An animal model of chronic inflammatory pain: Pharmacological and temporal differentiation from acute models

European Journal of Pain

Volumn 10, Issue 6, 2006, Pages 537-

  Wilson, Alex W ^a   Medhurst, Stephen J ^a   Dixon, Claire I ^a   Bontoft, Nick C ^a   Winyard, Lisa A ^a   Brackenborough, Kim T ^a   Alba, Jorge De ^a   Clarke, Christopher J ^a   Gunthorpe, Martin J ^a   Hicks, Gareth A ^a   Bountra, Chas ^a   McQueen, Daniel S ^b   Chessell, Iain P ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Chronic inflammation pain; Hypersensitivity; iNOS inhibitor; Joint; NR2B antagonist

Indexed keywords

4 BENZYL ALPHA (4 HYDROXYPHENYL) BETA METHYL 1 PIPERIDINEPROPANOL; ADJUVANT; DEXAMETHASONE; ETORICOXIB; IBUPROFEN; INDUCIBLE NITRIC OXIDE SYNTHASE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NITRIC OXIDE SYNTHASE INHIBITOR; ROFECOXIB; S [2 (1 IMINOETHYLAMINO)ETHYL]HOMOCYSTEINE;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC ARTHRITIS; CHRONIC DISEASE; CHRONIC INFLAMMATORY PAIN; CHRONIC PAIN; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; HYPERALGESIA; INFLAMMATION; INJECTION; JOINT CAVITY; KNEE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; VALIDATION STUDY;

EID: 33745346911     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1016/j.ejpain.2005.08.003     Document Type: Article

References (35)

1. Arthritis Research Campaign, 2004. Available from: http://www.arc.org.uk.
2. Bileviciute I., Lundberg T., Ekblom A., and Theodorsson E. Bilateral changes of substance P-, neurokinin A-, clacitonin gene-related peptide- and neuropeptide Y-like immunoreactivity in rat knee joint synovial fluid during acute monoarthritis. Neurosci Lett 153 (1993) 37-40
3. Bolay H., and Moskowitz M.A. Mechanisms of pain modulation in chronic syndromes. Neurology 59 (2002) S2-S7
4. Boyce C., Wyatt A., Webb J.K., O'Donnell R., Mason G., Rigby M., et al. Selective NMDA NR2B antagonists induce antinociception without motor dysfunction; correlation with restricted localisation of NR2B subunit in dorsal horn. Neuropharmacology 38 (1999) 611-623
5. Brack A., Rittner H.L., Machelska H., Shaqura M., Mousa S.A., Labuz D., et al. Endogenous peripheral antinociception in early inflammation is not limited by the number of opioid-containing leukocytes but by opioid receptor expression. Pain 108 (2004) 67-75
6. Chaplan S.R., Bach F.W., Pogrel J.W., Chung J.M., and Yaksh T.L. Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Meth 53 (1994) 55-63
7. Chazot P.L. CP-101606 Pfizer Inc. Curr Opin Investig Drugs 1 (2000) 370-374
8. Claiborne C.F., McCauley J.A., Libby B.E., Curtis N.R., Diggle H.J., Kulagowski J.J., et al. Orally efficacious NR2B-selective NMDA receptor antagonists. Bioorg Med Chem Lett 13 (2003) 697-700
9. Clayton N.M., Oakley I., Thompson S., Wheeldon A., Sargent B., and Bountra C. Validation of the dual channel weight averager as an instrument for the measurement of clinically relevant pain. Br J Pharmacol 120 (1997) 219P (Abstract)
10. Colpaert F.C. Evidence that adjuvant arthritis in the rat is associated with chronic pain. Pain 28 (1987) 210-222
11. Cuzzocrea S., Chatterjee P.K., Mazzon E., McDonald M.C., Dugo L., Di Paola R., et al. Beneficial effects of GW274150, a novel, potent and selective inhibitor of iNOS activity, in a rodent model of collagen-induced arthritis. Eur J Pharmacol 453 (2002) 119-129
12. Donaldson L.F., Sechkl J.R., and McQueen D.S. A discrete adjuvant-induced monoarthritis in the rat: effects of adjuvant dose. J Neurosci Meth 49 (1993) 5-10
13. Heidinger V., Manzerra P., Wang X.W., Strasser U., Yu S.-P., Choi D.W., et al. Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons. J Neurosci 22 (2002) 5452-5461
14. LaBuda C.J., and Fuchs P.N. A comparison of chronic aspartame exposure to aspirin on inflammation, hyperalgesia and open field activity following carrageenan-induced monoarthritis. Life Sci 69 (2001) 443-454
15. Loftis J.M., and Janowsky A. The N-methyl-d-aspartate receptor subunit NR2B: localisation, functional properties, regulation, and clinical implications. Pharmacol Ther 97 (2003) 55-85
16. Machelska H., Mousa S.A., Brack A., Schopohl J.K., Rittner H.L., Schafer M., et al. Opioid control of inflammatory pain regulated by intercellular adhesion molecule-1. J Neurosci 22 (2002) 5588-5596
17. Mapp P.I., Terenghi G., Walsh D.A., Chen S.T., Cruwys S.C., Garrett N., et al. Monoarthritis in the rat knee induces bilateral and time-dependent changes in substance P and calcitonin gene related peptide immunoreactivity in the spinal cord. Neuroscience 57 (1993) 1091-1096
18. Mardini I.A., and FitzGerald G.A. Selective inhibitors of cyclooxygenase-2: a growing class of anti-inflammatory drugs. Mol Intervent (2001) 130-138
19. Miki K., Zhou Q.-Q., Guan G.Y., Dubner T.R., and Ren K. Changes in gene expression and neuronal phenotype in brain stem pain modulatory circuitry after inflammation. J Neurophysiol 87 (2002) 750-760
20. Millan M.J. Multiple opioid systems and pain. Pain 27 (1986) 303-347
21. Nagakura Y., Okada M., Kohara A., Kiso T., Toya T., Iwai A., et al. Allodynia and hyperalgesia in adjuvant-induced arthritic rats: time course of progression and efficacy of analgesics. JPET 306 (2003) 490-497
22. Nikam S.S., and Meltzer L.T. NR2B selective NMDA receptor antagonists. Curr Pharmaceut Design 8 (2002) 845-855
23. Pearson C.M., and Wood F.D. Studies of polyarthritis and other lesions induced in rats by injection of mycobacterial adjuvant. I. General clinical and pathological characteristics and some modifying factors. Arth Rheum 2 (1959) 440-459
24. Pourpak Z., Ahmadiani A., and Alebouyeh M. Involvement of interleukin-1β in systemic morphine effects on paw oedema in a mouse model of acute inflammation. Scand J Immunol 59 (2004) 273-277
25. Rainsford K.D. Adjuvant polyarthritis in rats: is this a satisfactory model for screening anti-arthritic drugs?. Agents & Actions 12 (1982) 452-458
26. Randall L.O., and Selitto J.J. A method for measurement of analgesic activity on inflamed tissue. Arch Int de Pharmacodyn et de Therapie 111 (1957) 409-419
27. Rubens-Duval A., Villiaumey J., and Kaplan G. Attempts at experimental reproduction of rheumatic polyarthritis. Pathologie et Biologie 14 (1996) 1084-1100
28. Sanjue H., and Jun Z. Sympathetic facilitation of sustained discharges of polymodal nociceptors. Pain 38 (1989) 85-90
29. Schaible H.-G., and Schmidt R.F. Time course of mechanosensitivtiy changes in articular afferents during a developing experimental arthritis. J Neurophysiol 60 (1988) 2180-2195
30. Stein C., Millan M.J., and Herz A. Unilateral inflammation of the hindpaw in rats as a model of prolonged noxious stimulation: alterations in behavior and nociceptive thresholds. Pharm Biochem Behav 31 (1988) 445-451
31. Stein C., Schäfer M., and Machelska H. Attacking pain at it's source: a new perspective on opioids. Nat Med 9 (2003) 1003-1008
32. Taniguchi K., Shinjo K., Mizutani M., Shimada K., Ishikawa T., Menniti F.S., et al. Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist. Br J Pharmacol 122 (1997) 809-812
33. Wall P.D. Introduction. In: Wall P.D. (Ed). Textbook of pain (1984), Chruchill Livingstone, New York 1-16
34. Wu J., Lin Q., Feng Y., and Willis W.D. Contribution of inducible and neuronal nitric oxide synthesis to allodynia of rats following intradermal injection of capsaicin. Soc Neurosci Abstr 23 (1997) 6976
35. Wu J., Lin Q., Willis W.D., and Westlund K.N. Changes in nitric oxide synthase isoforms in the spinal cord or rat following induction of chronic arthritis. Exp Brain Res 118 (1998) 457-465