-
2
-
-
0035007855
-
Chemotherapy in elderly patients with colorectal cancer
-
Kohne CH, Grothey A, Bokemeyer C et al. Chemotherapy in elderly patients with colorectal cancer. Ann Oncol 2001 12: 435-442.
-
(2001)
Ann Oncol
, vol.12
, pp. 435-442
-
-
Kohne, C.H.1
Grothey, A.2
Bokemeyer, C.3
-
3
-
-
0033782674
-
Risk factors determining chemotherapeutic toxicity in patients with advanced colorectal cancer
-
Jansman FG, Sleijfer DT, Coenen JL et al. Risk factors determining chemotherapeutic toxicity in patients with advanced colorectal cancer, Drug Saf 2000; 23: 255-278.
-
(2000)
Drug Saf
, vol.23
, pp. 255-278
-
-
Jansman, F.G.1
Sleijfer, D.T.2
Coenen, J.L.3
-
4
-
-
0344109583
-
Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer
-
Meta-Analysis Group in Cancer
-
Meta-Analysis Group in Cancer. Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. J Clin Oncol 1998; 6: 301-308.
-
(1998)
J Clin Oncol
, vol.6
, pp. 301-308
-
-
-
5
-
-
0031444484
-
Chemotherapy of colorectal cancer: History and new themes
-
Bertino GR. Chemotherapy of colorectal cancer: History and new themes. Semin Oncol 1997; 24 (Suppl 18): S18-37.
-
(1997)
Semin Oncol
, vol.24
, Issue.SUPPL. 18
-
-
Bertino, G.R.1
-
6
-
-
0034727063
-
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
-
Irinotecan Study Group
-
Saltz L, Cox JV, Blanke C et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group. N Engl J Med 2000; 343: 905-914.
-
(2000)
N Engl J Med
, vol.343
, pp. 905-914
-
-
Saltz, L.1
Cox, J.V.2
Blanke, C.3
-
7
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicenter randomised trial
-
Douillard JV, Cunningham D, Roth A et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicenter randomised trial. Lancet 2000; 355: 1041-1047.
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.V.1
Cunningham, D.2
Roth, A.3
-
8
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
De Gramont A, Figer A, Seymour M et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000; 18: 2938-2947.
-
(2000)
J Clin Oncol
, vol.18
, pp. 2938-2947
-
-
De Gramont, A.1
Figer, A.2
Seymour, M.3
-
9
-
-
0033989203
-
Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first line treatment of metastatic colorectal cancer
-
Giacchetti S, Zidani R, Perpoint B et al. Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first line treatment of metastatic colorectal cancer. J Clin Oncol 2000; 18: 136-147.
-
(2000)
J Clin Oncol
, vol.18
, pp. 136-147
-
-
Giacchetti, S.1
Zidani, R.2
Perpoint, B.3
-
10
-
-
24644457747
-
Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter study of the Gruppo Oncologico dell'Italia Meridionale
-
Colucci G, Gebbia V, Paoletti G et al. Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter study of the Gruppo Oncologico dell'Italia Meridionale. J Clin Oncol 2005; 23: 4866-4875.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4866-4875
-
-
Colucci, G.1
Gebbia, V.2
Paoletti, G.3
-
11
-
-
0033103493
-
Raltitrexed (Tomudex) in combination treatment for colorectal cancer: New perspectives
-
Van Cutsem E. Raltitrexed (Tomudex) in combination treatment for colorectal cancer: New perspectives. Eur J Cancer 1999; 35 (Suppl 1): S1-S5.
-
(1999)
Eur J Cancer
, vol.35
, Issue.SUPPL. 1
-
-
Van Cutsem, E.1
-
12
-
-
0035986787
-
Raltitrexed (Tomudex): An alternative choice in patients intolerant to 5-fluorouracil
-
Kempin S, Gutierez J, Wilson E et al. Raltitrexed (Tomudex): An alternative choice in patients intolerant to 5-fluorouracil. Cancer Invest 2002; 20: 992-995.
-
(2002)
Cancer Invest
, vol.20
, pp. 992-995
-
-
Kempin, S.1
Gutierez, J.2
Wilson, E.3
-
13
-
-
0037317004
-
Thymidylate synthase expression in advanced colorectal cancer predicts for response to raltitrexed
-
Farruggia DC, Ford HE, Cunningham D et al. Thymidylate synthase expression in advanced colorectal cancer predicts for response to raltitrexed. Clin Cancer Res 2003; 9: 792-801.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 792-801
-
-
Farruggia, D.C.1
Ford, H.E.2
Cunningham, D.3
-
14
-
-
9044245305
-
ZD1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer
-
Tomudex Colorectal Study Group
-
Zalcberg JR, Cunningham D, Van Cutsem E et al. ZD1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer. Tomudex Colorectal Study Group. J Clin Oncol 1996; 14: 716-721.
-
(1996)
J Clin Oncol
, vol.14
, pp. 716-721
-
-
Zalcberg, J.R.1
Cunningham, D.2
Van Cutsem, E.3
-
15
-
-
27944435401
-
Phase II randomised trial of raltitrexed-oxaliplatin vs raltitrexed-irinotecan as first-line treatment in advanced colorectal cancer
-
Feliu J, Castanon C, Salud A et al. Phase II randomised trial of raltitrexed-oxaliplatin vs raltitrexed-irinotecan as first-line treatment in advanced colorectal cancer. Br J Cancer 2005; 93: 1230-1235.
-
(2005)
Br J Cancer
, vol.93
, pp. 1230-1235
-
-
Feliu, J.1
Castanon, C.2
Salud, A.3
-
16
-
-
0036696469
-
Toxicity analysis of the 5-day bolus 5-fluorouracil/folinic acid regimen for the treatment of colorectal carcinoma from 2 randomized controlled trials: A concern about dose
-
Vincent M, Ho C, Tomiak A et al. Toxicity analysis of the 5-day bolus 5-fluorouracil/folinic acid regimen for the treatment of colorectal carcinoma from 2 randomized controlled trials: A concern about dose. Clin Colorectal Cancer 2002; 2: 111-118.
-
(2002)
Clin Colorectal Cancer
, vol.2
, pp. 111-118
-
-
Vincent, M.1
Ho, C.2
Tomiak, A.3
-
17
-
-
0034569558
-
Schedule-dependent interaction between raltitrexed and 5-fluorouracil in human colon cancer cell lines in vitro
-
Kano Y, Akutsu M, Suzuki K et al. Schedule-dependent interaction between raltitrexed and 5-fluorouracil in human colon cancer cell lines in vitro. Oncol Res 2000; 12: 137-148.
-
(2000)
Oncol Res
, vol.12
, pp. 137-148
-
-
Kano, Y.1
Akutsu, M.2
Suzuki, K.3
-
18
-
-
0036235187
-
Raltitrexed: Current clinical status and future directions
-
Van Cutsem E, Cunningham D, Maroun J et al. Raltitrexed: Current clinical status and future directions. Ann Oncol 2002; 13: 513-522.
-
(2002)
Ann Oncol
, vol.13
, pp. 513-522
-
-
Van Cutsem, E.1
Cunningham, D.2
Maroun, J.3
-
19
-
-
1842532001
-
Phase I trial of sequential raltitrexed followed by bolus 5-fluorouracil in patients with advanced colorectal cancer
-
Schwartz GK, Bertino J, Kemeny N et al. Phase I trial of sequential raltitrexed followed by bolus 5-fluorouracil in patients with advanced colorectal cancer. Anticancer Drugs 2004; 15: 219-227.
-
(2004)
Anticancer Drugs
, vol.15
, pp. 219-227
-
-
Schwartz, G.K.1
Bertino, J.2
Kemeny, N.3
-
20
-
-
0034914634
-
Raltitrexed/5-fluorouracil-based combination chemotherapy regimens in anticancer therapy
-
Caponigro F Avallone A, Budillon A et al. Raltitrexed/ 5-fluorouracil-based combination chemotherapy regimens in anticancer therapy. Anticancer Drugs 2001; 12: 489-497.
-
(2001)
Anticancer Drugs
, vol.12
, pp. 489-497
-
-
Caponigro, F.1
Avallone, A.2
Budillon, A.3
-
21
-
-
0033397854
-
Quality-of-life assessment in colorectal cancer patients: Evaluation of cancer therapies
-
Sprangers MA. Quality-of-life assessment in colorectal cancer patients: evaluation of cancer therapies. Semin Oncol 1999; 26: 691-696.
-
(1999)
Semin Oncol
, vol.26
, pp. 691-696
-
-
Sprangers, M.A.1
-
22
-
-
0036270715
-
Raltitrexed in the treatment of elderly patients with advanced colorectal cancer: An active and low toxicity regimen
-
Feliu J, Mel JR, Camps C et al. Raltitrexed in the treatment of elderly patients with advanced colorectal cancer: An active and low toxicity regimen. Eur J Cancer 2002; 38: 1204-1211.
-
(2002)
Eur J Cancer
, vol.38
, pp. 1204-1211
-
-
Feliu, J.1
Mel, J.R.2
Camps, C.3
-
23
-
-
0036186018
-
Efficacy, tolerability and management of raltitrexed (Tomudex) monatherapy in patients with advanced colorectal cancer. A review of phase II/III trials
-
Cunningham D, Zalcberg J, Maroun J et al. Efficacy, tolerability and management of raltitrexed (Tomudex) monatherapy in patients with advanced colorectal cancer. A review of phase II/III trials. Eur J Cancer 2002; 38: 478-486.
-
(2002)
Eur J Cancer
, vol.38
, pp. 478-486
-
-
Cunningham, D.1
Zalcberg, J.2
Maroun, J.3
-
24
-
-
0041885257
-
Favorable toxicity profile of raltitrexed in elderly patients treated for colorectal cancer: A case series
-
Franchi F, Pastore C, Caporale A et al. Favorable toxicity profile of raltitrexed in elderly patients treated for colorectal cancer: A case series. Gerontology 2003; 49: 324-327.
-
(2003)
Gerontology
, vol.49
, pp. 324-327
-
-
Franchi, F.1
Pastore, C.2
Caporale, A.3
-
25
-
-
0033103659
-
Raltitrexed (Tomudex) in combination with 5-fluorouracil for the treatment of patients with advanced colorectal cancer: Preliminary results from phase I clinical trials
-
Schwarzt GK, Harstrick A, Gonzalez Baron M. Raltitrexed (Tomudex) in combination with 5-fluorouracil for the treatment of patients with advanced colorectal cancer: Preliminary results from phase I clinical trials. Eur J Cancer 1999; 35 (Suppl 1): S9-S13.
-
(1999)
Eur J Cancer
, vol.35
, Issue.SUPPL. 1
-
-
Schwarzt, G.K.1
Harstrick, A.2
Gonzalez Baron, M.3
-
26
-
-
1842532001
-
Phase I trial of sequential raltitrexed followed by bolus 5-fluorouracil in patients with advanced colorectal cancer
-
Schwartz GK, Bertino J, Kemeny N et al. Phase I trial of sequential raltitrexed followed by bolus 5-fluorouracil in patients with advanced colorectal cancer. Anticancer Drugs 2004; 15: 219-222.
-
(2004)
Anticancer Drugs
, vol.15
, pp. 219-222
-
-
Schwartz, G.K.1
Bertino, J.2
Kemeny, N.3
-
27
-
-
0033372553
-
Phase I and pharmacokinetic study of tomudex combined with 5-fluorouracil plus levofolinic acid in advanced head and neck cancer and colorectal cancer
-
Caponigro F, Avallone A, Mc Leod H et al. Phase I and pharmacokinetic study of tomudex combined with 5-fluorouracil plus levofolinic acid in advanced head and neck cancer and colorectal cancer. Clin Cancer Res 1999; 5: 3948-3955.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 3948-3955
-
-
Caponigro, F.1
Avallone, A.2
Mc Leod, H.3
-
28
-
-
0033768349
-
Biweekly irinotecan or raltitrexed plus 6S-leucovorin and bolus 5-fluorouracil in advanced colorectal carcinoma: A Southern Italy Cooperative Oncology Group phase II-III randomized trial
-
Comella P, De Vita F, Mancarella S et al. Biweekly irinotecan or raltitrexed plus 6S-leucovorin and bolus 5-fluorouracil in advanced colorectal carcinoma: A Southern Italy Cooperative Oncology Group phase II-III randomized trial. Ann Oncol 2000; 11: 1323-1333.
-
(2000)
Ann Oncol
, vol.11
, pp. 1323-1333
-
-
Comella, P.1
De Vita, F.2
Mancarella, S.3
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