-
1
-
-
20344398197
-
Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling
-
Ai, M., Holmen, S. L., Van Hul, W., Williams, B. O. and Warman, M. L. (2005). Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling. Mol. Cell. Biol. 25, 4946-4955.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 4946-4955
-
-
Ai, M.1
Holmen, S.L.2
Van Hul, W.3
Williams, B.O.4
Warman, M.L.5
-
2
-
-
0034933057
-
Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow
-
Bafico, A., Liu, G., Yaniv, A., Gazit, A. and Aaronson, S. A. (2001). Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat. Cell Biol. 3, 683-686.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 683-686
-
-
Bafico, A.1
Liu, G.2
Yaniv, A.3
Gazit, A.4
Aaronson, S.A.5
-
3
-
-
0037163113
-
Regulation of Wnt signaling during adipogenesis
-
Bennett, C. N., Ross, S. E., Longo, K. A., Bajnok, L., Hemati, N., Johnson, K. W., Harrison, S. D. and MacDougald, O. A. (2002). Regulation of Wnt signaling during adipogenesis. J. Biol. Chem. 277, 30998-31004.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30998-31004
-
-
Bennett, C.N.1
Ross, S.E.2
Longo, K.A.3
Bajnok, L.4
Hemati, N.5
Johnson, K.W.6
Harrison, S.D.7
MacDougald, O.A.8
-
4
-
-
0037118285
-
High bone density due to a mutation in LDL-receptor-related protein 5
-
Boyden, L. M., Mao, J., Belsky, J., Mitzner, L., Farhi, A., Mitnick, M. A., Wu, D., Insogna, K. and Lifton, R. P. (2002). High bone density due to a mutation in LDL-receptor-related protein 5. N. Engl. J. Med. 346, 1513-1521.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1513-1521
-
-
Boyden, L.M.1
Mao, J.2
Belsky, J.3
Mitzner, L.4
Farhi, A.5
Mitnick, M.A.6
Wu, D.7
Insogna, K.8
Lifton, R.P.9
-
5
-
-
0035798069
-
GSK-3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and beta-catenin stabilisation without elevation of glycogen synthase activity
-
Culbert, A. A., Brown, M. J., Frame, S., Hagen, T., Cross, D. A., Bax, B. and Reith, A. D. (2001). GSK-3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and beta-catenin stabilisation without elevation of glycogen synthase activity. FEBS Lett. 507, 288-294.
-
(2001)
FEBS Lett.
, vol.507
, pp. 288-294
-
-
Culbert, A.A.1
Brown, M.J.2
Frame, S.3
Hagen, T.4
Cross, D.A.5
Bax, B.6
Reith, A.D.7
-
6
-
-
0036927738
-
Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning
-
Davidson, G., Mao, B., del Barra Barrantes, I. and Niehrs, C. (2002). Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning. Development 129. 5587-5596.
-
(2002)
Development
, vol.129
, pp. 5587-5596
-
-
Davidson, G.1
Mao, B.2
del Barra Barrantes, I.3
Niehrs, C.4
-
7
-
-
18044386744
-
LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
-
Gong, Y., Slee, R. B., Fukai, N., Rawadi, G., Roman-Roman, S., Reginato, A. M., Wang, H., Cundy, T., Glorieux, F. H., Lev, D. et al. (2001). LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development, Cell 107, 513-523.
-
(2001)
Cell
, vol.107
, pp. 513-523
-
-
Gong, Y.1
Slee, R.B.2
Fukai, N.3
Rawadi, G.4
Roman-Roman, S.5
Reginato, A.M.6
Wang, H.7
Cundy, T.8
Glorieux, F.H.9
Lev, D.10
-
8
-
-
0042346318
-
The Wnt signaling inhibitor dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow
-
Gregory, C. A., Singh, H., Perry, A. S. and Prockop, D. J. (2003). The Wnt signaling inhibitor dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow. J. Biol. Chem. 278, 28067-28078.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 28067-28078
-
-
Gregory, C.A.1
Singh, H.2
Perry, A.S.3
Prockop, D.J.4
-
9
-
-
0036295950
-
Characterisation of the phosphorylation of beta-catenin at the GSK-3 priming site Ser45
-
Hagen, T. and Vidal-Puig, A. (2002). Characterisation of the phosphorylation of beta-catenin at the GSK-3 priming site Ser45. Biochem. Biophys. Res. Commun. 294, 324-328.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.294
, pp. 324-328
-
-
Hagen, T.1
Vidal-Puig, A.2
-
10
-
-
2342477161
-
Signalling activity of beta-catenin targeted to different subcellular compartments
-
Hagen, T., Sethi, J. K., Foxwell, N. and Vidal-Puig, A. (2004). Signalling activity of beta-catenin targeted to different subcellular compartments. Biochem. J. 379, 471-477.
-
(2004)
Biochem. J.
, vol.379
, pp. 471-477
-
-
Hagen, T.1
Sethi, J.K.2
Foxwell, N.3
Vidal-Puig, A.4
-
11
-
-
0036714307
-
Secreted Frizzled-related proteins: Searching for relationships and patterns
-
Jones, S. E. and Jomary, C. (2002). Secreted Frizzled-related proteins: searching for relationships and patterns. BioEssays 24, 811-820.
-
(2002)
BioEssays
, vol.24
, pp. 811-820
-
-
Jones, S.E.1
Jomary, C.2
-
12
-
-
0038783316
-
Secreted antagonists of the Wnt signalling pathway
-
Kawano, Y. and Kypta, R. (2003). Secreted antagonists of the Wnt signalling pathway. J. Cell Sci. 116, 2627-2634.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 2627-2634
-
-
Kawano, Y.1
Kypta, R.2
-
13
-
-
1642564590
-
Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis
-
Laudes, M., Christodoulides, C., Sewter, C., Rochford, J. J., Considine, R. V., Sethi, J. K., Vidal-Puig, A. and O'Rahilly, S. (2004). Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis. J. Biol. Chem. 279, 11711-11718.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 11711-11718
-
-
Laudes, M.1
Christodoulides, C.2
Sewter, C.3
Rochford, J.J.4
Considine, R.V.5
Sethi, J.K.6
Vidal-Puig, A.7
O'Rahilly, S.8
-
14
-
-
0036138175
-
A mutation in the LDL receptor-related protein 5 gene results in the amosomal dominant high-bonemass trait
-
Little, R. D., Carulli, J. P., Del Mastro, R. G., Dupuis, J., Osborne, M., Folz, C., Manning, S. P., Swain, P. M., Zhao, S. C., Eustace, B. et al. (2002). A mutation in the LDL receptor-related protein 5 gene results in the amosomal dominant high-bonemass trait. Am. J. Hum. Genet. 70, 11-19.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 11-19
-
-
Little, R.D.1
Carulli, J.P.2
Del Mastro, R.G.3
Dupuis, J.4
Osborne, M.5
Folz, C.6
Manning, S.P.7
Swain, P.M.8
Zhao, S.C.9
Eustace, B.10
-
15
-
-
8444251784
-
The Writ signaling pathway in development and disease
-
Logan, C. Y. and Nusse, R. (2004). The Writ signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20, 781-810.
-
(2004)
Annu. Rev. Cell Dev. Biol.
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
16
-
-
4143115909
-
Wntl0b inhibits development of white and brown adipose tissues
-
Longo, K. A., Wright, W. S., Kang, S., Gerin, I., Chiang, S. H., Lucas, P. C., Opp, M. R. and MacDougald, O. A. (2004). Wntl0b inhibits development of white and brown adipose tissues. J. Biol. Chem. 279, 35503-35509.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 35503-35509
-
-
Longo, K.A.1
Wright, W.S.2
Kang, S.3
Gerin, I.4
Chiang, S.H.5
Lucas, P.C.6
Opp, M.R.7
MacDougald, O.A.8
-
17
-
-
2342436339
-
Hypomorphic expression of Dkk1 in the doubleridge mouse: Dose dependence and compensatory interactions with Lrp6
-
MacDonald, B. T., Adamska, M. and Meisler, M. H. (2004). Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6. Development 131, 2543-2552.
-
(2004)
Development
, vol.131
, pp. 2543-2552
-
-
MacDonald, B.T.1
Adamska, M.2
Meisler, M.H.3
-
19
-
-
0037413696
-
Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling
-
Mao, B. and Niehrs, C. (2003). Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling. Gene 302, 179-183.
-
(2003)
Gene
, vol.302
, pp. 179-183
-
-
Mao, B.1
Niehrs, C.2
-
20
-
-
0035902050
-
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
-
Mao, B., Wu, W., Li, Y., Hoppe, D., Stannek, P., Glinka, A. and Niehrs, C. (2001). LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 411, 321-325.
-
(2001)
Nature
, vol.411
, pp. 321-325
-
-
Mao, B.1
Wu, W.2
Li, Y.3
Hoppe, D.4
Stannek, P.5
Glinka, A.6
Niehrs, C.7
-
21
-
-
0037030681
-
Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling
-
Mao, B., Wu, W., Davidson, G., Marhold, J., Li, M., Mechler, B. M., Delius, H., Hoppe, D., Stannek, P., Walter, C. et al. (2002). Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling. Nature 417, 664-667.
-
(2002)
Nature
, vol.417
, pp. 664-667
-
-
Mao, B.1
Wu, W.2
Davidson, G.3
Marhold, J.4
Li, M.5
Mechler, B.M.6
Delius, H.7
Hoppe, D.8
Stannek, P.9
Walter, C.10
-
22
-
-
0036153448
-
The Wnts
-
REVIEWS3001
-
Miller, J. R. (2002). The Wnts. Genome Biol. 3, REVIEWS3001.
-
(2002)
Genome Biol.
, vol.3
-
-
Miller, J.R.1
-
23
-
-
0347986626
-
Peroxisome-proliferator-activated receptor gamma suppresses Wnt /beta-catenin signalling during adipogenesis
-
Moldes, M., Zuo, Y., Morrison, R. F., Silva, D., Park, B. H., Liu, J. and Farmer, S.R. (2003). Peroxisome-proliferator-activated receptor gamma suppresses Wnt/beta-catenin signalling during adipogenesis. Biochem. J. 376, 607-613.
-
(2003)
Biochem. J.
, vol.376
, pp. 607-613
-
-
Moldes, M.1
Zuo, Y.2
Morrison, R.F.3
Silva, D.4
Park, B.H.5
Liu, J.6
Farmer, S.R.7
-
24
-
-
0034796784
-
Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: Evidence for selectivity in the downstream responses to PPAR gamma activation
-
Nugent, C., Prins, J. B., Whitehead, J. P., Savage, D., Wentworth, J. M., Chatterjee, V. K. and O'Rahilly, S. (2001). Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation. Mol. Endocrinol. 15, 1729-1738.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 1729-1738
-
-
Nugent, C.1
Prins, J.B.2
Whitehead, J.P.3
Savage, D.4
Wentworth, J.M.5
Chatterjee, V.K.6
O'Rahilly, S.7
-
25
-
-
2342613539
-
Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications
-
Nuttall, M. E. and Gimble, J. M. (2004). Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications. Curr. Opin. Pharmacol. 4, 290-294.
-
(2004)
Curr. Opin. Pharmacol.
, vol.4
, pp. 290-294
-
-
Nuttall, M.E.1
Gimble, J.M.2
-
26
-
-
0141483047
-
One strategy for cell and gene therapy: Harnessing the power of adult stem cells to repair tissues
-
Prockop, D. J., Gregory, C. A. and Spees, J. L. (2003). One strategy for cell and gene therapy: harnessing the power of adult stem cells to repair tissues. Proc. Natl. Acad. Sci. USA 100 Suppl. 1, 11917-11923.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.SUPPL. 1
, pp. 11917-11923
-
-
Prockop, D.J.1
Gregory, C.A.2
Spees, J.L.3
-
27
-
-
0034637103
-
Inhibition of adipogenesis by Wnt signaling
-
Ross, S. E., Hemati, N., Longo, K. A., Bennett, C. N., Lucas, P. C., Erickson, R. L. and MacDougald, O. A. (2000). Inhibition of adipogenesis by Wnt signaling. Science 289, 950-953.
-
(2000)
Science
, vol.289
, pp. 950-953
-
-
Ross, S.E.1
Hemati, N.2
Longo, K.A.3
Bennett, C.N.4
Lucas, P.C.5
Erickson, R.L.6
MacDougald, O.A.7
-
28
-
-
0036318980
-
Microarray analyses during adipogenesis: Understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism
-
Ross, S. E., Erickson, R. L., Gerin, L, DeRose, P. M., Bajnok, L., Longo, K. A., Misek, D. E., Kuick, R., Hanash, S. M., Atkins, K. B. et al. (2002). Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism. Mol. Cell. Biol. 22, 5989-5999.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5989-5999
-
-
Ross, S.E.1
Erickson, R.L.2
Gerin, L.3
DeRose, P.M.4
Bajnok, L.5
Longo, K.A.6
Misek, D.E.7
Kuick, R.8
Hanash, S.M.9
Atkins, K.B.10
-
29
-
-
0035954281
-
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6
-
Semenov, M. V., Tamai, K., Brott, B. K., Kuhl, M., Sokol, S. and He, X. (2001). Head inducer Dickkopf-l is a ligand for Wnt coreceptor LRP6. Curr. Biol. 11, 951-961.
-
(2001)
Curr. Biol.
, vol.11
, pp. 951-961
-
-
Semenov, M.V.1
Tamai, K.2
Brott, B.K.3
Kuhl, M.4
Sokol, S.5
He, X.6
-
30
-
-
0036309971
-
Regional differences in the response of human pre-adipocytes to PPARgamma and RXRalpha agonists
-
Sewter, C. P., Blows, F., Vidal-Puig, A. and O'Rahilly, S. (2002). Regional differences in the response of human pre-adipocytes to PPARgamma and RXRalpha agonists. Diabetes 51, 718-723.
-
(2002)
Diabetes
, vol.51
, pp. 718-723
-
-
Sewter, C.P.1
Blows, F.2
Vidal-Puig, A.3
O'Rahilly, S.4
-
31
-
-
0035902140
-
The Hedgehog and Wnt signalling pathways in cancer
-
Taipale, J. and Beachy, P. A. (2001). The Hedgehog and Wnt signalling pathways in cancer. Nature 411, 349-354.
-
(2001)
Nature
, vol.411
, pp. 349-354
-
-
Taipale, J.1
Beachy, P.A.2
-
32
-
-
0346363760
-
The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma
-
Tian, E., Zhan, F., Walker, R., Rasmussen, E., Ma, Y., Barlogie, B. and Shaughnessy, J. D., Jr (2003). The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N. Engl. J. Med. 349, 2483-2494.
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 2483-2494
-
-
Tian, E.1
Zhan, F.2
Walker, R.3
Rasmussen, E.4
Ma, Y.5
Barlogie, B.6
Shaughnessy Jr., J.D.7
-
33
-
-
0037373341
-
Six novel missense mutations in the LDL, receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density
-
Van Wesenbeeck, L., Cleiren, E., Gram, J., Beals, R. K., Benichou, O., Scopelliti, D., Key, L., Renton, T., Bartels, C., Gong, Y. et al. (2003). Six novel missense mutations in the LDL, receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density. Am. J. Hum. Genet, 72, 763-771.
-
(2003)
Am. J. Hum. Genet,
, vol.72
, pp. 763-771
-
-
Van Wesenbeeck, L.1
Cleiren, E.2
Gram, J.3
Beals, R.K.4
Benichou, O.5
Scopelliti, D.6
Key, L.7
Renton, T.8
Bartels, C.9
Gong, Y.10
-
34
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
Willert, K., Brown, J. D., Danenberg, E., Duncan, A. W., Weissman, I. L., Reya, T., Yates, J. R., 3rd and Nusse, R. (2003). Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423, 448-452.
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
Reya, T.6
Yates III, J.R.7
Nusse, R.8
-
35
-
-
0032406715
-
Mechanisms of Wnt signaling in development
-
Wodarz, A. and Nusse, R. (1998). Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 14, 59-88.
-
(1998)
Annu. Rev. Cell Dev. Biol.
, vol.14
, pp. 59-88
-
-
Wodarz, A.1
Nusse, R.2
-
36
-
-
0033543754
-
Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor 1
-
Xu, H., Sethi, J. K. and Hotamisligil, G. S. (1999). Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor 1. J. Biol. Chem. 274, 26287-26295.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26287-26295
-
-
Xu, H.1
Sethi, J.K.2
Hotamisligil, G.S.3
-
37
-
-
2442656675
-
The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd
-
Zhang, Y., Wang, Y., Li, X., Zhang, J., Mao, J., Li, Z., Zheng, J., Li, L., Harris, S. and Wu, D. (2004). The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd. Mol. Cell. Biol. 24, 4677-4684.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 4677-4684
-
-
Zhang, Y.1
Wang, Y.2
Li, X.3
Zhang, J.4
Mao, J.5
Li, Z.6
Zheng, J.7
Li, L.8
Harris, S.9
Wu, D.10
|