Transmembrane signaling through phospholipase C-β in the developing human prefrontal cortex

Journal of Neuroscience Research

Volumn 84, Issue 1, 2006, Pages 13-26

  De Azúa, Iñigo Ruiz ^a   Del Olmo, Elena ^b   Pazos, Angel ^b   Sallés, Joan ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

Cerebral cortex; G q 11 sub units; Muscarinic receptor subtypes; Ontogenic development; Phospholipase C 1 4 isoforms

Indexed keywords

CALCIUM ION; CARBACHOL; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INOSITOL PHOSPHATE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M5 RECEPTOR; MUSCARINIC RECEPTOR; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPASE C BETA1; PHOSPHOLIPASE C BETA2; PHOSPHOLIPASE C BETA3; PHOSPHOLIPASE C BETA4;

ADOLESCENT; ADULT; ARTICLE; BRAIN DEVELOPMENT; BRAIN MEMBRANE; CHILD; DEVELOPMENTAL STAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; FEMALE; FETUS; HUMAN; HUMAN TISSUE; MALE; NEWBORN; POSTNATAL DEVELOPMENT; PREFRONTAL CORTEX; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTINS; ADOLESCENT; ADULT; CELL MEMBRANE; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; MALE; PHOSPHOLIPASE C; PREFRONTAL CORTEX; PROTEIN BINDING; QUINUCLIDINYL BENZILATE; RADIOLIGAND ASSAY; RECEPTORS, MUSCARINIC; SIGNAL TRANSDUCTION; TRITIUM;

EID: 33745803822     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20858     Document Type: Article

References (59)

1. Aguilar JS, Lunt GG. 1985. Muscarinic receptor sites in human fetal brain. Neurochem Int 7:509-514.
2. Balduini W, Murphy SD, Costa LG. 1987. Developmental changes in muscarinic receptor-stimulated phosphoinositide metabolism in rat brain. J Pharmacol Exp Ther 241:421-427.
3. Bar-Peled O, Israeli M, Ben-Hur H, Hoskins I, Groner Y, Biegon A. 1991. Developmental pattern of muscarinic receptors in normal and Down's syndrome fetal brain: an autoradiographic study. Neurosci Lett 133:154-158.
4. Buckley NJ, Bonner TI, Buckley CM, Brann MR. 1989. Antagonist binding properties of five cloned human muscarinic receptor subtypes. Mol Pharmacol 35:469-476.
5. 2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain. J Biol Chem 269:12190-12195.
6. Candura SM, Tonini M, Baiardi P, Manzo L, Costa LG. 1995. Heterogeneity of cholinergic muscarinic receptors coupled to phosphoinositide metabolism in immature rat brain. Brain Res Dev Brain Res 86:134-142.
7. q/11 by RGS domain in the G protein-coupled kinase, GRK2. J Biol Chem 274:34483-34492.
8. Caulfield MP. 1993. Muscarinic receptors-characterization, coupling and function. Pharmacol Ther 58:319-379.
9. Claro E, Wallace MA, Lee HM, Fain JN. 1989. Carbachol in the presence of guanine 5′-O-(3-thiotriphosphate) stimulates the breakdown of exogenous phosphatidylinositol 4,5-biphosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol by rat brain membranes. J Biol Chem 264:18288-18295.
10. Cortés R, Probst A, Palacios JM. 1987. Quantitative light microscopic autoradiographic localization of cholinergic muscarinic receptors in the human brain: forebrain. Neuroscience 20:65-107.
11. Crews FT, Kurian P, Freund G. 1994. Cholinergic and serotonergic stimulation of phosphoinositide hydrolysis is decreased in Alzheimer's disease. Life Sci 55:1993-2002.
12. Debburman SK, Kunapuli P, Benovic JL, Hosey M. 1995. Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases. Mol Pharmacol 47:224-233.
13. Dobbing J, Sands J. 1979. Comparative aspects of the brain growth spurt. Early Hum Dev 3:79-83.
14. Dorje F, Wess J, Lambrecht G, Tacke R, Mutschler E, Brann MR. 1991. Antagonist binding profiles of five cloned muscarinic receptor subtypes. J Pharmacol Exp Ther 256:727-733.
15. Eglen RM, Nahorski SR. 2000. The muscarinic M5 receptor: a silent or emerging subtype? Br J Pharmacol 130:13-21.
16. Egozi Y, Sokolovsky M, Schefter E, Blatt Y, Zakut H, Matzkel A, Soreq H. 1986. Divergent regulation of muscarinic binding sites and acetylcholinesterase in discrete regions of the developing human fetal brain. Cell Mol Neurobiol 6:55-70.
17. Felder CC. 1995. Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J 9:619-625.
18. Fleming WW, Westfall DP, De La Lande IS, Jellett LB. 1972. Long-normal distribution of equieffective doses of norepinephrine and acetylcholine in several tissues. J Pharmacol Exp Ther 181:339-345.
19. Florez J, Del Arco C, Gonzalez A, Pascual J, Pazos A. 1990. Autoradiographic studies of neurotransmitter receptors in the brain of newborn infants with Down's syndrome. Am J Med Genet 7:301-305.
20. Flynn DD, Ferrari-DiLeo G, Mash DC, Levey AI. 1995. Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease. J Neurochem 64:1888-1891.
21. Flynn DD, Reever CM, Ferrari-DiLeo G. 1997. Pharmacological strategies to selectively label and localize receptor subtypes. Drug Dev Res 40:104-116.
22. Forray C, El-Fakahany EE. 1990. On the involvement of multiple muscarinic receptor subtypes in the activation of phosphoinositide metabolism in rat cerebral cortex. Mol Pharmacol 37:893-902.
23. Garro MA, López De Jesús M, Ruiz de Azúa I, Callado LF, Meana JJ, Sallés J. 2001. Regulation of phospholipase Cβ activity by muscarinic acetykholine and 5-HT2 receptors in crude and synaptosomal membranes from human cerebral cortex. Neuropharmacology 40:686-695.
24. Garro MA, López de Jesús M, Ruiz de Azúa I, Callado LF, Meana JJ, Sallés J. 2004. Differential post-mortem delay effect on agonist-mediated phospholipase Cβ activity in human cortical crude and synaptosomal membranes. Neurochem Res 29:1453-1457.
25. Greenwood AF, Powers RE, Jope RS. 1995. Phosphoinositide hydrolysis, Gaq, phospholipase C, and protein kinase C in post mortem human brain: effects of post mortem interval, subject age and Alzheimer's disease. Neuroscience 69:125-138.
26. Gremo F, Palomba M, Marchisio AM, Marcello C, Mulas ML, Torelli S. 1987. Heterogeneity of muscarinic receptor in the developing human fetal brain: regional distribution and characterization. Early Hum Dev 15:165-177.
27. Haga K, Kameyama K, Haga T, Kikkawa U, Shiozaki K, Uchiyama H. 1996. Phosphorylation of human m1 muscarinic acetykholine receptors by G protein-coupled receptor kinase 2 and protein kinase C. J Biol Chem 271:2776-2782.
28. Heacock AM, Fisher SK, Agranoff BW. 1987. Enhanced coupling of neonatal muscarinic receptors in rat brain to phosphoinositide turnover. J Neurochem 48:1904-1911.
29. Hohmann CF, Berger-Sweeney JB. 1998. Cholinergic regulation of cortical development and plasticity. New twists to an old story. Prespect Dev Neurobiol 5:401-425.
30. Jope RS, Song L, Powers R. 1994. Agonist-induced, GTP-dependent phosphoinositide hydrolysis in post-mortem human brain membranes. J Neurochem 62:180-186.
31. Krejci AE, Tucek S. 2002. Quantification of mRNAs for M1 to M5 subtypes of muscarinic receptors in heart and brain cortex. Mol Pharmacol 61:1267-1272.
32. Krupnick JG, Benovic JL. 1998. The role of receptor kinases and arrestins in a G-protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol 38:289-319.
33. Larocca JN, Rodriguez-Gabin AG, Rashbaum WK, Weidenheim KM, Lyman WD. 1994. Muscarinic receptor-dependent activation of phospholipase C in the developing human fetal central nervous system. Brain Res 653:9-15.
34. Li X, Greenwood AF, Powers R, Jope RS. 1996. Effects of post-mortem interval, age and Alzheimer's disease on G-proteins in human brain. Neurobiol Aging 17:115-122.
35. 1 isoforms in post-mortem human brain caudate and cortical membranes: potential functional implications. Neurochem Int (in press).
36. Ostrom RS. 2002. New determinants of receptor-effector coupling: trafficking and compartmentation in membrane microdomains. Mol Pharmacol 61:473-476.
37. Ostrom RS, Post SR, Insel PA. 2000. Stoichiometry and compartmentation in G protein-coupled receptor signaling: implications for therapeutic interventions involving Gs. J Pharmacol Exp Ther 294:407-412.
38. Penela P, Alvarez-Doblado M, Muñoz A, Mayor F. 2000. Expression patterns of the regulatory proteins G protein-coupled receptor kinase 2 and beta-arrestin 1 during rat postnatal brain development: effect of hypothyroidism. Eur J Biochem 267:4390-4396.
39. Perry EK. 1986. The cholinergic hypothesis-ten years on. Br Med Bull 61:473-476.
40. Perry EK, Smith CJ, Atack JR, Candy JM, Johnson M, Perry RH. 1986. Neocortical cholinergic enzyme and receptor activities in the human fetal brain. J Neurochem 47:1262-1269.
41. 3H]quiniclidinyl benzilate binding sites in frontal cortex. J Neurochem 44:240-246.
42. Rhee SG, Bae YS. 1997. Regulation of phosphoinositide-specific phospholipase C isoenzymes. J Biol Chem 272:15045-15048.
43. Rodríguez-Puertas R, Pascual J, Pazos A. 1996. Effects of freezing storage time on the density of muscarinic receptors in the human post-mortem brain: an autoradiographic study in control and Alzheimer's disease brain tissues. Brain Res 728:65-71.
44. Rooney TA, Nahorski SR. 1987. Postnatal ontogeny of agonist depolarization-induced phosphoinositide hydrolysis in rat cerebral cortex. J Pharmacol Exp Ther 243:333-341.
45. Rooney TA, Nahorski SR. 1989. Developmental aspects of muscarinic-induced inositol polyphosphate accumulation in rat cerebral cortex. Eur J Pharmacol Mol Pharmacol Sect 172:425-434.
46. Ruiz de Azúa I, Lumbreras MA, Zalduegui A, Baamonde C, Dierssen M, Flórez J, Sallés J. 2001. Reduced phospholipase C-β activity and isoform expression in the cerebellum of Ts65Dn mouse: a model of Down syndrome. J Neurosci Res 66:540-550.
47. Sallés J, Wallace MA, Fain JN. 1993a. Differential effects of alkylating agents on the multiple muscarinic receptor subtypes linked to activation of phospholipase C by carbachol in rat brain cortical membranes. J Pharmacol Exp Ther 264:521-529.
48. Sallés J, Wallace MA, Fain JN. 1993b. Modulation of the phospholipase C activity in rat brain cortical membranes by simultaneous activation of distinct monoaminergic and cholinergic muscarinic receptors. Brain Res Mol Brain Res 20:111-117.
49. Sallés J, López de Jesús M, Goñi O, Fernandez-Teruel A, Driscoll P, Tobeña A, Escorihuela RM. 2001. Transmembrane signaling through phospholipase C in cortical and hippocampal membranes of psychogenetically selected rat lines. Psychopharmacology 154:115-125.
50. Shimohama S, Sumida Y, Fujimoto S, Matsuoka Y, Taniguchi T, Takenawa T, Kimura J. 1998. Differential expression of rat brain phospholipase C isoenzymes in development and aging. Biochem Biophys Res Commun 243:210-216.
51. Tice MAB, Hashemi T, Taylor LA, McQuade RD. 1996. Distribution of muscarinic receptor subtypes in rat brain from postnatal to old age. Brain Res Dev Brain Res 92:70-76.
52. Wall SJ, Yasuda RP, Li M, Ciesla W, Wolfe BB. 1992. The ontogeny of m1-m5 muscarinic receptor subtypes in rat forebrain. Brain Res Dev Brain Res 66:181-185.
53. Wallace MA, Claro E. 1990. Comparison of serotoninergic to muscarinic cholinergic stimulation of phosphoinositide-specific phospholipase C in rat brain cortical membranes. J Pharmacol Exp Ther 255:1296-1300.
54. Wallace MA, Claro E. 1993. Transmembrane signaling through phospholipase C in human brain membranes. Neurochem Res 18:139-145.
55. Watanabe M, Nakamura M, Sato K, Kano M, Simon MI, Inoue Y. 1998. Patterns of expression for the mRNA corresponding to the four isoforms of phospholipase C7beta; in mouse brain. Eur J Neurosci 10:2016-2025.
56. Watson N, Daniels DV, Ford APDW, Eglen RM, Hedge SS. 1999. Comparative pharmacology of recombinant M3 and M5 muscarinic receptors expressed in CHO-K1 cells. Br J Pharmacol 127:590-596.
57. Wei J, Walton EA, Milici A, Buccafusco JJ. 1994. m1-m5 muscarinic receptor distribution in rat CNS by RT-PCR and HPLC. J Neurochem 63:815-821.
58. Whitehouse PJ, Lynch D, Kuhar MJ. 1984. Effects of post-mortem delay and temperature on neurotransmitter receptor binding in a rat model of the human autopsy process. J Neurochem 43:553-559.
59. Yamada M, Mizuguchi M, Rhee SG, Kim SU. 1991. Development changes of three phosphoinositide-specific phospholipase C isoenzymes in the rat nervous system. Brain Res Dev Brain Res 59:7-16.