Trait components provide tools to dissect the genetic susceptibility of migraine

American Journal of Human Genetics

Volumn 79, Issue 1, 2006, Pages 85-99

  Anttila, V ^a   Kallela, M ^b   Oswell, G ^a,e   Kaunisto, M A ^a   Nyholt, D R ^f   Hamalainen E ^a   Havanka, H ^g   Ilmavirta, M ^h   Terwilliger, J ^a,i   Sobel, E ^e   Peltonen, L ^a,c,j   Kaprio, J ^a,c   Farkkila M ^b   Wessman, M ^a,d   Palotie, Aarno ^a,j,k  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^d FOLKHÄLSAN RESEARCH CENTER   (Finland)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^g Lansi Pohja Central Hospital   (Finland)

^h JYVÄSKYLÄ CENTRAL HOSPITAL   (Finland)

ⁱ Columbia University ^*  (United States)

^j BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^k Finnish Genome Center   (Finland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 10Q; CHROMOSOME 12Q; CHROMOSOME 15Q; CHROMOSOME 18Q; CHROMOSOME 4Q; EXERCISE; FEMALE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MIGRAINE; ONSET AGE; PHENOTYPE; PHONOPHOBIA; PRIORITY JOURNAL;

EID: 33745233339     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/504814     Document Type: Article

References (50)

1. Russell MB, Rasmussen BK, Thorvaldsen P, Olesen J (1995) Prevalence and sex-ratio of the subtypes of migraine. Int J Epidemiol 24:612-618
2. Honkasalo ML, Kaprio J, Winter T, Heikkila K, Sillanpaa M, Koskenvuo M (1995) Migraine and concomitant symptoms among 8167 adult twin pairs. Headache 35:70-78
3. Larsson B, Bille B, Pederson NL (1995) Genetic influence in headaches: a Swedish twin study. Headache 35:513-519
4. Gervil M, Ulrich V, Kyvik KO, Olesen J, Russell MB (1999) Migraine without aura: a population-based twin study. Ann Neurol 46:606-611
5. Ulrich V, Gervil M, Kyvik KO, Diesen J, Russell MB (1999) Evidence of a genetic factor in migraine with aura: a population-based Danish twin study. Ann Neurol 45:242-246
6. Russell MB, Iselius L, Olesen J (1996) Migraine without aura and migraine with aura are inherited disorders. Cephalalgia 16:305-309
7. Wessman M, Kallela M, Kaunisto MA, Marttila P, Sobel E, Hartiala J, Oswell G, Leal SM, Papp JC, Hamalainen E, Broas P, Joslyn G, Hovatta I, Hiekkalinna T, Kaprio J, Ott J, Cantor RM, Zwart JA, Ilmavirta M, Havanka H, Farkkila M, Peltonen L, Palotie A (2002) A susceptibility locus for migraine with aura, on chromosome 4q24. Am J Hum Genet 70:652-662
8. Cader ZM, Noble-Topham S, Dyment DA, Cherny SS, Brown JD, Rice GP, Ebers GC (2003) Significant linkage to migraine with aura on chromosome 11q24. Hum Mol Genet 12:2511-2517
9. Russo L, Mariotti P, Sangiorgi E, Giordano T, Ricci I, Lupi F, Chiera R, Guzzetta F, Neri G, Gurrieri F (2005) A new susceptibility locus for migraine with aura in the 15q11-q13 genomic region containing three GABA-A receptor genes. Am J Hum Genet 76:327-333
10. Lea RA, Nyholt DR, Curtain RP, Ovcaric M, Sciascia R, Bellis C, Macmillan J, Quinlan S, Gibson RA, McCarthy LC, Riley JH, Smithies YJ, Kinrade S, Griffiths LR (2005) A genome-wide scan provides evidence for loci influencing a severe heritable form of common migraine. Neurogenetics 6:67-72
11. Nyholt DR, Morley KI, Ferreira MA, Medland SE, Boomsma DI, Heath AC, Merikangas KR, Montgomery GW, Martin NG (2005) Genomewide significant linkage to migrainous headache on chromosome 5q21. Am J Hum Genet 77:500-512
12. Nyholt DR, Curtain RP, Griffiths LR (2000) Familial typical migraine: significant linkage and localization of a gene to Xq24-28. Hum Genet 107:18-23
13. Soragna D, Vettori A, Carraro G, Marchioni E, Vazza G, Bellini S, Tupler R, Savoldi F, Mostacciuolo ML (2003) A locus for migraine without aura maps on chromosome 14q21.2-q22.3. Am J Hum Genet 72:161-167
14. Carlsson A, Forsgren L, Nylander PO, Hellman U, Forsman-Semb K, Holmgren G, Holmberg D, Holmberg M (2002) Identification of a susceptibility locus for migraine with and without aura on 6p12.2-p21.1. Neurology 59:1804-1807
15. Björnsson A, Gudmundsson G, Gudfinnsson E, Hrafnsdottir M, Benedikz J, Skuladottir S, Kristjansson K, Frigge ML, Kong A, Stefansson K, Gulcher JR (2003) Localization of a gene for migraine without aura to chromosome 4q21. Am J Hum Genet 73:986-993
16. + pump α2 subunit associated with familial hemiplegic migraine type 2. Nat Genet 33:192-196
17. Dichgans M, Freilinger T, Eckstein G, Babini E, Lorenz-Depiereux B, Biskup S, Ferrari MD, Herzog J, van den Maagdenberg AM, Pusch M, Strom TM (2005) Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. Lancet 366:371-377
18. 2+ channel gene CACNL1A4. Cell 87:543-552
19. International Headache Society (1988) Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Headache Classification Committee of the International Headache Society. Cephalalgia 8:1-96
20. Headache Classification Subcommittee of the International Headache Society (2004) The International Classification of Headache Disorders: 2nd edition. Cephalalgia Suppl 1 24:9-160
21. Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nunez G, Cho JH (2001) A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411:603-606
22. Edwards AO, Ritter R 3rd, Abel KJ, Manning A, Panhuysen C, Farrer LA (2005) Complement factor H polymorphism and age-related macular degeneration. Science 308:421-424
23. Bottini N, Musumeci L, Alonso A, Rahmouni S, Nika K, Rostamkhani M, MacMurray J, Meloni GF, Lucarelli P, Pellecchia M, Eisenbarth GS, Comings D, Mustelin T (2004) A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 36:337-338
24. Bouzigon E, Dizier MH, Krahenbuhl C, Lemainque A, Annesi-Maesano I, Betard C, Bousquet J, Charpin D, Gormand F, Guilloud-Bataille M, Just J, Le Moual N, Maccario J, Matran R, Neukirch F, Oryszczyn MP, Paty E, Pin I, Rosenberg-Bourgin M, Vervloet D, Kauffmann F, Lathrop M, Demenais F (2004) Clustering patterns of LOD scores for asthma-related phenotypes revealed by a genome-wide screen in 295 French EGEA families. Hum Mol Genet 13:3103-3113
25. Hamet P, Merlo E, Seda O, Broeckel U, Tremblay J, Kaldunski M, Gaudet D, Bouchard G, Deslauriers B, Gagnon F, Antoniol G, Pausova Z, Labuda M, Jomphe M, Gossard F, Tremblay G, Kirova R, Tonellato P, Orlov SN, Pintos J, Platko J, Hudson TJ, Rioux JD, Kotchen TA, Cowley AW Jr (2005) Quantitative founder-effect analysis of French Canadian families identifies specific loci contributing to metabolic phenotypes of hypertension. Am J Hum Genet 76:815-832
26. Alarcon M, Cantor RM, Liu J, Gilliam TC, Geschwind DH (2002) Evidence for a language quantitative trait locus on chromosome 7q in multiplex autism families. Am J Hum Genet 70:60-71
27. Pajukanta P, Nuotio I, Terwilliger JD, Porkka KV, Ylitalo K, Pihlajamaki J, Suomalainen AJ, Syvanen AC, Lehtimaki T, Viikari JS, Laakso M, Taskinen MR, Ehnholm C, Peltonen L (1998) Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23. Nat Genet 18:369-373
28. Paunio T, Tuulio-Henriksson A, Hiekkalinna T, Perola M, Varilo T, Partonen T, Cannon TD, Lonnqvist J, Peltonen L (2004) Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q. Hum Mol Genet 13:1693-1702
29. Kallela M, Wessman M, Färkkilä M (2001) Validation of a migraine specific questionnaire for use in family studies. Eur J Neurol 8:61-66
30. Hovatta I, Kallela M, Farkkila M, Peltonen L (1994) Familial migraine: exclusion of the susceptibility gene from the reported locus of familial hemiplegic migraine on 19p. Genomics 23:707-709
31. Göring HH, Terwilliger JD (2000) Linkage analysis in the presence of errors III: marker loci and their map as nuisance parameters. Am J Hum Genet 66:1298-1309
32. Sobel E, Lange K (1996) Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet 58:1323-1337
33. Lathrop GM, Lalouel JM (1984) Easy calculations of lod scores and genetic risks on small computers. Am J Hum Genet 36:460-465
34. Ott J (1983) Linkage analysis and family classification under heterogeneity. Ann Hum Genet 47:311-320
35. Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES (1996) Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 58:1347-1363
36. Kidd KK, Ott J (1984) Power and sample-size in linkage studies. Cytogenet Cell Genet 37:510-511
37. Nyholt DR (2004) A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74:765-769
38. Li J, Ji L (2005) Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity 95:221-227
39. Cheverud JM (2001) A simple correction for multiple comparisons in interval mapping genome scans. Heredity 87:52-58
40. Ott J (1989) Computer-simulation methods in human linkage analysis. PNAS 86:4175-4178
41. Blau JN (1995) Migraine with aura and migraine without aura are not different entities. Cephalalgia 15:186-190
42. Russell MB, Ulrich V, Gervil M, Olesen J (2002) Migraine without aura and migraine with aura are distinct disorders: a population-based twin survey. Headache 42:332-336
43. Gottesman II, Gould TD (2003) The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiat 160:636-645
44. Shoulders CC, Jones EL, Naoumova RP (2004) Genetics of familial combined hyperlipidemia and risk of coronary heart disease. Hum Mol Genet 13:R149-R160
45. Laitinen T, Daly MJ, Rioux JD, Kauppi P, Laprise C, Petays T, Green T, Cargill M, Haahtela T, Lander ES, Laitinen LA, Hudson TJ, Kere J (2001) A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population. Nat Genet 28:87-91
46. Egan MF, Goldberg TE (2003) Intermediate cognitive phenotypes associated with schizophrenia. Methods Mol Med 77:163-197
47. Ashina M, Bendtsen L, Jensen R, Schifter S, Jansen-Olesen I, Olesen J (2000) Plasma levels of calcitonin gene-related peptide in chronic tension-type headache. Neurology 55:1335-1340
48. Owen MJ, Craddock N, O'Donovan MC (2005) Schizophrenia: genes at last? Trends Genet 21:518-525
49. Nyholt DR, Gillespie NG, Heath AC, Merikangas KR, Duffy DL, Martin NG (2004) Latent class and genetic analysis does not support migraine with aura and migraine without aura as separate entities. Genet Epidemiol 26:231-244
50. Rindskopf D, Rindskopf W (1986) The value of latent class analysis in medical diagnosis. Stat Med 5:21-27