Design and synthesis of novel 2-amino-5-hydroxyindole derivatives that inhibit human 5-lipoxygenase

Journal of Medicinal Chemistry

Volumn 49, Issue 14, 2006, Pages 4327-4332

  Landwehr, Jens ^a   George, Sven ^b   Karg, Eva Maria ^a   Poeckel, Daniel ^c   Steinhilber, Dieter ^b   Troschuetz, Reinhard ^a   Werz, Oliver ^c  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 HYDROXYINDOLE DERIVATIVE; 5 HYDROXYINDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL PERMEABILITY; CELL FREE SYSTEM; DERIVATIZATION; DRUG ACTIVITY; DRUG DESIGN; DRUG EFFECT; DRUG ISOLATION; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; NEUTROPHIL; OXIDATION REDUCTION REACTION;

AMINES; ARACHIDONATE 5-LIPOXYGENASE; ESCHERICHIA COLI; HUMANS; INDOLES; LEUKOCYTES; RECOMBINANT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33745820850     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050801i     Document Type: Article

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