A G316A mutation of manganese lipoxygenase augments hydroperoxide isomerase activity: Mechanism of biosynthesis of epoxyalcohols

Journal of Biological Chemistry

Volumn 281, Issue 26, 2006, Pages 17612-17623

  Cristea, Mirela ^a   Oliw, Ernst H ^a,b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; BIOCHEMISTRY; BIOSYNTHESIS; CATALYSIS; FATTY ACIDS; ISOMERS; MUTAGENESIS; OXYGENATORS; STEREOCHEMISTRY;

EPOXYALCOHOLS; HYDROPEROXIDES; LIPOXYGENASE AUGMENTS; OXYGENATION;

MANGANESE COMPOUNDS;

(13R) HYDROPEROXYLINOLENIC ACID; 13 KETOLINOLENIC ACID; ALCOHOL DERIVATIVE; EPOXIDE; EPOXYALCOHOL DERIVATIVE; FATTY ACID; HYDROPEROXIDE; ISOMERASE; LINOLENIC ACID; LIPOXYGENASE; MANGANESE LIPOXYGENASE; OXYGEN; THREO 11 HYDROXY (12R,13R) EPOXY (9Z,15Z) OCTADECADIENOIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CATALYSIS; ENZYME ACTIVITY; MUTATIONAL ANALYSIS; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS;

ALCOHOLS; ALPHA-LINOLENIC ACID; AMINO ACID SEQUENCE; ANAEROBIOSIS; ANIMALS; CONSERVED SEQUENCE; ENZYME ACTIVATION; EPOXY COMPOUNDS; FATTY ACIDS, OMEGA-3; HEMIN; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; LIPID PEROXIDES; LIPOXYGENASE; MICE; MUTAGENESIS, SITE-DIRECTED; OXYGEN; PICHIA; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

PICHIA PASTORIS;

EID: 33745873656     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M510311200     Document Type: Article

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