Oxidative stress induced by methotrexate alone and in the presence of methanol in discrete regions of the rodent brain, retina and optic nerve

Toxicology Letters

Volumn 165, Issue 3, 2006, Pages 265-273

  Rajamani, Rathinam ^a   Muthuvel, Arumugham ^a   Senthilvelan, Manohar ^a   Sheeladevi, Rathinasamy ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Brain; Folate deficiency; HSP70; MeOH; Methotrexate; Oxidative stress; Thiols

Indexed keywords

CARBONYL DERIVATIVE; CATALASE; FOLIC ACID; FREE RADICAL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEAT SHOCK PROTEIN 70; METHANOL; METHOTREXATE; SCAVENGER; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN CORTEX; CEREBELLUM; CONTROLLED STUDY; HIPPOCAMPUS; HYPOTHALAMUS; LIPID PEROXIDATION; MALE; MEDULLA OBLONGATA; MESENCEPHALON; NONHUMAN; OPTIC NERVE; OXIDATIVE STRESS; PONS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; RETINA; RODENT; WESTERN BLOTTING;

ANIMALS; BRAIN; CATALASE; DRUG THERAPY, COMBINATION; FORMIC ACIDS; FORMIMINOGLUTAMIC ACID; GENE EXPRESSION REGULATION; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HSP70 HEAT-SHOCK PROTEINS; LIPID PEROXIDATION; MALE; METHANOL; METHOTREXATE; OPTIC NERVE; OXIDATIVE STRESS; RATS; RATS, WISTAR; RETINA; SULFHYDRYL COMPOUNDS; SUPEROXIDE DISMUTASE;

ANIMALIA; RODENTIA;

EID: 33745740219     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2006.05.005     Document Type: Article

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