Poxvirus mRNA cap methyltransferase: Bypass of the requirement for the stimulatory subunit by mutations in the catalytic subunit and evidence for intersubunit allostery

Journal of Biological Chemistry

Volumn 281, Issue 28, 2006, Pages 18953-18960

  Schwer, Beate ^b   Hausmann, Stéphane ^a   Schneider, Susanne ^b   Shuman, Stewart ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; GENES; MOLECULAR BIOLOGY; MUTAGENESIS; PROTEINS; RNA;

MUTATIONS; POXVIRUS PROTEINS; POXVIRUS SUBUNITS; SACCHAROMYCES;

ENZYME KINETICS;

ASPARAGINE; CYSTEINE; GUANINE; HISTIDINE; ISOLEUCINE; MESSENGER RNA; METHYLTRANSFERASE; PROTEIN SUBUNIT; PROTEIN VD1; PROTEIN VD12; SERINE; TYROSINE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ALLOSTERISM; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; GENETIC SCREENING; MISSENSE MUTATION; NONHUMAN; POXVIRUS; PRIORITY JOURNAL;

ALLELES; ALLOSTERIC SITE; CATALYTIC DOMAIN; DIMERIZATION; GUANINE; KINETICS; METHYLTRANSFERASES; MUTATION; POXVIRIDAE; PROTEIN BINDING; PROTEIN ENGINEERING; RNA; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; VACCINIA VIRUS;

POXVIRIDAE; SACCHAROMYCES CEREVISIAE; VACCINIA VIRUS;

EID: 33745868309     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M602867200     Document Type: Article

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