Abundance of the largest subunit of RNA polymerase II in the nucleus is regulated by nucleo-cytoplasmic shuttling

Experimental Cell Research

Volumn 312, Issue 13, 2006, Pages 2557-2567

  Custódio, Noélia ^a   Antoniou, Michael ^b   Carmo Fonseca, Maria ^a  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b GUY S HOSPITAL   (United Kingdom)

Author keywords

CRM1; Nuclear export; Nucleo cytoplasmic shuttling; RNA polymerase II

Indexed keywords

ALPHA AMANITIN; EXPORTIN 1; PHOSPHOSERINE; RNA POLYMERASE II;

ANIMAL CELL; ARTICLE; CELL LINE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; ENZYME SUBUNIT; MOUSE; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

EUKARYOTA; MURINAE;

EID: 33745835437     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2006.04.018     Document Type: Article

References (49)

1. Shilatifard A., Conaway R.C., and Conaway J.W. The RNA polymerase II elongation complex. Annu. Rev. Biochem. 72 (2003) 693-715
2. Corden J.L., Cadena D.L., Ahearn Jr. J.M., and Dahmus M.E. A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II. Proc. Natl. Acad. Sci. U. S. A. 82 (1985) 7934-7938
3. Corden J.L. Tails of RNA polymerase II. Trends Biochem. Sci. 15 (1990) 383-387
4. West M.L., and Corden J.L. Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations. Genetics 140 (1995) 1223-1233
5. Bensaude O., Bonnet F., Casse C., Dubois M.F., Nguyen V.T., and Palancade B. Regulated phosphorylation of the RNA polymerase II C-terminal domain (CTD). Biochem. Cell. Biol. 77 (1999) 249-255
6. Kim W.Y., and Dahmus M.E. Immunochemical analysis of mammalian RNA polymerase II subspecies. Stability and relative in vivo concentration. J. Biol. Chem. 261 (1986) 14219-14225
7. Lu H., Flores O., Weinmann R., and Reinberg D. The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 10004-10008
8. Chesnut J.D., Stephens J.H., and Dahmus M.E. The interaction of RNA polymerase II with the adenovirus-2 major late promoter is precluded by phosphorylation of the C-terminal domain of subunit IIa. J. Biol. Chem. 267 (1992) 10500-10506
9. Komarnitsky P., Cho E.J., and Buratowski S. Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev. 14 (2000) 2452-2460
10. Cho H., Kim T.K., Mancebo H., Lane W.S., Flores O., and Reinberg D. A protein phosphatase functions to recycle RNA polymerase II. Genes Dev. 13 (1999) 1540-1552
11. Kobor M.S., Archambault J., Lester W., Holstege F.C., Gileadi O., Jansma D.B., Jennings E.G., Kouyoumdjian F., Davidson A.R., Young R.A., and Greenblatt J. An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae. Mol. Cell 4 (1999) 55-62
12. Antoniou A. Induction of erythroid-specific expression in murine erythroleukemia (MEL) cells. In: Murray E.J. (Ed). Methods in Molecular Biology: Gene transfer and Expression Protocols vol. 7 (1991), The Human Press Inc., Clinfton, NJ 421-434
13. Gerber H.P., Hagmann M., Seipel K., Georgiev O., West M.A., Litingtung Y., Schaffner W., and Corden J.L. RNA polymerase II C-terminal domain required for enhancer-driven transcription. Nature 374 (1995) 660-662
14. Collis P., Antoniou M., and Grosveld F. Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expression. EMBO J. 9 (1990) 233-240
15. Antoniou M., Geraghty F., Hurst J., and Grosveld F. Efficient 3′-end formation of human β-globin mRNA in vivo requires sequences within the last intron but occurs independently of the splicing reaction. Nucleic Acids Res. 26 (1998) 721-729
16. de Boer E., Antoniou M., Mignotte V., Wall L., and Grosveld F. The human beta-globin promoter; nuclear protein factors and erythroid specific induction of transcription. EMBO J. 7 (1988) 4203-4212
17. Kramer A., Haars R., Kabisch R., Will H., Bautz F.A., and Bautz E.K. Monoclonal antibody directed against RNA polymerase II of Drosophila melanogaster. Mol. Gen. Genet. 180 (1980) 193-199
18. Thompson N.E., Steinberg T.H., Aronson D.B., and Burgess R.R. Inhibition of in vivo and in vitro transcription by monoclonal antibodies prepared against wheat germ RNA polymerase II that react with the heptapeptide repeat of eukaryotic RNA polymerase II. J. Biol. Chem. 264 (1989) 11511-11520
19. Warren S.L., Landolfi A.S., Curtis C., and Morrow J.S. Cytostellin: a novel, highly conserved protein that undergoes continuous redistribution during the cell cycle. J. Cell Sci. 103 Pt 2 (1992) 381-388
20. Bregman D.B., Du L., vanderZee S., and Warren S.L. Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains. J. Cell Biol. 129 (1995) 287-298
21. Thibodeau A., and Vincent M. Monoclonal antibody CC-3 recognizes phosphoproteins in interphase and mitotic cells. Exp. Cell Res. 195 (1991) 145-153
22. Vincent M., Lauriault P., Dubois M.F., Lavoie S., Bensaude O., and Chabot B. The nuclear matrix protein p255 is a highly phosphorylated form of RNA polymerase II largest subunit which associates with spliceosomes. Nucleic Acids Res. 24 (1996) 4649-4652
23. Lerner E.A., Lerner M.R., Janeway Jr. C.A., and Steitz J.A. Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease. Proc. Natl. Acad. Sci. U. S. A. 78 (1981) 2737-2741
24. Choi Y.D., and Dreyfuss G. Monoclonal antibody characterization of the C proteins of heterogeneous nuclear ribonucleoprotein complexes in vertebrate cells. J. Cell Biol. 99 (1984) 204-1997
25. Guillot P.V., Xie S.Q., Hollinshead M., and Pombo A. Fixation-induced redistribution of hyperphosphorylated RNA polymerase II in the nucleus of human cells. Exp. Cell Res. 295 (2004) 460-468
26. Pombo A., Cuello P., Schul W., Yoon J.B., Roeder R.G., Cook P.R., and Murphy S. Regional and temporal specialization in the nucleus: a transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle. EMBO J. 17 (1998) 1768-1778
27. Fey E.G., Krochmalnic G., and Penman S. The nonchromatin substructures of the nucleus: the ribonucleoprotein (RNP)-containing and RNP-depleted matrices analyzed by sequential fractionation and resinless section electron microscopy. J. Cell Biol. 102 (1986) 1654-1665
28. Bushnell D.A., Cramer P., and Kornberg R.D. Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 1218-1222
29. Bartolomei M.S., and Corden J.L. Localization of an alpha-amanitin resistance mutation in the gene encoding the largest subunit of mouse RNA polymerase II. Mol. Cell. Biol. 7 (1987) 586-594
30. BlomvanAssendelft G., Hanscombe O., Grosveld F., and Greaves D.R. The beta-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner. Cell 56 (1989) 969-977
31. Antoniou M., and Grosveld F. beta-globin dominant control region interacts differently with distal and proximal promoter elements. Genes Dev. 4 (1990) 1007-1013
32. Nguyen V.T., Giannoni F., Dubois M.F., Seo S.J., Vigneron M., Kedinger C., and Bensaude O. In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin. Nucleic Acids Res. 24 (1996) 2924-2929
33. Lamond A.I., and Spector D.L. Nuclear speckles: a model for nuclear organelles. Nat. Rev., Mol. Cell Biol. 4 (2003) 605-612
34. Antoniou M., Carmo-Fonseca M., Ferreira J., and Lamond A.I. Nuclear organization of splicing snRNPs during differentiation of murine erythroleukemia cells in vitro. J. Cell Biol. 123 (1993) 1055-1068
35. Palancade B., and Bensaude O. Investigating RNA polymerase II carboxyl-terminal domain (CTD) phosphorylation. Eur. J. Biochem. 270 (2003) 3859-3870
36. Patturajan M., Schulte R.J., Sefton B.M., Berezney R., Vincent M., Bensaude O., Warren S.L., and Corden J.L. Growth-related changes in phosphorylation of yeast RNA polymerase II. J. Biol. Chem. 273 (1998) 4689-4694
37. Jones J.C., Phatnani H.P., Haystead T.A., MacDonald J.A., Alam S.M., and Greenleaf A.L. C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats. J. Biol. Chem. 279 (2004) 24957-24964
38. Cho E.J., Takagi T., Moore C.R., and Buratowski S. mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev. 11 (1997) 3319-3326
39. Valay J.G., Simon M., Dubois M.F., Bensaude O., Facca C., and Faye G. The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD. J. Mol. Biol. 249 (1995) 535-544
40. Bonnet F., Vigneron M., Bensaude O., and Dubois M.F. Transcription-independent phosphorylation of the RNA polymerase II C-terminal domain (CTD) involves ERK kinases (MEK1/2). Nucleic Acids Res. 27 (1999) 4399-4404
41. Fornerod M., Ohno M., Yoshida M., and Mattaj I.W. CRM1 is an export receptor for leucine-rich nuclear export signals. Cell 90 (1997) 1051-1060
42. Kudo N., Matsumori N., Taoka H., Fujiwara D., Schreiner E.P., Wolff B., Yoshida M., and Horinouchi S. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 9112-9117
43. Pinol-Roma S., and Dreyfuss G. Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm. Nature 355 (1992) 730-732
44. Zeng C., Kim E., Warren S.L., and Berget S.M. Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity. EMBO J. 16 (1997) 1401-1412
45. Grande M.A., van der Kraan I., de Jong L., and van Driel R. Nuclear distribution of transcription factors in relation to sites of transcription and RNA polymerase II. J. Cell Sci. 110 Pt 15 (1997) 1781-1791
46. Bregman D.B., Du L., Li Y., Ribisi S., and Warren S.L. Cytostellin distributes to nuclear regions enriched with splicing factors. J. Cell Sci. 107 Pt 3 (1994) 387-396
47. Sugaya K., Vigneron M., and Cook P.R. Mammalian cell lines expressing functional RNA polymerase II tagged with the green fluorescent protein. J. Cell Sci. 113 Pt 15 (2000) 2679-2683
48. Lavoie S.B., Albert A.L., Handa H., Vincent M., and Bensaude O. The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9. J. Mol. Biol. 312 (2001) 675-685
49. Albert A.L., Lavoie S.B., and Vincent M. Multisite phosphorylation of Pin1-associated mitotic phosphoproteins revealed by monoclonal antibodies MPM-2 and CC-3. BMC Cell Biol. 5 (2004) 22