Synthesis and biodistribution studies of two novel radioiodinated areno-annelated estra-1,3,5(10), 16-tetraene-3-ols as promising estrogen receptor radioligands

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 49, Issue 6, 2006, Pages 559-569

  Oliveira, M C ^a   Videira, M ^a   Almeida, A ^a   Gano, L ^a   Watanabe, M ^b   Thiemann, T ^b   Santos, A C ^c   Botelho, F ^c   Oliveira, C ^d  

^a INSTITUTO TECNOLÓGICO E NUCLEAR   (Portugal)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Breast tumour imaging; Estradiol derivatives; Estrogen receptor; Radioiodination

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IODINE COMPOUNDS; MEDICAL IMAGING;

BIODISTRIBUTIONS; BREAST TUMOR IMAGING; ELECTROPHILIC AROMATIC SUBSTITUTIONS; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR; IN-VIVO; POTENTIAL LIGAND; RADIOIODINATION; RADIOLIGANDS; SYNTHESISED;

SODIUM IODIDE;

1 METHOXYBENZO(4,3 16,17)ESTRA 1,3,5,(10), 16 TETRAENE 3 OL; 2 IODO 1 METHOXYBENZO(4,3 16,17)ESTRA 1,3,5,(10), 16 TETRAENE 3 OL I 125; 4 IODO 1 METHOXYBENZO(4,3 16,17)ESTRA 1,3,5,(10), 16 TETRAENE 3 OL I 125; ESTRA 1,3,5 (10), 16 TETRAENE 3 OL DERIVATIVE; ESTROGEN RECEPTOR; IODINE 125; OXIDIZING AGENT; RADIOLIGAND; SODIUM IODIDE; TOSYLCHLORAMIDE SODIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HEPATOBILIARY SYSTEM; MOLECULAR BIOLOGY; NONHUMAN; RADIOCHEMISTRY; RADIOIODINATION; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; UTERUS;

EID: 33745609761     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1076     Document Type: Article

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