Synthesis and biological evaluation of a fluorine-18-labeled nonsteroidal androgen receptor antagonist, N-(3-[18F]fluoro-4-nitronaphthyl)-cis-5-norbornene-endo-2,3-dicarboxylic imide

Nuclear Medicine and Biology

Volumn 33, Issue 5, 2006, Pages 615-624

  Parent, Ephraim E ^a   Dence, Carmen S ^b   Sharp, Terry L ^b   Welch, Michael J ^b   Katzenellenbogen, John A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Androgen receptor; Fluorine 18; Nonsteroidal androgen

Indexed keywords

AMMONIA; ANDROGEN RECEPTOR ANTAGONIST; BUFFER; DIETHYLSTILBESTROL; FLUORINE; N (3 FLUORO 4 NITRONAPHTHYL) 5 NORBORNENE ENDO 2,3 DICARBOXYLIC IMIDE F18; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; RADIOLIGAND; RECEPTOR BLOCKING AGENT; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; DEFLUORINATION; DISPLACEMENT BEHAVIOR; DRUG BINDING; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; IMAGING; IN VITRO STUDY; ISOTOPE LABELING; MALE; METABOLISM; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT; RECEPTOR AFFINITY; TARGET ORGAN; TISSUE DISTRIBUTION;

ANIMALS; DRUG EVALUATION, PRECLINICAL; ISOTOPE LABELING; MALE; METABOLIC CLEARANCE RATE; NORBORNANES; ORGAN SPECIFICITY; POSITRON-EMISSION TOMOGRAPHY; PROSTATE; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN; SUCCINIMIDES; TISSUE DISTRIBUTION;

EID: 33745872521     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2006.04.003     Document Type: Article

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