A practical regiospecific synthesis of 9-nitrocamptothecin

Synthesis

Volumn , Issue 12, 2006, Pages 1940-1942

  Fu, Qingquan ^a,b   Chen, Zhiyong ^a  

^a CHENGDU INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

9 nitrocamptothecin; Nitration; Reduction of sulfonate

Indexed keywords

NITRATION; NITROGEN COMPOUNDS; REDUCTION; TUMORS;

9-NITROCAMPTOTHECIN; REDUCTION OF SULFONATE;

SYNTHESIS (CHEMICAL);

10 HYDROXYCAMPTOTHECIN; 9 NITRO 10 (4 TOLUENESULFONYL)CAMPTOTHECIN; 9 NITRO 10 HYDROXYCAMPTOTHECIN; CAMPTOTHECIN DERIVATIVE; RUBITECAN; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG SYNTHESIS; REDUCTION;

EID: 33745749456     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-942359     Document Type: Article

References (8)

1. Wall, M. E.; Wani, M. C.; Cook, C. E.; Palmer, K. H.; McPhail, A. T.; Sim, G. A. J. Am. Chem. Soc. 1966, 88, 3888.
2. Hsiang, Y.-H.; Hertzberg, R.; Hecht, S.; Liu, L. F. J. Biol. Chem. 1985, 260, 4873.
3. (a) Wani, M. C.; Nicholas, A. W.; Wall, M. E. J. Med. Chem. 1986, 29, 2358.
4. (b) Cao, Z.; Amstrong, K.; Shaw, M.; Petry, E.; Harris, N. Synthesis 1998, 1724.
5. (c) Puri, S. C.; Handa, G.; Suri, O. P.; Qazi, G. N. Synth. Commun. 2004, 34, 3443.
6. Cabri, W.; Candiani, I.; Zarini, F.; Penco, S.; Bedeschi, A. Tetrahedron Lett. 1995, 36, 9197.
7. Cacchi; S.; Ciattini, P. G.; Morera, E.; Ortar, G. Tetrahedron Lett. 1986, 27, 5541.
8. Wood, J. L.; Fortuak, J. M.; Mastrocola, A. R.; Mellinger, M.; Burk, P. L. J. Org. Chem. 1995, 60, 5739.