Regulation effect of nerve growth factor on Ras-MAPK signal transduction pathway in neurogenic inflammation of asthma

Journal of Central South University (Medical Sciences)

Volumn 31, Issue 3, 2006, Pages 319-325

  Tang, Yu Ling ^a   Hu, Cheng Ping ^a   Feng, Jun Tao ^a   Zhu, Jin Qi ^a   Lin, Min Juan ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Asthma; Nerve growth factor; Ras MAPK signal transduction pathway

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CELL EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR ANTIBODY; OVALBUMIN; PROTEIN C FOS; PROTEIN KINASE C; RAS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; CONTROLLED STUDY; DRUG INHIBITION; IMMUNOHISTOCHEMISTRY; NEUROGENIC INFLAMMATION; NONHUMAN; PROTEIN EXPRESSION; RAT; SPINAL GANGLION; WESTERN BLOTTING;

ANIMALS; ASTHMA; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE GROWTH FACTOR; NEUROGENIC INFLAMMATION; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 33745887222     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Hu C, Wedde-Beer K, Auais A, et al. Nerve growth factor and nerve growth factor receptors in respiratory syncytial virus-infected lungs[J]. Am J Physiol Lung Cell Mol Physiol, 2002, 283(2):494-502.
2. Kolch W. The regulation of the Ras/ Raf/ MEK/ ERK pathway by protein interactions[J]. Biochem J, 2000, 351 (2):289-305.
3. Krymskaya VP, Orsini MJ, Eszterhas AJ, et al. Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle [J]. Am J Respir Cell Mol Biol, 2000, 23(4):546-554.
4. Irusen E, Matthews JG, Takahashi A, et al. p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma[J]. J Allergy Clin Immunol, 2002, 109(4):649-657.
5. Miura K, Schroeder JT, Hubbard WC, et al. Extracellular signal-regulated kinases regulate leukotriene C4 generation, but not histamine release or IL-4 production from human basophils [J]. J Immunol, 1999, 162(7):4198-4206.
6. De Vries A, Engels F, Henricks PA, et al. Antibodies directed against nerve growth factor inhibit the acute bronchoconstriction due to allergen challenge in guinea-pigs[J]. Clin Exp Allergy, 2002, 32(2):325-328.
7. Hunter D, Undem B. Nerve growth factor-induced phenotypic switch in guinea pig airway sensory neurons[J]. Am J Respir Crit Care Med, 2000, 161(6):1985-1990.
8. Richard D, Naline E, Drapeau G. Origin and colocalization of CGRP- and SP- reactive nerves in cat airway epithelium[J]. J Appl Physiol, 1990, 68(2):770-778.
9. Lindsay RM, Harmar AJ. Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons[J]. Nature, 1989, 337(6205):362-364.
10. Braun A, Appel E, Baruch R, et al. Role of nerve growth factor in a mouse model allergic airway inflammation and asthma[J]. Eur J Immunol, 1998, 28(10):3240-3251.
11. Averill S, Delcroix JD, Michael GJ, et al. Nerve growth factor modulates the activation status and fast axonal transport of erk1/2 in adult nociceptive neurons[J]. Mol Cell Neurosci, 2001, 18(2):183-196.