Attenuation of neutrophil infiltration and proinflammatory cytokines by Cissus quadrangularis: A possible prevention against gastric ulcerogenesis

Journal of Herbal Pharmacotherapy

Volumn 5, Issue 3, 2005, Pages 33-42

  Jainu, Mallika ^a   Devi, Chennam Srinivasulu Shyamala ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Aspirin; Cissus quadrangularis; Lipid peroxidation; Neutrophil infiltration; TNF

Indexed keywords

ACETYLSALICYLIC ACID; ANTIOXIDANT; CARBONYL REDUCTASE; CISSUS QUADRANGULARIS EXTRACT; CYTOKINE; MALONALDEHYDE; PLANT EXTRACT; RANITIDINE; REACTIVE OXYGEN METABOLITE; THIOL DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; URIC ACID; XANTHINE OXIDASE;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CISSUS; CISSUS QUADRANGULARIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; IMMUNOMODULATION; LIPID PEROXIDATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PLANT STEM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONTENT; RAT; STOMACH MUCOSA; STOMACH PROTECTION; STOMACH ULCER; ULCER HEALING; ULCEROGENESIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-ULCER AGENTS; ASPIRIN; CISSUS; CYTOKINES; DISEASE MODELS, ANIMAL; GASTRIC MUCOSA; MALE; NEUTROPHIL INFILTRATION; NEUTROPHILS; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; PROTECTIVE AGENTS; RATS; RATS, WISTAR; STOMACH ULCER;

EID: 33745289772     PISSN: 15228940     EISSN: 15229106     Source Type: Journal    
DOI: 10.1300/J157v05n03_04     Document Type: Article

References (35)

1. Nishida T, Tsuji M, Tsuji S. Are COX-2 inhibitors truly able to prevent NSAID-associated ulcer? Nippon Rhinsho 2004;62:561-65.
2. Villegas I, Martin MJ, La Casa C. Effects of meloxicam on oxygen radical generation in rat gastric mucosa. Inflamm Res 2000;49:361-66.
3. Beck PL, Xavier R, Lu N. Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice. Gastroenterology 2000;119:699-705.
4. Liu ESL, Cho CH. Relationship between ethanol-induced gastritis and gastric ulcer formation in rats. Digestion 2000;62:232-39.
5. Glaven GB, Szabo S. Experimental gastric mucosal injury: Laboratory models reveal mechanisms of pathogenesis and new therapeutic strategies. Faseb J 1992; 6:825-30.
6. Konturek PC, Brozozowski T, Konturek SJ, Kwiecien S, Dembinski A, Hahn EG. Influence of bacterial lipopolysaccharide on healing of chronic experimental ulcer in rat. Scand J Gastroenterol 2001;36:1239-47.
7. Arakawa T, Higuchi K, Takashi F. Prostaglandins in the stomach: An update. J Clin Gastroenterol 1998;27:S1-S11.
8. Warrier PK, Nambiar VPK, Raman Kutty C: Indian Medicinal plants, Vol 2, Orient Longman, Chennai, India. 1993:112-115.
9. Shirwaikar A, Khan S, Malini S. Antiosteoporotic effect of ethanolic extract of Cissus quadrangularis L. on ovariectomized rat. J Ethnopharmacol 2003;89:245-50.
10. Subbu VSV. Mechanism of action of Vitis glucoside on myocardial tissue. Ind J Med Sci 1970;25:400-403.
11. Nadkarni AK. Cissus quadrangularis. In: Indian Materia Medica, 3rd Ed. Popular Book Depot, Bombay, India. 1954:1284-86.
12. Chidambara Murthy KN, Vanitha A, Mahadeva Swamy M, Ravishankar GA. Antioxidant and antimicrobial activity of Cissus quadranqularis Linn. J Med Food 2003;6:99-105.
13. Mallika Jainu, Shyamala Devi CS. Potent antiulcerogenic activity of methanol extract of Cissus quadrangularis by antioxidative mechanism. J Clin Biochem Nutr 2003;34:43-7.
14. Mallika Jainu, Shyamala Devi CS. Effect of Cissus quadrangularis on gastric mucosal defensive factors in experimentally induced gastric ulcer - a comparative study with sucralfate. J Med Food 2004;7:372-76.
15. Szabo S, Gallagher GT, Horner SJ, Brozowski T, Trier JS. Role of the adrenal cortex in gastric mucosal protection by prostaglandins, sulphydryls, and cimetidine in the rat. Gastroenterology 1983;85:1384-90.
16. Okhawa H, Ohishi N, Yagi K. Assay for lipid peroxide in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-57.
17. Caraway WT. In: Standard methods in Clinical Chemistry, Selingston (Ed.), Academic Press, New York. 1963:239-47.
18. Levine RL, Garland D, Oliver CN, Amici A, Climent I, Laoz AG, Ahn BW, Shaltiel S, Stadtman ER. Methods Enzymol 1990;186:464-78.
19. Klein RA. The detection of oxidation in liposomal preparations. Biochem Biophys Acta 1983;210:486-89.
20. Hashimoto S. New spectrophotometric assay method of xanthine oxidase in crude tissue homogenate. Anal Biochem 1979;95:351-58.
21. Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984;87:1344-50.
22. Lowry OH, Rosebrough NH, Farr AL, Randal RI. Protein measurement with Folin Phenol reagent. J Biol Chem 1951;193:265-75.
23. Misra HP, Fridovich I. The role of superoxide anion in the auto-oxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 1972;247:3170-75.
24. Sinha AK. Colorimetric assay of catalase. Anal Biochem 1972;47:389-94.
25. Rotruck JT, Pope AL, Ganther H, Awanson AB, Hafeman DG, Hoeckstra WG. Selenium biochemical role as a component of glutathione peroxidase. Science 1973; 179:588-90.
26. Garg CP, Cho CH, Ogle CW. The role of gastric mucosal sulphydryls in the ulcer-protecting effects of sulphasalazine. J Pharm Pharmacol 1991;43:733-34.
27. 2 derived free radicals in chronic gastric lesion induced by acetic acid in rat. Gen Pharmacol 1996;27:545-50.
28. Yoshida N, Yoshikawa T, Nakamura Y. Role of neutrophil-endothelial cell interaction in gastric mucosal injury induced by aspirin. J Clin Gastroenterol 1995; 21:S73-S77.
29. Yihuai Gao, Shufeng Zhou, Jianbo wen, Min Huang, Anlong Xu. Mechanism of the antiulcerogenic effect of Ganoderma lucidum polysaccharides on indomethacin induced lesions in the rat. Life Science 2002;72:731-45.
30. Galunsaka B, Marazova K, Yankova T, Popov A, Frangov P, Krushkov I, Di Massa A. Effects of paracetamol and propacetamol on gastric mucosal damage and gastric lipid peroxidation caused by acetyl salicylic acid in rats. Pharmacol Res 2002;467:141-48.
31. Casini A, Ceni E, Salano R, Biondi P, Parola M, Call A, Foschi M. Neutrophil derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human stellate cells: Role of nitric oxide. Hepatology 1997;25:361-67.
32. Stèlmaszynska T, Kukovez E, Egger G, Shaur RJ. Possible involvement of myeloperoxidase in lipid peroxidation. Intern J Biochem 1992;24:121-28.
33. Fridovich I. Biological effects of the superoxide radical. Arch Biochem Biophys 1986;247:1-11.
34. Shaw S, Herbert V, Colman N, Jayatilleke E. Effect of ethanol-generated free radicals on gastric intrinsic factor and glutathione. Alcohol 1990;7:153-57.
35. Szabo S. Mechanism of mucosal injury in the stomach and duodenum: Time sequence analysis of morphologic, functional, biochemical and histochemical studies. Scand J Gastroenterol 1987;127:121-28.