Quantitative structure-activity analysis of 5-arylidene-2,4- thiazolidinediones as aldose reductase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 3, 2006, Pages 512-520

  Sambasivarao, S V ^a   Soni, Love K ^a   Gupta, Arun K ^a   Hanumantharao, P ^a   Kaskhedikar, S G ^a  

^a CADD Laboratory   (India)

Author keywords

2,4 Thiazolidinediones; Aldose reductase inhibitors; Diabetes mellitus; Fujita Ban analysis; Hansch analysis; Quantitative structure activity relationship

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ACETIC ACID; ALDOSE REDUCTASE INHIBITOR;

AMINO ACID SUBSTITUTION; ANALYTIC METHOD; ARTICLE; DRUG DESIGN; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

ALDEHYDE REDUCTASE; ANIMALS; BINDING SITES; CATTLE; DIABETES MELLITUS; ENZYME INHIBITORS; HYPOGLYCEMIC AGENTS; INHIBITORY CONCENTRATION 50; LENS, CRYSTALLINE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINEDIONES;

EID: 29544446591     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.10.069     Document Type: Article

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