A test system for leukotriene synthesis inhibitors based on the in-vitro differentiation of the human leukemic cell lines HL-60 and Mono Mac 6

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 356, Issue 4, 1997, Pages 441-445

  Werz, Oliver ^a   Schneider, Nicole ^b   Brungs, Martina ^a   Sailer, Eckart Roderich ^b   Safayhi, Hasan ^b   Ammon, Hermann P T ^b   Steinhilber, Dieter ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

5 Lipoxygenase; HL 60; Inhibitors; Leukotriene; Mono Mac 6

Indexed keywords

1 ETHYL 6 [[3 FLUORO 5 (3,4,5,6 TETRAHYDRO 4 METHOXY 2H PYRAN 4 YL)]PHENOXYMETHYL] 2 QUINOLONE; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; CALCITRIOL; LIPOXYGENASE INHIBITOR; N [3 (3 PHENOXYPHENYL)ALLYL]ACETOHYDROXAMIC ACID; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKOCYTE; PROTEIN EXPRESSION;

ARACHIDONATE 5-LIPOXYGENASE; BENZENEACETAMIDES; CELL DIFFERENTIATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INDUCTION; HL-60 CELLS; HUMANS; HYDROXAMIC ACIDS; INDOLES; LEUKEMIA, MONOCYTIC, CHRONIC; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENES; PYRANS; QUINOLONES; TRITERPENES; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0030875291     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005074     Document Type: Article

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