Production by Clonostachys compactiuscula of a lovastatin esterase that converts lovastatin to monacolin J

Enzyme and Microbial Technology

Volumn 39, Issue 5, 2006, Pages 1051-1059

  Chen, Lin Cheng ^a   Lai, Yiu Kay ^a   Wu, Suh Chin ^a   Lin, Chih Chien ^a   Guo, Jia Hsin ^b  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL PINGTUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Clonostachys compactiuscula; Hypercholesterolemia; Lovastatin; Monacolin esterase; Response surface methodology

Indexed keywords

AMMONIUM COMPOUNDS; GLUCOSE; MATHEMATICAL MODELS; NUCLEAR MAGNETIC RESONANCE; PH EFFECTS; REGRESSION ANALYSIS; SIZE EXCLUSION CHROMATOGRAPHY; SUBSTRATES; SYNTHESIS (CHEMICAL);

CLONOSTACHYS COMPACTIUSCULA; HYPERCHOLESTEROLEMIA; LOVASTATIN; MONACOLIN ESTERASE; RESPONSE SURFACE METHODOLOGY;

ENZYMES;

ESTERASE; LOVASTATIN ESTERASE; MEVINOLIN; MONACOLIN J; UNCLASSIFIED DRUG;

ARTICLE; CLONOSTACHYS COMPACTIUSCULA; CONTROLLED STUDY; DRUG DESIGN; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ISOLATION; ENZYME PURIFICATION; FUNGAL STRAIN; FUNGUS GROWTH; GEL PERMEATION CHROMATOGRAPHY; ION EXCHANGE CHROMATOGRAPHY; MOLECULAR WEIGHT; MULTIPLE LINEAR REGRESSION ANALYSIS; MYCELIAL GROWTH; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PH MEASUREMENT; POLYACRYLAMIDE GEL ELECTROPHORESIS; RESPONSE SURFACE METHOD; STRUCTURE ANALYSIS;

CLONOSTACHYS COMPACTIUSCULA; FUNGI;

EID: 33745961745     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.enzmictec.2006.02.018     Document Type: Article

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