Deletion analysis of oligomycin PKS genes (olmA) in Streptomyces avermitilis

Chinese Science Bulletin

Volumn 49, Issue 4, 2004, Pages 350-354

  Zhang, Xiaolin ^a   Chen, Zhi ^a   Zhao, Jinlei ^a   Song, Yuan ^a   Wen, Ying ^a   Li, Jilun ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Avermectin; Oligomycin; olmA gene cluster deletion; Streptomyces avermitilis

Indexed keywords

STREPTOMYCES; STREPTOMYCES AVERMITILIS;

EID: 33745289155     PISSN: 10016538     EISSN: 18619541     Source Type: Journal    
DOI: 10.1360/03WC0469     Document Type: Article

References (21)

1. Burg, R. W., Miller, B. M., Baker, E. E. et al., Avermectins, new family of potent anthelmintic agents: Producing organisms and fermentation, Antimicrob Agents Chemother, 1979, 15: 361-367.
2. Egerton, J. R., Ostlind, D. A., Blair, L. S. et al., Avermectins, new family of potent anthelmintic agents: Efficacy of the B1a component, Antimicrob Agents Chemother, 1979, 15: 372-378.
3. Pinna, L. A., Lorini, M., Moret, V. et al., Effect of oligomycin and succinate on mitochondrial metabolism of adenine nucleotides, Biochim. Biophys. Acta, 1967, 143: 18-25.
4. Ikeda, H., Omura, S., Genetic aspects of the selective production of useful components in the avermectin producer Streptomyces avermitilis, Actinomycetol, 1993, 7: 133-144.
5. Ikeda, H., Omura, S., Avermectin biosynthesis, Chem. Rev., 1997, 97: 2591-2609.
6. MacNeil, T., Gewain, K. M., MacNeil, D. J., Deletion analysis of the avermectin biosynthetic genes of Streptomyces avermitilis by gene cluster displacement, J. Bacteriol, 1993, 175: 2552-2563.
7. Ikeda, H., Takada, Y., Pang, C.-H. et al., Transposon mutagenesis by Tn4560 and applications with avermectin-producing Streptomyces avermitilis, J. Bacteriol., 1993, 175: 2077-2082.
8. Ikeda, H., Nonomiya, T., Usami, M. et al., Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis, Proc. Natl. Acad. Sci. USA, 1999, 96: 9509-9514.
9. Ikeda, U., Ishikaw, J., Hanamoto, A. et al., Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis, Nature Biotechnol., 2003, 21: 526-531.
10. Omura, S., Ikeda, H., Ishikawa, J., Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites, Proc. Natl. Acad. Sci. USA, 2001, 98: 12215-12220
11. Chen, Z., Wen, Y., Song, Y. et al., Effect of gene deletion of aveD on avermectins production in Streptomyces avermitilis, Acta Microbiol. Sinica, 2002, 42(5): 534-538.
12. Bierman, M., Logan, R., O'Brien, K. et al., Plasmid cloning vectors for the conjugal transfer of DNA from Esherichia coli to Streptomyces spp, Gene, 1992, 116: 43-49.
13. Sambrook, J., Fritsch, E. F., Maniatis, T., Molecular cloning, A Laboratory Manual, 2nd ed., New York: Cold Spring Harbor Laboratory Press, 1989.
14. MacNeil, D. J., Klapko, L. M., Transformation of Streptomyces avermitilis by plasmid DNA, J. Ind. Microbiol., 1987, 2: 209-218.
15. Ikeda, H., Kotaki, H., Tanaka, H. et al., Involvement of glucose catabolism in avermectin production by Streptomyces avermitilis, Antimicrob Agents Chemother, 1988, 32(2): 282-284.
16. Hanahan, D., Studies on transformation of Escherichia coli with plasmids, J. Mol. Biol., 1983, 166: 557.
17. Janssen, G. R., Bibb, M. J., Derivatives of pUC18 that have BglII sites flanking a modified multiple cloning site and that retain the ability to identify recombinant clones by visual screening of Escherichia coli colonies, Gene, 1993, 124: 133.
18. Hopwood, D. A., Bibb, M. J., Chater, K. F. et al., Genetic manipulation of Streptomyces, A Laboratory Manual, Norwich: John Innes Foundation, 1985.
19. Song, Y., Cao, G. M., Chen, Z. et al., Selection of high avermectins producing strain and identification of avermectin B1, Chinese Journal of Biotechnology, 2000, 16 (1): 31-35.
20. Ikeda, H., Pang, C. H., Endo, H. et al., Construction of a single component producer from the wild type avermectin producer Streptomyces avermitilis, J. Antibiot., 1995, 48(6): 532-534.
21. Kieser, T., Factors affecting the isolation of cccDNA from Streptomyces lividans and Escherichia coli, Plasmid, 1984, 12: 19-36.