메뉴 건너뛰기




Volumn 6, Issue 1-2, 2006, Pages 1-13

Simulation-based validation of the p53 transcriptional activity with hybrid functional Petri net

Author keywords

Biological pathway; Hybrid functional Petri net; p53; Simulation

Indexed keywords

PROTEIN MDM2; PROTEIN P19ARF; PROTEIN P53; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 33745213569     PISSN: 13866338     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (28)

References (25)
  • 2
    • 0027459198 scopus 로고
    • mdm2 expression is induced by wild type p53 activity
    • Barak, Y., Juven, T., Haffner, R. and Oren, M. (1993). mdm2 expression is induced by wild type p53 activity. EMBO J. 12, 461-468.
    • (1993) EMBO J. , vol.12 , pp. 461-468
    • Barak, Y.1    Juven, T.2    Haffner, R.3    Oren, M.4
  • 3
    • 2642527148 scopus 로고    scopus 로고
    • Genomic Object Net: II. Modelling biopathways by hybrid functional Petri net with extension
    • Doi, A., Nagasaki, M., Fujita, S., Matsuno, H. and Miyano, S. (2003). Genomic Object Net: II. Modelling biopathways by hybrid functional Petri net with extension. Appl. Bioinformatics 2, 185-188.
    • (2003) Appl. Bioinformatics , vol.2 , pp. 185-188
    • Doi, A.1    Nagasaki, M.2    Fujita, S.3    Matsuno, H.4    Miyano, S.5
  • 4
    • 10044242838 scopus 로고    scopus 로고
    • Constructing biological pathway models with hybrid functional Petri net
    • Doi, A., Fujita, S., Matsuno, H., Nagasaki, M. and Miyano, S. (2004). Constructing biological pathway models with hybrid functional Petri net. In Silico Biol. 4, 0023.
    • (2004) In Silico Biol. , vol.4 , pp. 0023
    • Doi, A.1    Fujita, S.2    Matsuno, H.3    Nagasaki, M.4    Miyano, S.5
  • 5
    • 0031987277 scopus 로고    scopus 로고
    • Regulation of p53 downstream genes
    • el-Deiry W. S. (1998). Regulation of p53 downstream genes. Semin. Cancer Biol. 8, 345-357.
    • (1998) Semin. Cancer Biol. , vol.8 , pp. 345-357
    • el-Deiry, W.S.1
  • 6
    • 10444281590 scopus 로고    scopus 로고
    • Modeling and simulation of fission yeast cell cycle on hybrid functional Petri net
    • E87-A
    • Fujita, S., Matsui, M., Matsuno, H. and Miyano, S. (2004). Modeling and simulation of fission yeast cell cycle on hybrid functional Petri net. IEICE Trans. Fundamentals E87-A, 2919-2928.
    • (2004) IEICE Trans. Fundamentals , pp. 2919-2928
    • Fujita, S.1    Matsui, M.2    Matsuno, H.3    Miyano, S.4
  • 7
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
    • Honda, R., Tanaka, H. and Yasuda, H. (1997). Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett. 420, 25-27.
    • (1997) FEBS Lett. , vol.420 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 10
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto Encyclopedia of Genes and Genomes
    • Kanehisa, M. and Goto, S. (2000). KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res. 28, 27-30.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 11
    • 0032776303 scopus 로고    scopus 로고
    • Molecular interaction map of the mammalian cell cycle control and DNA repair systems
    • Kohn, K. W. (1999). Molecular interaction map of the mammalian cell cycle control and DNA repair systems. Mol. Biol. Cell. 10, 2703-2734.
    • (1999) Mol. Biol. Cell. , vol.10 , pp. 2703-2734
    • Kohn, K.W.1
  • 12
    • 0037208158 scopus 로고    scopus 로고
    • TRANSPATH®: An integrated database on signal transduction and a tool for array analysis
    • Krull, M., Voss, N., Choi, C., Pistor, S., Potapov, A. and Wingender, E. (2003). TRANSPATH®: An integrated database on signal transduction and a tool for array analysis. Nucleic Acids Res. 31, 97-100.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 97-100
    • Krull, M.1    Voss, N.2    Choi, C.3    Pistor, S.4    Potapov, A.5    Wingender, E.6
  • 13
    • 33745198999 scopus 로고    scopus 로고
    • Simulated cell division processes of the xenopus cell cycle pathway by Genomic Object Net
    • Matsui, M., Fujita, S., Suzuki, S., Matsuno, H. and Miyano, S. (2004). Simulated cell division processes of the xenopus cell cycle pathway by Genomic Object Net. J. Integrative Bioinfomatics, 0003.
    • (2004) J. Integrative Bioinfomatics , pp. 0003
    • Matsui, M.1    Fujita, S.2    Suzuki, S.3    Matsuno, H.4    Miyano, S.5
  • 14
    • 0033648431 scopus 로고    scopus 로고
    • Hybrid Petri net representation of gene regulatory network
    • Matsuno, H., Doi, A., Nagasaki, M. and Miyano, S. (2000). Hybrid Petri net representation of gene regulatory network. Pac. Symp. Biocomput. 5, 338-349.
    • (2000) Pac. Symp. Biocomput. , vol.5 , pp. 338-349
    • Matsuno, H.1    Doi, A.2    Nagasaki, M.3    Miyano, S.4
  • 15
    • 0041627864 scopus 로고    scopus 로고
    • Boundary formation by notch signaling in Drosophila multicellular systems: Experimental observations and a gene network modeling by Genomic Object Net
    • Matsuno, H., Murakami, R., Yamane, R., Yamasaki, N., Fujita, S., Yoshimori, H. and Miyano, S. (2003a). Boundary formation by notch signaling in Drosophila multicellular systems: Experimental observations and a gene network modeling by Genomic Object Net. Pac. Symp. Biocomput. 8, 152-163.
    • (2003) Pac. Symp. Biocomput. , vol.8 , pp. 152-163
    • Matsuno, H.1    Murakami, R.2    Yamane, R.3    Yamasaki, N.4    Fujita, S.5    Yoshimori H. Miyano, S.6
  • 16
    • 0345170900 scopus 로고    scopus 로고
    • Biopathways representation and simulation on hybrid functional Petri net
    • Matsuno, H., Tanaka, Y., Aoshima, H., Doi, A., Matsui, M. and Miyano, S. (2003b). Biopathways representation and simulation on hybrid functional Petri net. In Silico Biol. 3, 0032.
    • (2003) In Silico Biol. , vol.3 , pp. 0032
    • Matsuno, H.1    Tanaka, Y.2    Aoshima, H.3    Doi, A.4    Matsui, M.5    Miyano, S.6
  • 17
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita, T. and Reed, J. C. (1995). Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 18
    • 2642533799 scopus 로고    scopus 로고
    • Genomic Object Net: I. A platform for modeling and simulating biopathways
    • Nagasaki, M., Doi, A., Matsuno, H. and Miyano, S. (2003). Genomic Object Net: I. A platform for modeling and simulating biopathways. Appl. Bioinformatics 2, 181-184.
    • (2003) Appl. Bioinformatics , vol.2 , pp. 181-184
    • Nagasaki, M.1    Doi, A.2    Matsuno, H.3    Miyano, S.4
  • 19
    • 33745213433 scopus 로고    scopus 로고
    • Integrating biopathway databases for large-scale modeling and simulation
    • Conferences in Research and Practice in Information Technology, Y.-P. P. (ed.), Australian Computer Society
    • Nagasaki, M., Doi, A., Matsuno, H. and Miyano, S. (2004). Integrating biopathway databases for large-scale modeling and simulation. In: Conferences in Research and Practice in Information Technology, Vol. 29 - Bioinformatics, Chen, Y.-P. P. (ed.), Australian Computer Society, pp. 43-52.
    • (2004) Bioinformatics, Chen , vol.29 , pp. 43-52
    • Nagasaki, M.1    Doi, A.2    Matsuno, H.3    Miyano, S.4
  • 22
    • 0033536063 scopus 로고    scopus 로고
    • ARF stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2
    • ARF stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2. Proc. Natl. Acad. Sci. USA 96, 6937-6941.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6937-6941
    • Tao, W.1    Levine, A.J.2
  • 23
    • 0032549711 scopus 로고    scopus 로고
    • ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4α locus deletion impairs both the Rb and p53 tumor suppression pathways
    • Zhang, Y., Xiong, Y. and Yarbrough, W. G. (1998). ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4α locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 92, 725-734.
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrough, W.G.3
  • 24
    • 0033000482 scopus 로고    scopus 로고
    • Mutation in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
    • Zhang, Y. and Xiong, Y. (1999). Mutation in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53. Mol. Cell 3, 579-591.
    • (1999) Mol. Cell , vol.3 , pp. 579-591
    • Zhang, Y.1    Xiong, Y.2
  • 25
    • 0034915032 scopus 로고    scopus 로고
    • Control of p53 ubiquitination and nuclear export by MDM2 and ARF
    • Zhang, Y. and Xiong, Y. (2001). Control of p53 ubiquitination and nuclear export by MDM2 and ARF. Cell Growth Differ. 12, 175-186.
    • (2001) Cell Growth Differ. , vol.12 , pp. 175-186
    • Zhang, Y.1    Xiong, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.