Controlled study of enteral arginine supplementation in burned children: impact on immunologic and metabolic status

Nutrition

Volumn 22, Issue 7-8, 2006, Pages 705-712

  Marin, Veronica B ^a   Rodriguez Osiac, Lorena ^a   Schlessinger, Liana ^a   Villegas, Jorge ^b   Lopez, Marcelo ^a   Castillo Duran, Carlos ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b HOSPITAL LUIS CALVO MACKENNA   (Chile)

Author keywords

Arginine; Burn; Children; Enteral nutrition; Immune response; Metabolic response

Indexed keywords

ALBUMIN; ARGININE; C REACTIVE PROTEIN; GLUCOSE; INTERLEUKIN 1; INTERLEUKIN 6; MITOGENIC AGENT; NITROGEN; NITROGEN DERIVATIVE; ORNITHINE; PLACEBO; PREALBUMIN; TUMOR NECROSIS FACTOR ALPHA;

ANALYSIS OF COVARIANCE; ARTICLE; BODY SURFACE; BURN; CALORIC INTAKE; CHILD; CHILE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; ENTERIC FEEDING; FEMALE; HUMAN; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MALE; METABOLISM; NITROGEN URINE LEVEL; PEDIATRIC HOSPITAL; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE;

AMINO ACIDS; ARGININE; BLOOD GLUCOSE; BURNS; C-REACTIVE PROTEIN; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; ENTERAL NUTRITION; HUMANS; INFANT; INTERLEUKIN-6; LYMPHOCYTE ACTIVATION; ORNITHINE; PLACEBOS; PREALBUMIN; SERUM ALBUMIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33745385520     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nut.2006.03.009     Document Type: Article

References (47)

1. Barak N., Wall-Alonso E., and Sitrin M. Evaluation of stress factors and body weight adjustments currently used to estimate energy expenditure in hospitalized patients. JPEN 26 (2002) 231-238
2. Coss-Bu J.A., Jefferson L.S., Walding D., David Y., Smith E.O., and Klish W.J. Resting energy expenditure and nitrogen balance in critically ill pediatric patient on mechanical ventilation. Nutrition 14 (1998) 649-652
3. Milner E.A., Cioffi W.G., Mason Jr. A.D., McManus W.F., and Pruitt Jr. B.A. Accuracy of urinary nitrogen for predicting total urinary nitrogen in thermally injured patients. JPEN 17 (1993) 414-416
4. Tredget E.E., and Yu Y.M. The metabolic effects of thermal injury. World J Surg 16 (1992) 68-79
5. Askarian M., Hosseini R.S., Kheirandish P., and Assadian O. Incidence and outcome of nosocomial infections in female burn patients in Shiraz, Iran. Am J Infect Control 32 (2004) 23-26
6. Zedler S., Bone R.C., Baue A.E., von Donnersmarck G.H., and Faist E. T-cell reactivity and its predictive role in immunosuppression after burns. Crit Care Med 27 (1999) 66-72
7. Barlow Y. T lymphocytes and immunosuppression in the burned patient. a review. Burns 20 (1994) 487-490
8. Molloy R.G., Nestor M., Collins K.H., Holzeimer R.G., Mannick J.A., and Rodrick M.L. The humoral immune response after thermal injury. an experimental model. Surgery 115 (1994) 341-348
9. O'Sullivan S.T., and O'Connor T.P. Immunosuppression following thermal injury. the pathogenesis of immunodysfunction. Br J Plast Surg 50 (1997) 615-623
10. Oberholzer A., Oberholzer C., and Moldawer L.L. Citokine signaling-regulation of the immune response in normal and critically ill states. Crit Care Med 28 (2000) 3-12
11. De Bandt J.P., Chollet-Martin S., Hernvann A., Lioret N., du Roure L.D., Lim S.K., et al. Cytokine response to burn injuries. J Trauma 36 (1994) 624-628
12. Struzyna J., Pojda Z., Braun B., Chomicka M., Sobiczewska E., and Wrembel J. Serum cytokine levels (IL-4, IL-6, IL-8, G-CSF, GM-CSF) in burned patients. Burns 21 (1995) 437-440
13. Bower R.H. Nutrition during critical illness and sepsis. New Horiz 1 (1993) 348-352
14. Enzi G., Casadei A., Sergi G., Chiarelli A., Zurlo F., and Mazzoleni F. Metabolic and hormonal effects of early nutritional supplementation after surgery in burn patients. Crit Care Med 18 (1990) 719-721
15. Dudrick P.S., and Souba W.W. Amino acids in surgical nutrition. principles and practice. Surg Clin North Am 71 (1991) 459-476
16. Mochizuki H., Trocki O., Dominioni L., Brackett K.A., Joffe S.N., and Alexander J.W. Mechanism of prevention of postburn hypermetabolism and catabolism by early enteral feeding. Ann Surg 200 (1984) 297-308
17. Saito H., Trocki O., Alexander J.W., Kopcha R., Heyd T., and Joffe S.N. The effect of nutrient administration on the nutritional state, catabolic hormone secretion and gut mucosal integrity after burn injury. JPEN 11 (1987) 1-7
18. Beale R.J., Bryg D.J., and Bihari D.J. Immunonutrition in the critically ill. a systematic review of clinical outcome. Crit Care Med 27 (1999) 2799-2805
19. Galban C., Montejo J.C., Mesejo A., Marco P., Celaya S., Sanchez-Segura J.M., et al. An immune-enhancing enteral diet reduces mortality rate and episodes of bacteremia in septic intensive care unit patients. Crit Care Med 28 (2000) 643-648
20. Kudsk K.A., Minard G., Croce M.A., Brown R.O., Lowrey T.S., Pritchard F.E., et al. A randomized trial of isonitrogenous enteral diets after severe trauma an immune-enhancing diet reduces septic complications. Ann Surg 224 (1996) 531-543
21. Evoy D., Lieberman M.D., Fahey III T.J., and Daly J.M. Immunonutrition. the role of arginine. Nutrition 14 (1998) 611-617
22. Yu Y.M., Sheridan R.L., Burke J.F., Chapman T.E., Tompkins R.G., and Young V.R. Kinetics of plasma arginine and leucine in pediatric burn patients. Am J Clin Nutr 64 (1996) 60-66
23. Cui X.L. Arginine-supplemented diet decreases expression of inflammatory cytokines and improves survival in burned rats. JPEN 24 (2000) 89-96
24. Saffle J.R., Wiebke G., Jennings K., Morris S.E., and Barton R.G. Randomized trial of immune-enhancing enteral nutrition in burn patients. J Trauma 42 (1997) 793-802
25. Bower R.H., Cerra F.B., Bershadsky B., Licari J.J., Hoyt D.B., Jensen G.L., et al. Early enteral administration of formula (Impact) supplemented with arginine, nucleotides, and fish oil in intensive care unit patients. results of multicenter, prospective, randomized, clinical trial. Crit Care Med 3 (1995) 436-449
26. Elsair J., Poey J., and Issad H. Effect of arginine chlorhydrate on nitrogen balance during the three days following routine surgery in man. Biomed Express 29 (1978) 312-317
27. Saito H., Trocki O., Wang S.L., Gonce S.J., Joffe S.N., and Alexander J.W. Metabolic and immune effects of dietary arginine supplementation after burn. Arch Surg 22 (1987) 784-789
28. Adjei A.A., Yamauchi K., Nakasone Y., Konishi M., and Yamamoto S. Arginine-supplemented diets inhibit endotoxin-induced bacterial translocation in mice. Nutrition 11 (1995) 371-374
29. Holland K.A., Gillespie R.W., Lewis N.M., and Kachman S.D. Estimating energy needs of pediatric patients with burns. J Burn Care Rehabil 16 (1995) 458-460
30. Oppenheim J.J., and Rosentreich D.L. In: Bloom B.R., and Davis J.R. (Eds). Lymphocyte transformation. utilization of automatic cell harvesters. In vitro methods in cell-mediated tumor immunity (1976), Academic Press, New York 73-85
31. Mediciǒn del cambio del estado nutricional (1983), World Health Organization; Ginebra, Ginebra
32. Chwals W.J., Fernandez M.E., Charles B.J., Schroeder L.A., and Turner C.S. Serum visceral protein levels reflect protein calorie repletion in neonates recovering from major surgery. J Pediatr Surg 27 (1992) 317-321
33. Anand K.J., Hansen D.D., and Hickey P.R. Hormonal-metabolic stress responses in neonates undergoing cardiac surgery. Anesthesiology 73 (1990) 661-670
34. Chwals W.J., Letton R.W., Jamie A., and Charles B. Stratification of injury severity using energy expenditure response in surgical infants. J Pediatr Surg 30 (1995) 1161-1164
35. Andel H., Kamolz L.P., Horauf K., and Zimpfer M. Nutrition and anabolic agents in burned patients. Burns 29 (1993) 592-595
36. Daly J.M., Reynolds J., Thom A., Kinsley L., and Dietrick-Gallager M. Immune and metabolic effects of arginine in surgical patient. Ann Surg 208 (1988) 512-523
37. Jeschke M.G., Herndon D.N., Ebener C., Barrow R.E., and Jauch K.W. Nutritional intervention high in vitamins, protein, amino acids, and omega-3 fatty acids improves protein metabolism during the hypermetabolic state after thermal injury. Arch Surg 136 (2001) 1301-1306
38. Alexander J.W. Nutritional pharmacology in surgical patients. Am J Surg 183 (2002) 349-352
39. Tsai H.J., Shang H.F., Yeh C.L., and Yeh S.L. Effects of arginine supplementation on antioxidant enzyme activity and macrophage response in burned mice. Burns 28 (2002) 258-263
40. Nieves Jr. C., and Langkamp-Henken B. Arginine and immunity. a unique perspective. Biomed Pharmacother 56 (2002) 471-482
41. Barbul A., Sisto D.A., Wasserkrug H.L., Yoshimura N.N., and Efron G. Metabolic and immune effects of arginine in post-injury hyperalimentation. J Trauma 21 (1981) 970-974
42. Cen Y., Luo X.S., and Liu X.X. Effect of L-arginine supplementation on partial-thickness burned patients. Chin J Reparat Reconstr Surg 13 (1999) 227-231
43. Yu Y.M., Ryan C.M., Castillo L., Lu X.M., Beaumier L., Tompkins R.G., and Young V.R. Arginine and ornithine kinetics in severely burned patients. increased rate of arginine disposal. Am J Physiol Endocrinol Metab 280 (2001) E509-E517
44. Kirk S.J., Regan M.C., Wasserkrug H.L., Sodeyama M., and Barbul A. Arginine enhances T-cell responses in athymic nude mice. JPEN 16 (1992) 429-432
45. Gianotti L., Alexander J.W., Pyles T., and Fukushima R. Arginine-supplemented diets improve survival in gut-derived sepsis and peritonitis by modulating bacterial clearance. The role of nitric oxide. Ann Surg 217 (1993) 644-654
46. Yan H., Peng X., Wang P., Huang Y.S., and Wang S.L. Influence of the enteral feeding of levorotatory arginine on severely burned patients during shock stage. Zhonghua Shao Shang Za Zhi 21 (2005) 251-254
47. Wu J.Z., Ogle C.K., Mao J.X., Szczur K., Fischer J.E., and Ogle J.D. The increased potential for the production of inflammatory cytokines by Kupffer cells and splenic macrophages eight days after thermal injury. Inflammation 19 (1995) 529-541