Polymorphisms of TNF microsatellite marker a and HLA-DR-DQ in diabetes mellitus-a study in 609 Swedish subjects

Human Immunology

Volumn 67, Issue 7, 2006, Pages 527-534

  Törn, Carina ^a   Hillman, Magnus ^a   Sanjeevi, Carani B ^b   Landin Olsson, Mona ^a  

^a LUND UNIVERSITY   (Sweden)

^b Department of Molecular Medicine   (Sweden)

Author keywords

autoimmunity; Genetic predisposition; risk

Indexed keywords

HLA DQ ANTIGEN; HLA DQ2 ANTIGEN; HLA DQ8 ANTIGEN; HLA DR ANTIGEN; HLA DR3 ANTIGEN; HLA DR4 ANTIGEN; INSULIN; OLIGONUCLEOTIDE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOIMMUNE DISEASE; CHILD; CONFIDENCE INTERVAL; CONTROLLED STUDY; DISEASE CLASSIFICATION; GENETIC MARKER; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK FACTOR; SWEDEN;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; GENE FREQUENCY; GENOTYPE; HLA-DQ ANTIGENS; HLA-DR3 ANTIGEN; HLA-DR4 ANTIGEN; HUMANS; LINKAGE DISEQUILIBRIUM; MICROSATELLITE REPEATS; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS; SWEDEN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33745614285     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2006.04.002     Document Type: Article

References (37)

1. Noble J.A., Valdes A.M., Cook M., Klitz W., Thomson G., and Erlich H.A. The role of HLA class II genes in insulin-dependent diabetes mellitus. molecular analysis of 180 Caucasian, multiplex families. Am J Hum Genet 59 (1996) 1134
2. Lambert A.P., Gillespie K.M., Thomson G., Cordell H.J., Todd J.A., Gale E.A., and Bingley P.J. Absolute risk of childhood-onset type 1 diabetes defined by human leukocyte antigen class II genotype. A population-based study in the United Kingdom. J Clin Endocrinol Metab 89 (2004) 4037
3. Steck A.K., Bugawan T.L., Valdes A.M., Emery L.M., Blair A., Norris J.M., Redondo M.J., Babu S.R., Erlich H.A., Eisenbarth G.S., and Rewers M.J. Association of non-HLA genes with Type 1 diabetes autoimmunity. Diabetes 54 (2005) 2482
4. Jongeneel C.V., Briant L., Udalova I.A., Sevin A., Nedospasov S.A., and Cambon-Thomsen A. Extensive genetic polymorphism in the human tumor necrosis factor region and relation to extended HLA haplotypes. Proc Natl Acad Sci USA 88 (1991) 9717
5. Nedospasov S.A., Udalova I.A., Kuprash D.V., and Turetskaya R.L. DNA sequence polymorphism at the human tumor necrosis factor (TNF) locus. Numerous TNF/lymphotoxin alleles tagged by two closely linked microsatellites in the upstream region of the lymphotoxin (TNF-beta) gene. J Immunol 147 (1991) 1053
6. Udalova I.A., Nedospasov S.A., Webb G.C., Chaplin D.D., and Turetskaya R.L. Highly informative typing of the human TNF locus using six adjacent polymorphic markers. Genomics 16 (1993) 180
7. Obayashi H., Nakamura N., Fukui M., Tegoshi H., Fujii M., Ogata M., Hasegawa G., Shigeta H., Kitagawa Y., Nakano K., Kondo M., Fukui I., Maruya E., Saji H., Ohta M., and Nishimura M. Influence of TNF microsatellite polymorphisms (TNFa) on age-at-onset of insulin-dependent diabetes mellitus. Hum Immunol 60 (1999) 974
8. Crouau-Roy B., Briant L., Bouissou C., Stravropoulos C., Pociot F., Cambon-Thomsen A., and Clayton J. Tumor necrosis factor microsatellites in four European populations. Hum Immunol 38 (1993) 213
9. Ciusani E., Salmaggi A., Pociot F., Nespolo A., and Sandberg-Wollheim M. Tumour necrosis factor microsatellite alleles in an Italian population. Eur J Immunogenet 24 (1997) 9
10. Gallagher G., Eskdale J., Oh H.-H., Richards S.D., Campbell D.A., and Field M. Polymorphisms in the TNF gene cluster and MHC serotypes in the West of Scotland. Immunogenetics 45 (1997) 188
11. Gambelunghe G., Ghaderi M., Cosentino A., Falomi A., Brunetti P., Falorni A., and Sanjeevi C.B. Association of MHC Class I chain-related A (MIC-A) gene polymorphism with Type I diabetes. Diabetologia 43 (2000) 507
12. McManus R., Moloney M., Borton M., Finch A., Chuan Y.-T., Lawlor E., Weir D.G., and Kelleher D. Association of celiac disease with microsatellite polymorphisms close to the tumor necrosis factor genes. Hum Immunol 45 (1996) 24
13. Takeuchi F., Nabeta H., Hong G.H., Kawasugi K., Mori M., Matsuta K., Kuwata S., Murayama T., and Nakano K. The genetic contribution of the TNFa11 microsatellite allele and the TNFb + 252*2 allele in Japanese RA. Clin Exp Rheumatol 23 (2005) 494
14. Ghaderi M., Nikitina L., Peacock C.S., Hjelmström P., Hallmans G., Wiklund F., Lenner P., Blackwell J.M., Dillner J., and Sanjeevi C.B. Tumor necrosis factor a-11 and DR15-DQ6 (B*0602) haplotype increase the risk for cervical intraepithelial neoplasia in human papillomavirus 16 seropositive women in Northern Sweden. Cancer Epidemiol Biomarkers Prev 9 (2000) 1067
15. Makhatadze N.J. Tumor necrosis factor locus. genetic organisation and biological implications. Hum Immunol 59 (1998) 571
16. Kim K.A., Kim S., Chang I., Kim G.S., Min Y.K., Lee M.K., Kim K.W., and Lee M.S. IFN gamma/TNF alpha synergism in MHC class II induction. effect of nicotinamide on MHC class II expression but not on islet-cell apoptosis. Diabetologia 45 (2002) 385
17. Wilson A.G., Symons J.A., McDowell T.L., McDevitt H.O., and Duff G.W. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA 94 (1997) 3195
18. Peng J., Liu C., Zhu K., Zhu Y., Yu Y., Li J., Hou M., Chen X., Xu C., and Zhang M. The TNF2 allele is a risk factor to severe aplastic anemia independent of HLA-DR. Hum Immunol 64 (2003) 896
19. McGuire W., Hill A.V., Allsopp C.E., Greenwood B.M., and Kwiatkowski D. Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature 371 (1994) 508
20. Warzocha K., Ribeiro P., Bienvenu J., Roy P., Charlot C., Rigal D., Coiffier B., and Salles G. Genetic polymorphisms in the tumor necrosis factor locus influence non-Hodgkin's lymphoma outcome. Blood 91 (1998) 3574
21. Jacob C.O., Fronek Z., Lewis G.D., Koo M., Hansen J.A., and McDevitt H.O. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha. Relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci USA 87 (1990) 1233
22. Hotamisligil G.S., Murray D.L., Choy L.N., and Spiegelman B.M. Tumor necrosis factor alpha inhibits signaling from the insulin receptor. Proc Natl Acad Sci USA 91 (1994) 4854
23. Hotamisligil G.S., Arner P., Caro J.F., Atkinson R.L., and Spiegelman B.M. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 95 (1995) 2409
24. Kern P.A., Saghizadeh M., Ong J.M., Bosch R.J., Deem R., and Simsolo R.B. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 95 (1995) 2111
25. Landin-Olsson M., Sundkvist G., and Lernmark Å. Prolonged incubation in the two-colour immunofluorescence test increases the prevalence and titres of islet cell antibodies in Type 1 (insulin-dependent) diabetes mellitus. Diabetologia 30 (1987) 327
26. Verge C.F., Stenger D., Bonifacio E., Colman P.G., Pilcher C., Bingley P.J., and Eisenbarth G.S. Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes. Combinatorial Islet Autoantibody Workshop. Diabetes 47 (1998) 1857
27. Grubin C.E., Daniels T., Toivola B., Landin-Olsson M., Hagopian W.A., Li L., Karlsen A.E., Boel E., Michelsen B., and Lernmark Å. A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM. Diabetologia 37 (1994) 344
28. Falorni A.I., Örtqvist E., Persson B., and Lernmark Å. Radioimmunoassays for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands. J Immunol Methods 186 (1995) 89
29. Gianani R., Rabin D.U., Verge C.F., Yu L., Babu S.R., Pietropaolo M., and Eisenbarth G.S. ICA512 autoantibody radioassay. Diabetes 44 (1995) 1340
30. Bingley P.J., Bonifacio E., and Mueller P.W. Diabetes Antibody Standardization Program. First assay proficiency evaluation. Diabetes 52 (2003) 1128
31. Sanjeevi C.B., Seshiah V., Möller E., and Olerup O. Different genetic backgrounds for malnutrition-related diabetes and type 1 (insulin-dependent) diabetes mellitus in South Indians. Diabetologia 35 (1992) 283
32. Rønningen K.S., Iwe T., Halstensen T.S., Spurkland A., and Thorsby E. The amino acid at position 57 of the HLA-DQ beta chain and susceptibility to develop insulin-dependent diabetes mellitus. Hum Immunol 26 (1989) 215
33. Obayashi H., Hasegawa G., Fukui M., Kamiuchi K., Kitamura A., Ogata M., Kanaitsuka T., Shigeta H., Kitagawa Y., Nakano K., Nishimura M., Ohta M., and Nakamura N. Tumor necrosis factor microsatellite polymorphism influences the development of insulin dependency in adult-onset diabetes patients with the DRB1*1502-DQB1*0601 allele and anti-glutamic acid decarboxylase antibodies. J Clin Endocrinol Metab 85 (2000) 3348
34. Pociot F., Briant L., Jongeneel C.V., Mölvig J., Worsaae H., Abbal M., Thomsen M., Nerup J., and Cambon-Thomsen A. Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-alpha and TNF-beta by human mononuclear cells. a possible link to insulin-dependent diabetes mellitus. Eur J Immunol 23 (1993) 224
35. Hjelmström P., Peacock C.S., Giscombe R., Pirskanen R., Lefvert A.K., Blackwell J.M., and Sanjeevi C.B. Polymorphism in tumor necrosis factor genes associated with myasthenia gravis. J Neuroimmunol 88 (1998) 137
36. Hussain M.J., Maher J., Warnock T., Vats A., Peakman M., and Vergani D. Cytokine overproduction in healthy first degree relatives of patients with IDDM. Diabetologia 41 (1998) 343
37. Skarsvik S., Tiittanen M., Lindström A., Casas R., Ludvigsson J., and Vaarala O. Poor in vitro maturation and pro-inflammatory cytokine response of dendritic cells in children at genetic risk of type 1 diabetes. Scand J Immunol 60 (2004) 647