Variations in respiratory distress characterize the acute agonal period during heroin overdose death: Relevance to postmortem mRNA studies

Brain Research Bulletin

Volumn 70, Issue 3, 2006, Pages 251-259

  Horvath, Monika Cs ^a,b   Hurd, Yasmin L ^b   Rajs, Jovan ^b   Keller, Eva ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Brain pH; Dopamine; Opiate abuse; Opioid neuropeptide; Suicide

Indexed keywords

DIAMORPHINE; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; MESSENGER RNA; OPIATE; PROENKEPHALIN;

ADOLESCENT; ADULT; AGED; ALCOHOL INTOXICATION; ARTICLE; ASPHYXIA; AUTOPSY; BRAIN; BRAIN HYPOXIA; CAUSE OF DEATH; CONTROLLED STUDY; DEATH; DEMOGRAPHY; DRUG ABUSE; DRUG OVERDOSE; FEMALE; GENE EXPRESSION; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; INHALATION; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PH; PRIORITY JOURNAL; RESPIRATORY DISTRESS; RESUSCITATION; SUICIDE; VOMITING;

ADOLESCENT; ADULT; AGED; AUTOPSY; BRAIN CHEMISTRY; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ENKEPHALINS; ETHANOL; FEMALE; HEROIN; HUMANS; HYDROGEN-ION CONCENTRATION; IN SITU HYBRIDIZATION; MALE; MIDDLE AGED; OVERDOSE; PREVALENCE; PROTEIN PRECURSORS; RECEPTORS, DOPAMINE D2; RESPIRATORY DISTRESS SYNDROME, ADULT; RNA, MESSENGER; SUICIDE;

EID: 33745991210     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2006.05.010     Document Type: Article

References (40)

1. Barton A.J., Pearson R.C., Najlerahim A., and Harrison P.J. Pre- and postmortem influences on brain RNA. J. Neurochem. 61 (1993) 1-11
2. Bertram G.M., and Katzung. Basic & Clinical Pharmacology (2000), Appleton & Lange
3. Bowen D.M., Smith C.B., White P., and Davison A.N. Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies. Brain 99 (1976) 459-496
4. Bryant W.K., Gakea S., Tracy M., Markham Piper T., Tardiff K.J., and Vlahov D. Overdose deaths attributed to methadone and heroin in New York City, 1990-1998. Addiction 99 (2004) 846-854
5. Darke S., and Zador D. Fatal heroin 'overdose': a review. Addiction 91 (1996) 1765-1772
6. David D., Emma E.M., and Lew O. Forensic Pathology: Principles and Practice (2005), Academic Press (April 20)
7. Davidson P.J., Ochoa K.C., Hahn J.A., Evans J.L., and Moss A.R. Witnessing heroin-related overdoses: the experiences of young injectors in San Francisco. Addiction 97 (2002) 1511-1516
8. Dodd P.R., Hambley J.W., Cowburn R.F., and Hardy J.A. A comparison of methodologies for the study of functional transmitter neurochemistry in human brain. J. Neurochem. 50 (1988) 1333-1345
9. Fugelstad A., Ahlur J., Brandt L., Ceder G., Eksborg S., Rajs J., and Beck O. Use of morphine and 6-monoacetylmorphine in blood for the evaluation of possible risk factors for sudden death in 192 heroin users. Addiction 98 (2003) 463-470
10. Grandy D.K., Marchionni M.A., Makam H., Stofko R.E., Alfano M., Frothingham L., Fischer J.B., Burke-Howie K.J., Bunzow J.R., Server A.C., et al. Cloning of the cDNA and gene for a human D2 dopamine receptor. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 9762-9766
11. Hall W., Lynskey M., and Degenhardt L. Trends in opiate-related deaths in the United Kingdom and Australia, 1985-1995. Drug Alcohol Depend. 57 (2000) 247-254
12. Hardy J.A., Wester P., Winblad B., Gezelius C., Bring G., and Eriksson A. The patients dying after long terminal phase have acidotic brains; implications for biochemical measurements on autopsy tissue. J. Neural Transm. 61 (1985) 253-264
13. Harrison P.J., Health P.R., Eastwood S.L., Burnet P.W., McDonald B., and Pearson R.C. The relative importance of premortem acidosis and postmortem interval for human brain gene expression studies: selective mRNA vulnerability and comparison with their encoded proteins. Neurosci. Lett. 200 (1995) 151-154
14. Harrison P.J., Proctev A.W., Barton A.J., Lowe S.L., Najlerahim A., Bertolucci P.H., Bowen D.M., and Pearson R.C. Terminal coma affects messenger RNA detection in post mortem human temporal cortex. Mol. Brain Res. 9 (1991) 161-164
15. Henry J.A. Fatal opioid toxicity-a clinical perspective. Addiction 94 (1999) 974-975
16. Hickman M., Madden P., Henry J., Baker A., Wallace C., Wakefield J., Stimson G., and Elliott P. Trends in drug overdose deaths in England and Wales 1993-98: methadone does not kill more people than heroin. Addiction 98 (2003) 419-425
17. Hurd Y.L., Pristupa Z.B., Herman M.M., Niznik H.B., and Kleinman J.E. The dopamine transporter and dopamine D2 receptor mRNAs are differentially expressed in limbic- and motor-related subpopulations of human mesencephalic neurons. Neuroscience 63 (1994) 357-362
18. Hurd Y.L., and Sedvall GC S.M. D1 and D2 dopamine receptor mRNA expression in whole hemisphere sections of the human brain. J. Chem. Neuroanat. 22 (2001) 127-137
19. Hynd M.R., Scott L.J., and Dodd PR H.L. Biochemical and molecular studies using human autopsy brain tissue. J. Neurochem. 85 (2003) 543-562
20. Johnston N.L., Shore C.J., Torrey A.D., and Yolken RH E.F. Multivariate analysis of RNA levels from postmortem human brains as measured by three different methods of RT-PCR. Stanley neuropathology consortium. J. Neurosci. Methods 77 (1998) 83-92
21. Kingsbury A.E., Nisbet F.O., Cairns A.P., Bray N., Eve L., Lees D.J., and Marsden CD A.J. Tissue pH as an indicator of mRNA preservation in human post-mortem brain. Mol. Brain Res. 28 (1995) 311-318
22. Koob G.F. Neurobiology of addiction. Toward the development of new therapies. Ann. NY Acad. Sci. 909 (2000) 170-185
23. Larrinaga G., Meana G.J., Ruiz J.J.F., Callado L.F., and Irazusta J. Aminopeptidase activity in the postmortem brain of human heroin addicts. Neurochem. Int. 46 (2005) 213-219
24. Levine B., and Smialek JE G.D. The role of ethanol in heroin deaths. J. Forensic Sci. 40 (1995) 808-810
25. Li J.Z., Walsh V.M., Tomita D.M., Evans H., Choudary S.J., Lopez P.V., Avelar J.F., Shokoohi A., Chung V., Mesarwi T., Jones O., Watson E.G., Akil S.J., Bunney H., and Myers RM Jr. W.E. Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. Human Mol. Genet. 13 (2004) 609-616
26. Noda M., Teranishi Y., Takahashi H., Toyuosato M., Notake M., Nakanishi S., and Numa S. Isolation and structural organization of the human preproenkephalin gene. Nature 297 (1982) 431-434
27. Perry E.K., and Tomlinson BE P.R. The influence of agonal status on some neurochemical activities of postmortem human brain tissue. Neurosci. Lett. 29 (1982) 303-307
28. Polettini A., and Montagna M G.A. The role of alcohol abuse in the etiology of heroin-related deaths. Evidence for pharmacokinetic interactions between heroin and alcohol. J. Anal. Toxicol. 23 (1999) 570-576
29. Preece P.C.N. Quantifying mRNA in postmortem human brain: influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance. Mol. Brain Res. 118 (2003) 60-71
30. Preti A., and De Coppi M M.P. Deaths by unintentional illicit drug overdose in Italy. Drug Alcohol Depend. 66 (2002) 275-282
31. Ruttenber A.J., and Santinga K.H.P. The role of ethanol abuse in the etiology of heroin-related death. J. Forensic Sci. 35 (1990) 891-900
32. Schramm M., Tepest F.P., Schneider-Axmann R., Przkora T., Waha R., Pietsch A., Bonte T., and Bayer TA W. Stability of RNA transcripts in post-mortem psychiatric brains. J. Neural Transm. 106 (1999) 329-335
33. Sporer K. Acute heroin overdose. Ann. Intern. Med. 130 (1999) 584-590
34. Tang W.X., Mash F.W., and Hemby SE D.C. Molecular profiling of midbrain dopamine regions in cocaine overdose victims. J. Neurochem. 85 (2003) 911-924
35. Tintinalli J.E.K., Gabor D., Stapczynski, and Stephan J. Emergency Medicine: A Comprehensive Study Guide. sixth ed. (2003), McGraw-Hill Professional (October 14 2003 edn.)
36. Tomita H., Walsh V.M., Evans D.M., Choudary S.J., Li, Overman K.M., Atz M.E., Myers R.M., Jones E.G., Watson S.J., Akil H., and Bunney Jr. W.E. Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain. Biol. Psychiatry 55 (2004) 346-352
37. Warner-Smith M., and Day C D.S. Morbidity associated with non-fatal heroin overdose. Addiction 97 (2002) 963-967
38. Warner-Smith M., Lynskey D.S., and Hall W M. Heroin overdose: causes and consequences. Addiction 96 (2001) 1113-1125
39. Whitehouse P.J., and Kuhar MJ L.D. Effects of postmortem delay and temperature on neurotransmitter receptor binding in a rat model of the human autopsy process. J. Neurochem. 43 (1984) 553-559
40. Yates C.M., Tennant B.J., and Gordon A M.C. Enzyme activities in relation to pH and lactate in postmortem brain in Alzheimer-type and other dementias. J. Neurochem. 55 (1990) 1624-1630