메뉴 건너뛰기




Volumn 5, Issue 6, 2006, Pages 601-607

Homozygous deletion of SMAD4 in breast cancer cell lines and invasive ductal carcinomas

Author keywords

Counting alleles; Homozygous deletion; Infiltrative ductal carcinoma; Laser capture microdissection; Signaling; TGF

Indexed keywords

SMAD4 PROTEIN;

EID: 33745778678     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.5.6.2660     Document Type: Article
Times cited : (25)

References (32)
  • 3
    • 0029834067 scopus 로고    scopus 로고
    • Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways
    • Lagna G, Hata A, Hemmati-Brivanlou A, Massague J. Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature 1996; 383:832-6.
    • (1996) Nature , vol.383 , pp. 832-836
    • Lagna, G.1    Hata, A.2    Hemmati-Brivanlou, A.3    Massague, J.4
  • 5
    • 0030667930 scopus 로고    scopus 로고
    • Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase
    • USA
    • Chen Y, Bhushan A, Vale W. Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase. Proc Natl Acad Sci USA 1997; 94:12938-43.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 12938-12943
    • Chen, Y.1    Bhushan, A.2    Vale, W.3
  • 6
    • 0031939744 scopus 로고    scopus 로고
    • Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12
    • Nishimura R, Kato Y, Chen D, Harris SE, Mundy GR, Yoneda T. Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12. J Biol Chem 1998; 273:1872-9.
    • (1998) J Biol Chem , vol.273 , pp. 1872-1879
    • Nishimura, R.1    Kato, Y.2    Chen, D.3    Harris, S.E.4    Mundy, G.R.5    Yoneda, T.6
  • 7
    • 0030460085 scopus 로고    scopus 로고
    • Cancer gets Mad: DPC4 and other TGFbeta pathway genes in human cancer
    • Moskaluk CA, Kern SE. Cancer gets Mad: DPC4 and other TGFbeta pathway genes in human cancer. Biochim Biophys Acta 1996; 1288:M31-3.
    • (1996) Biochim Biophys Acta , vol.1288
    • Moskaluk, C.A.1    Kern, S.E.2
  • 8
    • 0037757793 scopus 로고    scopus 로고
    • Role of Smad4 (DPC4) inactivation in human cancer
    • Miyaki M, Kuroki T. Role of Smad4 (DPC4) inactivation in human cancer. Biochem Biophys Res Commun 2003; 306:799-804.
    • (2003) Biochem Biophys Res Commun , vol.306 , pp. 799-804
    • Miyaki, M.1    Kuroki, T.2
  • 10
    • 0031441041 scopus 로고    scopus 로고
    • Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]- anthracene
    • Bottinger EP, Jakubczak JL, Haines DC, Bagnall K, Wakefield LM. Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene. Cancer Res 1997; 57:5564-70.
    • (1997) Cancer Res , vol.57 , pp. 5564-5570
    • Bottinger, E.P.1    Jakubczak, J.L.2    Haines, D.C.3    Bagnall, K.4    Wakefield, L.M.5
  • 13
    • 0027421280 scopus 로고
    • Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis
    • Fynan TM, Reiss M. Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis. Crit Rev Oncog 1993; 4:493-540.
    • (1993) Crit Rev Oncog , vol.4 , pp. 493-540
    • Fynan, T.M.1    Reiss, M.2
  • 15
    • 1842481404 scopus 로고    scopus 로고
    • Missense mutations of MADH4: Characterization of the mutational hot spot and functional consequences in human tumors
    • Iacobuzio-Donahue CA, Song J, Parmiagiani G, Yeo CJ, Hruban RH, Kern SE. Missense mutations of MADH4: Characterization of the mutational hot spot and functional consequences in human tumors. Clin Cancer Res 2004; 10:1597-604.
    • (2004) Clin Cancer Res , vol.10 , pp. 1597-1604
    • Iacobuzio-Donahue, C.A.1    Song, J.2    Parmiagiani, G.3    Yeo, C.J.4    Hruban, R.H.5    Kern, S.E.6
  • 19
    • 0037179848 scopus 로고    scopus 로고
    • A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer
    • Chen C, Bhalala HV, Qiao H, Dong JT. A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer. Oncogene 2002; 21:6567-72.
    • (2002) Oncogene , vol.21 , pp. 6567-6572
    • Chen, C.1    Bhalala, H.V.2    Qiao, H.3    Dong, J.T.4
  • 20
    • 0035066018 scopus 로고    scopus 로고
    • Early distant relapse in 'node-negative' breast cancer patients is not predicted by occult axillary lymph node metastases, but by the features of the primary tumor
    • Colpaert C, Vermeulen P, Jeuris W, van Beest P, Goovaerts G, Weyler J, Van Dam P, Dirix L, Van Marck E. Early distant relapse in 'node-negative' breast cancer patients is not predicted by occult axillary lymph node metastases, but by the features of the primary tumor. J Pathol 2001; 193:442-9.
    • (2001) J Pathol , vol.193 , pp. 442-449
    • Colpaert, C.1    Vermeulen, P.2    Jeuris, W.3    Van Beest, P.4    Goovaerts, G.5    Weyler, J.6    Van Dam, P.7    Dirix, L.8    Van Marck, E.9
  • 21
    • 4143120078 scopus 로고    scopus 로고
    • P surgical margin and gleason score as predictors of post-operative recurrence in prostate cancer with or without chromosome 8p allelic imbalance
    • in press
    • Zhou W, Goodman M, Lyles R, Lim S, Williams T, Rusthoven K, Mandel J, Amin M, JA. P surgical margin and gleason score as predictors of post-operative recurrence in prostate cancer with or without chromosome 8p allelic imbalance. The Prostate 2004, (in press).
    • (2004) The Prostate
    • Zhou, W.1    Goodman, M.2    Lyles, R.3    Lim, S.4    Williams, T.5    Rusthoven, K.6    Mandel, J.7    Amin, M.8    Ao, J.9
  • 25
    • 0034660862 scopus 로고    scopus 로고
    • Genome-wide search for loss of heterozygosity using laser capture microdissected tissue of breast carcinoma: An implication for mutator phenotype and breast cancer pathogenesis
    • Shen CY, Yu JC, Lo YL, Kuo CH, Yue CT, Jou YS, Huang CS, Lung JC, Wu CW. Genome-wide search for loss of heterozygosity using laser capture microdissected tissue of breast carcinoma: An implication for mutator phenotype and breast cancer pathogenesis. Cancer Res 2000; 60:3884-92.
    • (2000) Cancer Res , vol.60 , pp. 3884-3892
    • Shen, C.Y.1    Yu, J.C.2    Lo, Y.L.3    Kou, C.H.4    Yue, C.T.5    Jou, Y.S.6    Huang, C.S.7    Lung, J.C.8    Wu, C.W.9
  • 27
    • 0037081179 scopus 로고    scopus 로고
    • Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: A tissue microarray study
    • Xie W, Mertens JC, Reiss DJ, Rimm DL, Camp RL, Haffty BG, Reiss M. Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: A tissue microarray study. Cancer Res 2002; 62:497-505.
    • (2002) Cancer Res , vol.62 , pp. 497-505
    • Xie, W.1    Mertens, J.C.2    Reiss, D.J.3    Rimm, D.L.4    Camp, R.L.5    Haffty, B.G.6    Reiss, M.7
  • 30
    • 0034468328 scopus 로고    scopus 로고
    • Transforming growth factor-beta and breast cancer: Lessons learned from genetically altered mouse models
    • Wakefield LM, Yang YA, Dukhanina O. Transforming growth factor-beta and breast cancer: Lessons learned from genetically altered mouse models. Breast Cancer Res 2000; 2:100-6.
    • (2000) Breast Cancer Res , vol.2 , pp. 100-106
    • Wakefield, L.M.1    Yang, Y.A.2    Dukhanina, O.3
  • 31
    • 0034612789 scopus 로고    scopus 로고
    • Role of transforming growth factor-beta signaling in cancer
    • de Caestecker MP, Piek E, Roberts AB. Role of transforming growth factor-beta signaling in cancer. J Natl Cancer Inst 2000; 92:1388-402.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1388-1402
    • De Caestecker, M.P.1    Piek, E.2    Roberts, A.B.3
  • 32
    • 0032213514 scopus 로고    scopus 로고
    • Transforming growth factor beta type I receptor kinase mutant associated with metastatic breast cancer
    • Chen T, Carter D, Garrigue-Antar L, Reiss M. Transforming growth factor beta type I receptor kinase mutant associated with metastatic breast cancer. Cancer Res 1998; 58:4805-10.
    • (1998) Cancer Res , vol.58 , pp. 4805-4810
    • Chen, T.1    Carter, D.2    Garrigue-Antar, L.3    Reiss, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.