from pregnant and postpartum rats
-
Mottino AD, Hoffman T, Jennes L, Cao J, and Vore M (2001) Expression of multidrug resistance-associated protein 2 in small intestine from pregnant and postpartum rats. Am J Physiol 280:G1261-G1273.
-
(2001)
Am J Physiol
, vol.280
-
-
Mottino, A.D.1
Hoffman, T.2
Jennes, L.3
Cao, J.4
Vore, M.5
-
24
-
-
0034119967
-
Expression and localization of multidrug resistant protein mrp2 in rat small intestine
-
Mottino AD, Hoffman T, Jennes L, and Vore M (2000) Expression and localization of multidrug resistant protein mrp2 in rat small intestine. J Pharmacol Exp Ther 293:717-723.
-
(2000)
J Pharmacol Exp Ther
, vol.293
, pp. 717-723
-
-
Mottino, A.D.1
Hoffman, T.2
Jennes, L.3
Vore, M.4
-
25
-
-
0026072857
-
Mechanisms and regulation of bile secretion
-
Nathanson MH and Boyer JL (1991) Mechanisms and regulation of bile secretion. Hepatology 14:551-566.
-
(1991)
Hepatology
, vol.14
, pp. 551-566
-
-
Nathanson, M.H.1
Boyer, J.L.2
-
26
-
-
0027177238
-
p-Aminohippurate transport in rat renal brush border membranes: A potential sensitive transport system and an anion exchanger
-
Ohoka K, Takano M, and Okano T (1993) p-Aminohippurate transport in rat renal brush border membranes: a potential sensitive transport system and an anion exchanger. Biol Pharm Bull 16:395-401.
-
(1993)
Biol Pharm Bull
, vol.16
, pp. 395-401
-
-
Ohoka, K.1
Takano, M.2
Okano, T.3
-
27
-
-
0027238833
-
Constitutive and inducible profile of glutathione S-transferase subunits in biliary epithelial cells and hepatocytes isolated from rat liver
-
Parola M, Biocca ME, Leonarduzzi G, Albano E, Dianzani MU, Gilmore KS, Meyer DL, Ketterer B, Slater TF, and Cheeseman KH (1993) Constitutive and inducible profile of glutathione S-transferase subunits in biliary epithelial cells and hepatocytes isolated from rat liver. Biochem J 291:641-647.
-
(1993)
Biochem J
, vol.291
, pp. 641-647
-
-
Parola, M.1
Biocca, M.E.2
Leonarduzzi, G.3
Albano, E.4
Dianzani, M.U.5
Gilmore, K.S.6
Meyer, D.L.7
Ketterer, B.8
Slater, T.F.9
Cheeseman, K.H.10
-
28
-
-
0029981430
-
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
-
Paulusma CC, Bosma PJ, Zaman GJ, Bakker CT, Otter M, Scheffer GL, Scheper RJ, Borst P, and Oude Elferink RP (1996) Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science (Wash DC) 271:1126-1128.
-
(1996)
Science (Wash DC)
, vol.271
, pp. 1126-1128
-
-
Paulusma, C.C.1
Bosma, P.J.2
Zaman, G.J.3
Bakker, C.T.4
Otter, M.5
Scheffer, G.L.6
Scheper, R.J.7
Borst, P.8
Oude Elferink, R.P.9
-
29
-
-
0036890295
-
Increase in renal glutathione in cholestatic liver disease is due to a direct effect of bile acids
-
Purucker E, Marschall H-U, Geier A, Gartung C, and Matern S (2002) Increase in renal glutathione in cholestatic liver disease is due to a direct effect of bile acids. Am J Physiol 283:F1281-F1289.
-
(2002)
Am J Physiol
, vol.283
-
-
Purucker, E.1
Marschall, H.-U.2
Geier, A.3
Gartung, C.4
Matern, S.5
-
30
-
-
0029096381
-
Glutathione in plasma, liver and kidney in the development of CCl4-induced cirrhosis of the rat
-
Purucker E, Wernze H, and Krandik G (1995) Glutathione in plasma, liver and kidney in the development of CCl4-induced cirrhosis of the rat. Res Exp Med 195:193-200.
-
(1995)
Res Exp Med
, vol.195
, pp. 193-200
-
-
Purucker, E.1
Wernze, H.2
Krandik, G.3
-
31
-
-
0036080426
-
Expression and localization of the multidrug resistance-associated protein 3 in rat small and large intestine
-
Rost D, Mahner S, Sugiyama Y, and Stremmel W (2002) Expression and localization of the multidrug resistance-associated protein 3 in rat small and large intestine. Am J Physiol 282:G720-G726.
-
(2002)
Am J Physiol
, vol.282
-
-
Rost, D.1
Mahner, S.2
Sugiyama, Y.3
Stremmel, W.4
-
32
-
-
0030832802
-
Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules
-
Schaub TP, Kartenbeck J, Konig J, Vogel O, Witzgall R, Kriz W, and Keppler D (1997) Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules. J Am Soc Nephrol 8:1213-1221.
-
(1997)
J Am Soc Nephrol
, vol.8
, pp. 1213-1221
-
-
Schaub, T.P.1
Kartenbeck, J.2
Konig, J.3
Vogel, O.4
Witzgall, R.5
Kriz, W.6
Keppler, D.7
-
33
-
-
0002960833
-
Preparation of microsomes and submicrosomal fractions
-
Siekevitz P (1962) Preparation of microsomes and submicrosomal fractions. Methods Enzymol 5:61-68.
-
(1962)
Methods Enzymol
, vol.5
, pp. 61-68
-
-
Siekevitz, P.1
-
34
-
-
0035080391
-
Cellular localization and up-regulation of multidrug resistance- associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver
-
Soroka CJ, Lee JM, Azzaroli F, and Boyer JL (2001) Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver. Hepatology 33:783-791.
-
(2001)
Hepatology
, vol.33
, pp. 783-791
-
-
Soroka, C.J.1
Lee, J.M.2
Azzaroli, F.3
Boyer, J.L.4
-
35
-
-
0036080423
-
Increased renal expression of bilirubin glucuronide transporters in a rat model of obstructive jaundice
-
Tanaka Y, Kobayashi Y, Garbazza E, Higuchi K, Kamisako T, Kuroda M, Takeuchi K, Iwasa K, Kaito M, and Adachi Y (2002) Increased renal expression of bilirubin glucuronide transporters in a rat model of obstructive jaundice. Am J Physiol 282:G656-G662.
-
(2002)
Am J Physiol
, vol.282
-
-
Tanaka, Y.1
Kobayashi, Y.2
Garbazza, E.3
Higuchi, K.4
Kamisako, T.5
Kuroda, M.6
Takeuchi, K.7
Iwasa, K.8
Kaito, M.9
Adachi, Y.10
-
36
-
-
0037357689
-
Role of BSP/Bilirubin binding protein on p-aminohippurate transport in rat kidney
-
Torres AM, MacLaughlin M, Quaglia N, and Stremmel W (2003) Role of BSP/Bilirubin binding protein on p-aminohippurate transport in rat kidney. Mol Cell Biochem 245:149-156.
-
(2003)
Mol Cell Biochem
, vol.245
, pp. 149-156
-
-
Torres, A.M.1
MacLaughlin, M.2
Quaglia, N.3
Stremmel, W.4
-
37
-
-
0030963906
-
The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis
-
Trauner M, Arrese M, Soroka CJ, Ananthanarayanan M, Koeppel T, Schlosser S, Suchy F, Keppler D, and Boyer JL (1997) The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis. Gastroenterology 113:255-264.
-
(1997)
Gastroenterology
, vol.113
, pp. 255-264
-
-
Trauner, M.1
Arrese, M.2
Soroka, C.J.3
Ananthanarayanan, M.4
Koeppel, T.5
Schlosser, S.6
Suchy, F.7
Keppler, D.8
Boyer, J.L.9
-
38
-
-
14844297355
-
Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats
-
Villanueva S, Ruiz M, Luquita M, Sánchez Pozzi E, Catania V, and Mottino A (2005) Involvement of Mrp2 in hepatic and intestinal disposition of dinitrophenyl-S-glutathione in partially hepatectomized rats. Toxicol Sci 84:4-11.
-
(2005)
Toxicol Sci
, vol.84
, pp. 4-11
-
-
Villanueva, S.1
Ruiz, M.2
Luquita, M.3
Sánchez Pozzi, E.4
Catania, V.5
Mottino, A.6
-
39
-
-
0031738416
-
Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and downregulation of the organic anion transporter, Mrp2 and the bile salt transporter, Spgp, in endotoxemic rat liver
-
Vos TA, Hooiveld GJ, Koning H, Childs S, Meijer DK, Moshage H, Jansen PL, and Muller M (1998) Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and downregulation of the organic anion transporter, Mrp2 and the bile salt transporter, Spgp, in endotoxemic rat liver. Hepatology 28:1637-1644.
-
(1998)
Hepatology
, vol.28
, pp. 1637-1644
-
-
Vos, T.A.1
Hooiveld, G.J.2
Koning, H.3
Childs, S.4
Meijer, D.K.5
Moshage, H.6
Jansen, P.L.7
Muller, M.8
-
40
-
-
0015919572
-
Intestinal epithelial cell surface membrane glycoprotein synthesis
-
Weiser MM (1973) Intestinal epithelial cell surface membrane glycoprotein synthesis. J Biol Chem 248:2536-2541.
-
(1973)
J Biol Chem
, vol.248
, pp. 2536-2541
-
-
Weiser, M.M.1
|