The regulatory mechanism of Tremella mesenterica on steroidogenesis in MA-10 mouse Leydig tumor cells

Life Sciences

Volumn 79, Issue 6, 2006, Pages 584-590

  Chen, Yen Wen ^a   Lo, Hui Chen ^b,c   Yang, Jyuer Ger ^b,c   Chien, Chi Hsien ^a   Lee, Shi Hsiung ^a   Tseng, Chi Yu ^a   Huang, Bu Miin ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

Leydig cell; MA 10; Progesterone; Tremella mesenterica

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; BUCLADESINE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CHORIONIC GONADOTROPIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENZYME INHIBITOR; FORSKOLIN; PREGNENOLONE; PROGESTERONE; STEROIDOGENIC ACUTE REGULATORY PROTEIN;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; LEYDIG CELL TUMOR; MALE; MOUSE; MUSHROOM; NONHUMAN; PROGESTERONE SYNTHESIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEROIDOGENESIS; TREMELLA MESENTERICA;

3-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; BASIDIOMYCOTA; CELL LINE, TUMOR; CHORIONIC GONADOTROPIN; CYTOCHROME P-450 ENZYME SYSTEM; FORSKOLIN; LEYDIG CELL TUMOR; LEYDIG CELLS; MALE; MEDICINE, CHINESE TRADITIONAL; MICE; PHOSPHOPROTEINS; PROGESTERONE;

BASIDIOMYCOTA; TREMELLA MESENTERICA;

EID: 33745211219     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.02.003     Document Type: Article

References (21)

1. Ascoli M. Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptor and steroidogenic responses. Endocrinology 108 (1981) 88-95
2. Ascoli M., Fanelli F., and Segaloff D.L. The lutropin/choriogonadotropin receptor, a 2002 perspective. Endocrine Review 23 (2002) 141-174
3. Chen L.Y., Huang Y.L., Liu M.Y., Leu S.F., and Huang B.M. Effects of amphetamine on steroidogenesis in MA-10 mouse Leydig tumor cells. Life Sciences 72 (2003) 1983-1995
4. Chen Y.C., Huang Y.L., and Huang B.M. Cordyceps sinensis mycelium activates PKA and PKC signal pathways to stimulate steroidogenesis in MA-10 mouse Leydig tumour cells. International Journal of Biochemistry and Cell Biology 37 (2005) 214-223
5. Cherradi N., Defaye G., and Chambaz E.M. Characterization of the 3 beta-hydroxysteroid dehydrogenase activity associated with bovine adrenocortical mitochondria. Endocrinology 134 (1994) 1358-1364
6. Clark B.J., Wells J., King S.R., and Stocco D.M. The purification, cloning, and expression of a novel LH-induced mitochondrial protein in MA-10 mouse Leydig tumor cells: characterization of the steroidogenic acute regulatory protein (StAR). Journal of Biological Chemistry 269 (1994) 28314-28322
7. Desaubry L., Shoshani I., and Johnson R.A. Inhibition of asenylyl cyclase by a family of newly synthesized adenine nucleoside 3′-polyphosphated. Journal of Biological Chemistry 271 (1996) 14028-14034
8. Hunag B.M., Stocco D.M., Hutson J.C., and Norman R.L. Corticotropin-releasing hormone stimulates steroidogenesis in mouse Leydig cells. Biology of Reproduction 53 (1995) 620-626
9. Laurich V.M., Trbovich A.M., O'Neill F.H., Houk C.P., Sluss P.M., Payne A.H., Donahoe P.K., and Teixeira J. Mullerian inhibiting substance blocks the protein kinase A-induced expression of cytochrome p450 17alpha-hydroxylase/C(17-20) lyase mRNA in a mouse Leydig cell line independent of cAMP responsive element binding protein phosphorylation. Endocrinology 143 (2002) 3351-3360
10. Liu B. Chinese Medical Fungi (1978), Shansi People's Publisher, China
11. Lo H.C., Yang J.G., Liu B.C., Chen Y.W., Huang Y.L., Poon S.L., Liu M.Y., and Huang B.M. The effects of Tremella aurantia on testosterone and corticosterone productions in normal and diabetic rats. Archives of Andrology 50 (2004) 395-404
12. Lo H.C., Chen Y.W., Chien C.H., Tseng C.Y., Kuo Y.M., and Huang B.M. Effects of Tremella mesenterica on steroidogenesis in MA-10 mouse Leydig tumor cells. Archives of Andrology 51 (2005) 285-294
13. Manna P.R., Wang X.J., and Stocco D.M. Involvement of multiple transcription factors in the regulation of steroidogenic acute regulatory protein gene expression. Steroids 68 (2003) 1125-1134
14. Mellon S.H., and Vaisse C. cAMP regulates P450scc gene expression by a cycloheximide-insensitive mechanism in cultured mouse Leydig MA-10 cells. Proceedings of the National Academy of Sciences of the United States of America 86 (1989) 7775-7779
15. Payne A.H., Hardy M.P., and Russel L.D. The Leydig Cell (1996), Cache River Press, USA
16. Richard J.S. New signaling pathways for hormones and cyclic adenosine 3′, 5′-monophosphate action in endocrine cells. Molecular Endocrinology 15 (2001) 209-218
17. Saez J.M. Leydig cells: endocrine, paracrine, and autocrine regulation. Endocrine Review 15 (1994) 574-626
18. Simpson E.R. Cholesterol side-chain cleavage, cytochrome P450, and the control of steroidogenesis. Molecular and Cellular Endocrinology 13 (1979) 213-227
19. Sulimovici S., Bartoov B., and Lunenfeld B. Localization of 3β-hydroxysteroid dehydrogenase in the inner membrane subfraction of rat testis mitochondria. Biochimica et biophysica acta 321 (1973) 27-40
20. Stocco D.M., and Clark B.J. Regulation of the acute production of steroid in steroidogenic cells. Endocrine Review 17 (1996) 221-244
21. Valenti S., Guido R., Fazzuoli L., Barreca A., Giusti M., and Giordano G. Decreased steroidogenesis and cAMP production in vitro by Leydig cells isolated from rats made hypothyroid during adulthood. International Journal of Andrology 20 (1997) 279-286