Macrophage cultures are susceptible to lytic productive infection by endothelial-cell-propagated human cytomegalovirus strains and present viral IE1 protein to CD4+ T cells despite late downregulation of MHC class II molecules

Journal of General Virology

Volumn 87, Issue 7, 2006, Pages 1853-1862

  Sinzger, Christian ^a   Eberhardt, Kathrin ^a   Cavignac, Yolaine ^a   Weinstock, Christof ^a   Kessler, Tobias ^a   Jahn, Gerhard ^a   Davignon, Jean Luc ^b  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b CHU PURPAN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN IE1; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS PROTEIN;

ANTIGEN PRESENTATION; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIVISION; CELL SURFACE; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DOWN REGULATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNE RESPONSE; MACROPHAGE FUNCTION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; T LYMPHOCYTE ACTIVATION; TARGET CELL; VIRUS IDENTIFICATION; VIRUS STRAIN; VIRUS VIRULENCE;

ANTIGEN PRESENTATION; ANTIGENS, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; CYTOPATHOGENIC EFFECT, VIRAL; DOWN-REGULATION; ENDOTHELIAL CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMMEDIATE-EARLY PROTEINS; KINETICS; LYMPHOCYTE ACTIVATION; MACROPHAGES; MONOCYTES; VIRAL PROTEINS; VIRUS CULTIVATION; VIRUS REPLICATION;

HUMAN HERPESVIRUS 5;

EID: 33745629322     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.81595-0     Document Type: Article

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