The complement regulator C4b-binding protein (C4BP) interacts with both the C4c and C4dg subfragments of the parent C4b ligand: Evidence for synergy in C4BP subsite binding

Biochemistry

Volumn 45, Issue 27, 2006, Pages 8378-8392

  Leung, Elisa ^a   Blom, Anna M ^b   Clemenza, Liliana ^a,c   Isenman, David E ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b LUND UNIVERSITY   (Sweden)

^c PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; CONFORMATIONS; INTERFACES (MATERIALS); MOLECULAR STRUCTURE; SURFACE PLASMON RESONANCE;

C4B-BINDING PROTEIN (C4BP); COMPLEMENT CONTROL PROTEIN (CCP); SERUM PROTEIN;

PROTEINS;

BINDING PROTEIN; COMPLEMENT; COMPLEMENT COMPONENT C4B; COMPLEMENT COMPONENT C4C; COMPLEMENT COMPONENT C4D; COMPLEMENT CONTROL PROTEIN 1; COMPLEMENT CONTROL PROTEIN 2; PLASMA PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEMENT CLASSICAL PATHWAY; COMPLEMENT LECTIN PATHWAY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SURFACE PLASMON RESONANCE;

AMINO ACID SEQUENCE; BINDING SITES; COMPLEMENT C4; COMPLEMENT C4B-BINDING PROTEIN; HEPARIN; HUMANS; LIGANDS; MUTATION; OSMOLAR CONCENTRATION; PEPTIDE FRAGMENTS; SURFACE PLASMON RESONANCE;

EID: 33745826305     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0603827     Document Type: Article

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