Inhibition of PGI2 signaling by miconazole in vascular smooth muscle cells

Prostaglandins and Other Lipid Mediators

Volumn 80, Issue 1-2, 2006, Pages 28-34

  Zhou, Wei ^a   Lu, Tong ^a   Spector, Arthur A ^b   Lee, Hon Chi ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Arachidonic acid; Carbacyclin; Cytochrome P450; Miconazole; PGI2; Smooth muscle cells

Indexed keywords

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; ANTIFUNGAL AGENT; ARACHIDONIC ACID; CARBACYCLIN; CYCLIC AMP; CYTOCHROME P450 INHIBITOR; ILOPROST; MICONAZOLE; PHOSPHODIESTERASE INHIBITOR; POTASSIUM CHANNEL; PROADIFEN; PROSTACYCLIN; DRUG DERIVATIVE; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTERY DILATATION; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CORONARY ARTERY; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MALE; MESENTERIC ARTERY; METABOLITE; NONHUMAN; POTASSIUM CURRENT; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; VASODILATATION; ANIMAL; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; PHYSIOLOGY; SPRAGUE DAWLEY RAT; ZUCKER RAT;

4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE; ANIMALS; CYCLIC AMP; EPOPROSTENOL; HUMANS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MALE; MICONAZOLE; MUSCLE, SMOOTH, VASCULAR; PROADIFEN; RATS; RATS, SPRAGUE-DAWLEY; RATS, ZUCKER; SIGNAL TRANSDUCTION; VASODILATION;

EID: 33745806593     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2006.03.005     Document Type: Article

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