Proteomic analysis of rat liver phosphoproteins after treatment with protein kinase inhibitor H89 (N-(2-[p-bromocinnamylamino-]ethyl)-5- isoquinolinesulfonamide)

Journal of Pharmacology and Experimental Therapeutics

Volumn 318, Issue 2, 2006, Pages 589-595

  Davis, Myrtle A ^a   Hinerfeld, Douglas ^b   Joseph, Sajan ^a   Hui, Yu Hua ^a   Huang, Naijia H ^a   Leszyk, John ^b   Rutherford Bethard, Jennifer ^c   Tam, Sun W ^b  

^a ELI LILLY AND COMPANY   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOPLASMIC RETICULUM PROTEIN 44; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K; INITIATION FACTOR 4E; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHOPROTEIN; PROTEIN D FBPASE; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG; XY BODY ASSOCIATED PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG INHIBITION; ENZYME INHIBITION; ENZYME SUBSTRATE; IN VIVO STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PROTEOMICS; RAT; STATISTICAL ANALYSIS; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DATABASES, GENETIC; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME INHIBITORS; IMAGE PROCESSING, COMPUTER-ASSISTED; ISOQUINOLINES; LIVER; MALE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEOMICS; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SULFONAMIDES;

EID: 33745941919     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.100032     Document Type: Article

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