Therapeutic potential of madecassoside in transgenic mice of amyotrophic lateral sclerosis

Chinese Traditional and Herbal Drugs

Volumn 37, Issue 5, 2006, Pages 718-721

  Liu, Ying Ju ^a,b   Kobayashi, Yuta ^b   Li, Song Hua ^b   Gao, Li Jia ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b SHIMANE UNIVERSITY   (Japan)

Author keywords

Amyotrophic lateral sclerosis (ALS); Cu, Zn superoxide dismutase (SODI); Madecassoside

Indexed keywords

CHINESE DRUG; COPPER; MADECASSOSIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; ZINC;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DEATH; HISTOLOGY; LUMBAR SPINAL CORD; MOTONEURON; MOTOR DYSFUNCTION; MOUSE; MUSCLE STRENGTH; MUTANT; NERVE CELL DEGENERATION; NISSL SUBSTANCE; NONHUMAN; PROTEIN EXPRESSION; SURVIVAL; TRANSGENIC MOUSE;

EID: 33745766695     PISSN: 02532670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Yoshihara T, Ishigaki S. Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis [J]. J Neurochem, 2002, 80(1): 158-167.
2. Mhatre M, Floyd R A, Hensley K. Oxidative stress and neuroinflammation in Alzheimer's disease and amyotrophic lateral sclerosis: common links and potential therapeutic targets [J]. J Alzheimers Dis, 2004, 6(2): 147-157.
3. Qin L P, Zhuang W G, Zheng H C. Progress in the study on centella asiatica [J]. World Phytomed, 1997, 12(4): 154-157.
4. Ming Z J, Sun M. Study on anti-inflammation effect of asiaticoside [J]. Chin J Tradit Med Sci Technol, 2002, 9(1): 62.
5. Inhee M J, Ji-Eun S, Sung H Y. Protective effects of asiaticoside derivatives against beta-amyloid neurotoxicity [J]. J Neurosci Res, 1999, 58(3): 417-425.
6. Chen B W, Ji B A, Zhang X Z, et al. Protection of titracted extract of centella asiatica on gastric mucosa and its possible mechanism [J]. Chin J Dig, 1999, 19(4): 246-248.
7. Azzouz M, Ralph G S, Storkebaum E, et al. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS mode [J]. Nature, 2004, 429: 413-417.
8. Rowland L P. Merritt's Textbook of Neurology [M]. Philadelphia: Williams & Wilkins, 1995.
9. Brown R H Jr. Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice [J]. Cell, 1995, 80: 687-692.
10. Gurney M E, Cutting F B, Zhai P, et al. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis [J]. Ann Neurol, 1996, 39: 147-157.