메뉴 건너뛰기




Volumn 44, Issue 1, 2006, Pages 174-185

Multiple polymorphic loci determine basal hepatic and splenic iron status in mice

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; COMPLEMENTARY DNA; HEME; IRON; TRANSFERRIN;

EID: 33745892389     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21233     Document Type: Article
Times cited : (18)

References (50)
  • 1
    • 2042546096 scopus 로고    scopus 로고
    • Balancing acts: Molecular control of mammalian iron metabolism
    • Hentze MW, Muckenthaler MU, Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell 2004;117:285-297.
    • (2004) Cell , vol.117 , pp. 285-297
    • Hentze, M.W.1    Muckenthaler, M.U.2    Andrews, N.C.3
  • 2
    • 0037101879 scopus 로고    scopus 로고
    • Ferritin, iron homeostasis, and oxidative damage
    • Arosio P, Levi S. Ferritin, iron homeostasis, and oxidative damage. Free Radic Biol Med 2002;33:457-463.
    • (2002) Free Radic Biol Med , vol.33 , pp. 457-463
    • Arosio, P.1    Levi, S.2
  • 3
    • 0033927849 scopus 로고    scopus 로고
    • Effects of HFE C282Y and H63D polymorphisms and polygenic background on iron stores in a large community sample of twins
    • Whitfield JB, Cullen LM, Jazwinska EC, Powell LW, Heath AC, Zhu G, et al. Effects of HFE C282Y and H63D polymorphisms and polygenic background on iron stores in a large community sample of twins. Am J Hum Genet 2000;66:1246-1258.
    • (2000) Am J Hum Genet , vol.66 , pp. 1246-1258
    • Whitfield, J.B.1    Cullen, L.M.2    Jazwinska, E.C.3    Powell, L.W.4    Heath, A.C.5    Zhu, G.6
  • 4
    • 0037132786 scopus 로고    scopus 로고
    • Penetrance of 845G→A (C282Y) HFE hereditary haemochromatosis mutation in the USA
    • Beutler E, Felitti VJ, Koziol JA, Ho NJ, Gelbart T. Penetrance of 845G→A (C282Y) HFE hereditary haemochromatosis mutation in the USA. Lancet 2002;359:211-218.
    • (2002) Lancet , vol.359 , pp. 211-218
    • Beutler, E.1    Felitti, V.J.2    Koziol, J.A.3    Ho, N.J.4    Gelbart, T.5
  • 5
    • 0036944167 scopus 로고    scopus 로고
    • Hereditary haemochromatosis: Only 1% of adult HFEC282Y homozygotes in South Wales have a clinical diagnosis of iron overload
    • McCune CA, Al-Jader LN, May A, Hayes SL, Jackson HA, Worwood M. Hereditary haemochromatosis: only 1% of adult HFEC282Y homozygotes in South Wales have a clinical diagnosis of iron overload. Hum Genet 2002;111:538-543.
    • (2002) Hum Genet , vol.111 , pp. 538-543
    • McCune, C.A.1    Al-Jader, L.N.2    May, A.3    Hayes, S.L.4    Jackson, H.A.5    Worwood, M.6
  • 7
    • 10744230824 scopus 로고    scopus 로고
    • Association between high serum ferritin levels and carotid atherosclerosis in the study of health in Pomerania (SHIP)
    • Wolff B, Volzke H, Ludemann J, Robinson D, Vogelgesang D, Staudt A, et al. Association between high serum ferritin levels and carotid atherosclerosis in the study of health in Pomerania (SHIP). Stroke 2004;35:453-457.
    • (2004) Stroke , vol.35 , pp. 453-457
    • Wolff, B.1    Volzke, H.2    Ludemann, J.3    Robinson, D.4    Vogelgesang, D.5    Staudt, A.6
  • 8
    • 18744424296 scopus 로고    scopus 로고
    • Relation between iron stores and non-insulin dependent diabetes in men: Case-control study
    • Salonen JT, Tuomainen TP, Nyyssonen K, Lakka HM, Punnonen K. Relation between iron stores and non-insulin dependent diabetes in men: case-control study. Br Med J 1998;317:727.
    • (1998) Br Med J , vol.317 , pp. 727
    • Salonen, J.T.1    Tuomainen, T.P.2    Nyyssonen, K.3    Lakka, H.M.4    Punnonen, K.5
  • 9
    • 0028216949 scopus 로고
    • Moderate elevation of body iron level and increased risk of cancer occurrence and death
    • Stevens RG, Graubard BI, Micozzi MS, Neriishi K, Blumberg BS. Moderate elevation of body iron level and increased risk of cancer occurrence and death. Int J Cancer 1994;56:364-369.
    • (1994) Int J Cancer , vol.56 , pp. 364-369
    • Stevens, R.G.1    Graubard, B.I.2    Micozzi, M.S.3    Neriishi, K.4    Blumberg, B.S.5
  • 10
    • 10744223646 scopus 로고    scopus 로고
    • Oxidative DNA damage (8-hydroxydeoxyguanosine) and body iron status: A study on 2507 healthy people
    • Nakano M, Kawanishi Y, Kamohara S, Uchida Y, Shiota M, Inatomi Y, et al. Oxidative DNA damage (8-hydroxydeoxyguanosine) and body iron status: a study on 2507 healthy people. Free Radic Biol Med 2003;35:826-832.
    • (2003) Free Radic Biol Med , vol.35 , pp. 826-832
    • Nakano, M.1    Kawanishi, Y.2    Kamohara, S.3    Uchida, Y.4    Shiota, M.5    Inatomi, Y.6
  • 11
    • 0034935074 scopus 로고    scopus 로고
    • Iron on the brain
    • Rouault TA. Iron on the brain. Nat Genet 2001;28:299-300.
    • (2001) Nat Genet , vol.28 , pp. 299-300
    • Rouault, T.A.1
  • 13
    • 0036728509 scopus 로고    scopus 로고
    • Iron and the anemia of chronic disease
    • Spivak JL. Iron and the anemia of chronic disease. Oncology (Williston Park) 2002;16:25-33.
    • (2002) Oncology (Williston Park) , vol.16 , pp. 25-33
    • Spivak, J.L.1
  • 14
    • 0034062537 scopus 로고    scopus 로고
    • Genes that modify the hemochromatosis phenotype in mice
    • Levy JE, Montross LK, Andrews NC. Genes that modify the hemochromatosis phenotype in mice. J Clin Invest 2000;105:1209-1216.
    • (2000) J Clin Invest , vol.105 , pp. 1209-1216
    • Levy, J.E.1    Montross, L.K.2    Andrews, N.C.3
  • 15
    • 0035942201 scopus 로고    scopus 로고
    • Naturally variant autosomal and sex-linked loci determine the severity of iron overload in beta 2-microglobulin-deficient mice
    • Sproule TJ, Jazwinska EC, Britton RS, Bacon BR, Fleming RE, Sly WS, et al. Naturally variant autosomal and sex-linked loci determine the severity of iron overload in beta 2-microglobulin-deficient mice. Proc Natl Acad Sci U S A 2001;98:5170-5174.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5170-5174
    • Sproule, T.J.1    Jazwinska, E.C.2    Britton, R.S.3    Bacon, B.R.4    Fleming, R.E.5    Sly, W.S.6
  • 16
    • 0035956992 scopus 로고    scopus 로고
    • Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis
    • Fleming RE, Holden CC, Tomatsu S, Waheed A, Brunt EM, Britton RS, et al. Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis. Proc Natl Acad Sci U S A 2001;98:2707-2711.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2707-2711
    • Fleming, R.E.1    Holden, C.C.2    Tomatsu, S.3    Waheed, A.4    Brunt, E.M.5    Britton, R.S.6
  • 19
    • 0036182842 scopus 로고    scopus 로고
    • Inactivation of the hemochromatosis gene differentially regulates duodenal expression of iron-related mRNAs between mouse strains
    • Dupic F, Fruchon S, Bensaid M, Borot N, Radosavljevic M, Loreal O, et al. Inactivation of the hemochromatosis gene differentially regulates duodenal expression of iron-related mRNAs between mouse strains. Gastroenterology 2002;122:745-751.
    • (2002) Gastroenterology , vol.122 , pp. 745-751
    • Dupic, F.1    Fruchon, S.2    Bensaid, M.3    Borot, N.4    Radosavljevic, M.5    Loreal, O.6
  • 20
    • 0029353515 scopus 로고
    • Dissociation between tissue iron concentrations and transferrin saturation among inbred mouse strains
    • Leboeuf RC, Tolson D, Heinecke JW. Dissociation between tissue iron concentrations and transferrin saturation among inbred mouse strains. J Lab Clin Med 1995;126:128-136.
    • (1995) J Lab Clin Med , vol.126 , pp. 128-136
    • Leboeuf, R.C.1    Tolson, D.2    Heinecke, J.W.3
  • 21
    • 0033036854 scopus 로고    scopus 로고
    • A genetic developmental model of iron deficiency: Biological aspects
    • Morse AC, Beard JL, Jones BC. A genetic developmental model of iron deficiency: biological aspects. Proc Soc Exp Biol Med 1999;220:147-152.
    • (1999) Proc Soc Exp Biol Med , vol.220 , pp. 147-152
    • Morse, A.C.1    Beard, J.L.2    Jones, B.C.3
  • 22
    • 0030893726 scopus 로고    scopus 로고
    • Protoporphyria induced by the orally active iron chelator 1,2-diethyl-3-hydroxypyridin-4-one in C57BL/10ScSn mice
    • Smith AG, Clothier B, Francis JE, Gibbs AH, De Matteis F, Hider RC. Protoporphyria induced by the orally active iron chelator 1,2-diethyl-3- hydroxypyridin-4-one in C57BL/10ScSn mice. Blood 1997;89:1045-1051.
    • (1997) Blood , vol.89 , pp. 1045-1051
    • Smith, A.G.1    Clothier, B.2    Francis, J.E.3    Gibbs, A.H.4    De Matteis, F.5    Hider, R.C.6
  • 23
    • 0033991142 scopus 로고    scopus 로고
    • Genetic variation of basal iron status, ferritin and iron regulatory protein in mice: Potential for modulation of oxidative stress
    • Clothier B, Robinson S, Akhtar RA, Francis JE, Peters TJ, Raja K, et al. Genetic variation of basal iron status, ferritin and iron regulatory protein in mice: potential for modulation of oxidative stress. Biochem Pharmacol 2000;59:115-122.
    • (2000) Biochem Pharmacol , vol.59 , pp. 115-122
    • Clothier, B.1    Robinson, S.2    Akhtar, R.A.3    Francis, J.E.4    Peters, T.J.5    Raja, K.6
  • 25
    • 0036838570 scopus 로고    scopus 로고
    • Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice
    • Dupic F, Fruchon S, Bensaid M, Loreal O, Brissot P, Borot N, et al. Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice. Gut 2002;51:648-653.
    • (2002) Gut , vol.51 , pp. 648-653
    • Dupic, F.1    Fruchon, S.2    Bensaid, M.3    Loreal, O.4    Brissot, P.5    Borot, N.6
  • 26
    • 33745882011 scopus 로고    scopus 로고
    • Mapping genes that influence iron metabolism using mouse chromosome substitution strains
    • Ajioka RS, LeBoef RC, Kushner JP. Mapping genes that influence iron metabolism using mouse chromosome substitution strains. Blood 2003;102:756a.
    • (2003) Blood , vol.102
    • Ajioka, R.S.1    LeBoef, R.C.2    Kushner, J.P.3
  • 28
    • 0041823366 scopus 로고    scopus 로고
    • SWR mice are highly susceptible to pulmonary infection with Mycobacterium tuberculosis
    • Turner OC, Keefe RG, Sugawara I, Yamada H, Orme IM. SWR mice are highly susceptible to pulmonary infection with Mycobacterium tuberculosis. Infect Immun 2003;71:5266-5272.
    • (2003) Infect Immun , vol.71 , pp. 5266-5272
    • Turner, O.C.1    Keefe, R.G.2    Sugawara, I.3    Yamada, H.4    Orme, I.M.5
  • 29
    • 20244387842 scopus 로고    scopus 로고
    • Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool
    • Davies R, Schuurman A, Barker CR, Clothier B, Chernova T, Higginson FM, et al. Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool. Am J Pathol 2005;166:1041-1053.
    • (2005) Am J Pathol , vol.166 , pp. 1041-1053
    • Davies, R.1    Schuurman, A.2    Barker, C.R.3    Clothier, B.4    Chernova, T.5    Higginson, F.M.6
  • 30
    • 0036179556 scopus 로고    scopus 로고
    • Non-ahr gene susceptibility loci for porphyria and liver injury induced by the interaction of 'dioxin' with iron overload in mice
    • Robinson SW, Clothier B, Akhtar RA, Yang AL, Latour I, Van Ijperen C, et al. Non-ahr gene susceptibility loci for porphyria and liver injury induced by the interaction of 'dioxin' with iron overload in mice. Mol Pharmacol 2002;61:674-681.
    • (2002) Mol Pharmacol , vol.61 , pp. 674-681
    • Robinson, S.W.1    Clothier, B.2    Akhtar, R.A.3    Yang, A.L.4    Latour, I.5    Van Ijperen, C.6
  • 32
    • 0028151261 scopus 로고
    • Empirical threshold values for quantitative trait mapping
    • Churchill GA, Doerge RW. Empirical threshold values for quantitative trait mapping. Genetics 1994;138:963-971.
    • (1994) Genetics , vol.138 , pp. 963-971
    • Churchill, G.A.1    Doerge, R.W.2
  • 33
    • 0037838823 scopus 로고    scopus 로고
    • Intrinsic hepatic phenotype associated with the Cyp1a2 gene as shown by cDNA expression microarray analysis of the knockout mouse
    • Smith AG, Davies R, Dalton TP, Miller ML, Judah D, Riley J, et al. Intrinsic hepatic phenotype associated with the Cyp1a2 gene as shown by cDNA expression microarray analysis of the knockout mouse. EHP Toxicogenomics 2003;111:45-51.
    • (2003) EHP Toxicogenomics , vol.111 , pp. 45-51
    • Smith, A.G.1    Davies, R.2    Dalton, T.P.3    Miller, M.L.4    Judah, D.5    Riley, J.6
  • 34
    • 8844224836 scopus 로고    scopus 로고
    • A statistical framework for the design of microarray experiments and effective detection of differential gene expression
    • Zhang SD, Gant TW. A statistical framework for the design of microarray experiments and effective detection of differential gene expression. Bioinformatics 2004;20:2821-2828.
    • (2004) Bioinformatics , vol.20 , pp. 2821-2828
    • Zhang, S.D.1    Gant, T.W.2
  • 35
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 2001;25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 36
    • 0033566343 scopus 로고    scopus 로고
    • Role of small differences in CYP1A2 in the development of uroporphyria produced by iron and 5-aminolevulinate in C57BL/6 and SWR strains of mice
    • Gorman N, Walton HS, Bement WJ, Honsinger CP, Szakacs JG, Sinclair JF, et al. Role of small differences in CYP1A2 in the development of uroporphyria produced by iron and 5-aminolevulinate in C57BL/6 and SWR strains of mice. Biochem Pharmacol 1999;58:375-382.
    • (1999) Biochem Pharmacol , vol.58 , pp. 375-382
    • Gorman, N.1    Walton, H.S.2    Bement, W.J.3    Honsinger, C.P.4    Szakacs, J.G.5    Sinclair, J.F.6
  • 37
    • 0037509928 scopus 로고    scopus 로고
    • Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis
    • Muckenthaler M, Roy CN, Custodio AO, Minana B, deGraaf J, Montross LK, et al. Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis. Nat Genet 2003;34:102-107.
    • (2003) Nat Genet , vol.34 , pp. 102-107
    • Muckenthaler, M.1    Roy, C.N.2    Custodio, A.O.3    Minana, B.4    Degraaf, J.5    Montross, L.K.6
  • 38
    • 2442681406 scopus 로고    scopus 로고
    • Different expression pattern of hepcidin genes in the liver and pancreas of C57BL/6N and DBA/2N mice
    • Krijt J, Cmejla R, Sykora V, Vokurka M, Vyoral D, Necas E. Different expression pattern of hepcidin genes in the liver and pancreas of C57BL/6N and DBA/2N mice. J Hepatol 2004;40:891-896.
    • (2004) J Hepatol , vol.40 , pp. 891-896
    • Krijt, J.1    Cmejla, R.2    Sykora, V.3    Vokurka, M.4    Vyoral, D.5    Necas, E.6
  • 42
    • 84940938275 scopus 로고    scopus 로고
    • Porphyria cutanea tarda and related disorders
    • Kadish KM, Smith KM, Guilard R, eds. Amsterdam, The Netherlands: Elsevier
    • Elder GH. Porphyria cutanea tarda and related disorders. In: Kadish KM, Smith KM, Guilard R, eds. The Porphyrin Handbook; vol 14, Medical Aspects of Porphyrins. Amsterdam, The Netherlands: Elsevier, 2003:67-92.
    • (2003) The Porphyrin Handbook; Vol 14, Medical Aspects of Porphyrins , vol.14 , pp. 67-92
    • Elder, G.H.1
  • 43
    • 0037174609 scopus 로고    scopus 로고
    • C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism
    • Courselaud B, Pigeon C, Inoue Y, Inoue J, Gonzalez FJ, Leroyer P, Gilot D, et al. C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism. J Biol Chem 2002;277:41163-41170.
    • (2002) J Biol Chem , vol.277 , pp. 41163-41170
    • Courselaud, B.1    Pigeon, C.2    Inoue, Y.3    Inoue, J.4    Gonzalez, F.J.5    Leroyer, P.6    Gilot, D.7
  • 44
    • 0345007046 scopus 로고
    • A revised nomenclature for the mouse transferrin locus
    • Cohen BL. A revised nomenclature for the mouse transferrin locus. Genet Res 1961;2:306-308.
    • (1961) Genet Res , vol.2 , pp. 306-308
    • Cohen, B.L.1
  • 48
    • 0029670047 scopus 로고    scopus 로고
    • Beta2 knockout mice develop parenchymal iron overload: A putative role for class I genes of the major histocompatibility complex in iron metabolism
    • Rothenberg BE, Voland JR. Beta2 knockout mice develop parenchymal iron overload: a putative role for class I genes of the major histocompatibility complex in iron metabolism. Proc Natl Acad Sci U S A 1996;93:1529-1534.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1529-1534
    • Rothenberg, B.E.1    Voland, J.R.2
  • 49
    • 0019272636 scopus 로고
    • Ly-m11: The H-3 region of mouse chromosome 2 controls a new surface alloantigen
    • Tada N, Kimura S, Hatzfeld A, Hammerling U. Ly-m11: the H-3 region of mouse chromosome 2 controls a new surface alloantigen. Immunogenetics 1980;11:441-449.
    • (1980) Immunogenetics , vol.11 , pp. 441-449
    • Tada, N.1    Kimura, S.2    Hatzfeld, A.3    Hammerling, U.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.