Chemical synthesis of 2′-deoxyguanosine-C8 adducts with heterocyclic amines: An application to synthesis of oligonucleotides site-specifically adducted with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Chemical Research in Toxicology

Volumn 19, Issue 6, 2006, Pages 770-778

  Takamura Enya, Takeji ^a   Ishikawa, Satoko ^b   Mochizuki, Masataka ^b   Wakabayashi, Keiji ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; 2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; 2 AMINO 6 METHYLDIPYRIDO[1,2 A:3',2' D]IMIDAZOLE; 3 AMINO 1,4 DIMETHYL 5H PYRIDO[4,3 B]INDOLE; 9,9 DIMETHYL 4,5 BIS(DIPHENYLPHOSPHINO)XANTHENE; AMINE; BIPHENYL DERIVATIVE; CARCINOGEN; CESIUM; CESIUM CARBONATE; DEOXYGUANOSINE; DIMETHYL SULFOXIDE; HETEROCYCLIC AMINE; IMIDAZOLE DERIVATIVE; MUTAGENIC AGENT; OLIGONUCLEOTIDE; PALLADIUM COMPLEX; PHOSPHINE DERIVATIVE; PHOSPHORAMIDOUS ACID DERIVATIVE; SOLVENT; TRIS(DIBENZYLIDENEACETONE)DIPALLADIUM; UNCLASSIFIED DRUG; XANTHENE DERIVATIVE;

AMINATION; ARTICLE; ARYLATION; BUCHWALD HARTWIG REACTION; CHEMICAL REACTION; CROSS COUPLING REACTION; DEPROTECTION REACTION; DNA SYNTHESIS; REACTION ANALYSIS; REACTION TIME; SYNTHESIS; TEMPERATURE DEPENDENCE;

AMINATION; AMINES; BROMINE COMPOUNDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANINE NUCLEOTIDES; HETEROCYCLIC COMPOUNDS; IMIDAZOLES; MOLECULAR STRUCTURE; OLIGONUCLEOTIDES; ORGANOPHOSPHORUS COMPOUNDS; SOLVENTS; SPECTRUM ANALYSIS;

EID: 33745295131     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx050296s     Document Type: Article

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