Exploring structural requirements for aldose-reductase inhibition by 2,4-dioxo-5-(naphth-2-ylmethylene)-3-thiazolidinyl acetic acids and 2-thioxo analogues: Fujita-Ban and Hansch approacth

Archiv der Pharmazie

Volumn 339, Issue 6, 2006, Pages 327-331

  Soni, Love Kumar ^a   Kaskhedikar, Satish G ^a  

^a SHRI G S INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

2,4 Dioxo 5 (naphth 2 ylmethylene) 3 thiazolidinyl acetic acid; 2 Thioxo analogues; Aldose reductase; Fujita Ban analysis; Quantitative structure activity relationships analysis

Indexed keywords

2 THIOXO 4 OXO 3 THIAZOLIDINYL ACETIC ACID DERIVATIVE; 2 THIOXO ANALOGUE; 2,4 DIOXO 5 (NAPHTH 2 YLMETHYLENE) 3 THIAZOLIDINYL ACETIC ACID DERIVATIVE; 3 THIAZOLIDINYL ACETIC ACID DERIVATIVE; ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHEMICAL STRUCTURE; DRUG BINDING; DRUG INHIBITION; ENZYME INHIBITION; HYDROPHOBICITY; IC 50; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ACETIC ACIDS; ALDEHYDE REDUCTASE; DRUG DESIGN; ENZYME INHIBITORS; MODELS, STRUCTURAL; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN CONFORMATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 33745537057     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200500015     Document Type: Article

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