Treatment of squamous carcinoma in mice with a vaccine enriched for cells that induce immunity to squamous carcinoma - A new vaccination strategy

International Journal of Cancer

Volumn 119, Issue 2, 2006, Pages 339-348

  Chopra, Amla ^a   Kim, Tae Sung ^b   O Sullivan, InSug ^a   Martinez, Don ^a   Cohen, Edward P ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b Korea University   (South Korea)

Author keywords

CTLs; DNA based vaccine; Immunotherapy; Lung cancer; Squamous cell carcinoma

Indexed keywords

CANCER VACCINE; DNA FRAGMENT; DNA VACCINE; GAMMA INTERFERON; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CANCER SURVIVAL; CD8+ T LYMPHOCYTE; CELL POPULATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; DNA INTEGRATION; DNA TRANSFER; FEMALE; FIBROBLAST; GENETIC TRANSFECTION; IMMUNOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR IMMUNITY; VACCINATION;

ANIMALS; CANCER VACCINES; CARCINOMA, SQUAMOUS CELL; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; INTERFERON TYPE II; MICE; MICE, INBRED DBA; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 33745209715     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.21844     Document Type: Article

References (50)

1. Morse MA, Garst J, Osada T, Khan S, Hobeika A, Clay TM, Valente N, Shreeniwas R, Sutton MA, Delcayre A, Hsu DH, Le Pecq JB, et al. A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer. Cancer Res 2005;65:553-61.
2. Ishikawa A, Motohashi S, Ishikawa E, Fuchida H, Higashino K, Otsuji M, Iizasa T, Nakayama T, Taniguchi M, Fujisawa T. A phase I study of alpha-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer. Clin Cancer Res 2005;11:1910-7.
3. So T, Takenoyama M, Ichiki Y, Mizukami M, So T, Hanagiri T, Sugio K, Yasumoto K. A different pattern of cytotoxic T lymphocyte recognition against primary and metastatic tumor cells in a patient with non small cell lung carcinoma. Cancer 2005;103:200-8.
4. Maione P, Rossi A, Airoma G, Ferrara C, Castaldo V, Gridelli C. The role of targeted therapy in non-small cell lung cancer. Crit Rev Oncol Hematol 2004;51:29-44.
5. Kuss I, Schaefer C, Godfrey TE, Ferris RL, Harris JM, Gooding W, Whiteside TL. Recent thymic emigrants and subsets of naive and memory T cells in the circulation of patients with head and neck cancer. Clin Immunol 2005;16:27-36.
6. Meissner M, Reichert TE, Kunkel M, Gooding W, Whiteside TL, Ferrone S, Seliger B. Defects in the human leukocyte antigen class I antigen processing machinery in head and neck squamous cell carcinoma: Association with clinical outcome. Clin Cancer Res 2005;11: 2552-60.
7. Whiteside TL. Immunobiology of head and neck cancer. Cancer Metastasis Rev 2005;24:95-105.
8. de Zoeten EF, Carr-Brendel V, Cohen EP. Resistance to melanoma in mice immunized with semi-allogeneic fibroblasts transfected with genomic DNA from melanoma cells. J Immunol 1998;160:2915-22.
9. de Zoeten E, Carr-Brendel V, Markovic D, Taylor-Papadimitriou J, Cohen EP. Immunity to breast cancer in mice immunized with semi-allogeneic fibroblasts transfected with DNA from breast cancer cells. J Immunol 1999;162:6934-41.
10. Kim TS, Cohen EP. Immunity to breast cancer in mice immunized with fibroblasts transfected with a cDNA expression library derived from small numbers of breast cancer cells. Cancer Gene Ther 2005;12:890-9.
11. O-Sullivan I, Ng LK, Martinez DM, Kim TS, Chopra A, Cohen EP. Immunity to squamous carcinoma in mice immunized with dendritic cells transfected with genomic DNA from squamous carcinoma cells. Cancer Gene Ther 2005;12:825-34.
12. Whiteside TL, Gambotto A, Albers A, Stanson J, Cohen EP. Human tumor-derived genomic DNA transduced into a recipient cell induces tumor-specific immune responses ex vivo. Proc Natl Acad Sci USA 2002;99:9415-20.
13. Ostrand-Rosenberg S, Thakur A, Clements V. Rejection of mouse sarcoma cells after transfection of MHC class II genes. J Immunol 1990; 144:4068-71.
14. Fearon ER, Itaya T, Hunt B, Vogelstein B, Frost P. Induction in a murine tumor of immunogenic tumor variants by transfection with a foreign gene. Cancer Res 1988;48:2975-80.
15. Nabel GJ, Gordon D, Bishop DK, Nickoloff BJ, Yang Z-Y, Aruga A, Cameron MJ, Nabel EG, Chang AE. Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes. Proc Natl Acad Sci USA 1996;93:15388-93.
16. DeBniyne L. Treatment of malignancy by direct gene transfer of a foreign MHC class I molecule. Cancer Immunol Immunother 1996: 43:180-9.
17. Wigler M, Pellicer A, Silverstein S, Axel R, Urlaub G, Chasin L. DNA-mediated transfer of the adenine phosphoribosyl transferase locus into mammalian cells. Proc Natl Acad Sci USA 1979;76:1373-6.
18. Sun T, de Zoeten EF, Carr-Brendel V, Cohen EP. Immunization with interleukin-2-secreting allogeneic cells transfected with DNA from mouse melanoma cells induces immune responses that prolong the lives of mice with melanoma. Cancer Gene Ther 1998;5:110-8.
19. Xie W, de Zoeten EF, Carr-Brendel V, Cohen EP. Co-expression of immunogenic determinants by the same cellular immunogen is required for an optimum immunotherapeutic benefit in mice with melanoma. Cancer Immunol Immunother 1998;45:217-24.
20. Kim TS, Chung SW, Kim SH, Kang SN, Kang AT. Therapeutic antitumor response induced with epitope-pulsed fibroblasts genetically engineered for B7.1 expression and IFN-gamma secretion. Int J Cancer 2002;87:427-33.
21. Butz EA, Bevan MJ. Differential presentation of the same MHC class 1 epitopes by fibroblasts and dendritic cells. J Immunol 1998;160: 2139-44.
22. Kim TS, Chung SW, Hwang SY. Augmentation of antitumor immunity by genetically engineered fibroblast cells to express both B7.1 and interleukin-7. Vaccine 2000;18:2886-94.
23. Chesney J, Bacher M, Bender A, Bucala R. The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ. Proc Natl Acad Sci USA 1997;94:6307-12.
24. Kundig TM, Bachmann MF, DiPaolo C, Simaind JJL, Battegay M, Lother H, Gessner A, Kuhlcke K, Ohashi PS, Hengartner H, Zinkernagel RM. Fibroblasts as efficient antigen-presenting cells in lymphoid organs. Science 1995;268:1343-5.
25. American Cancer Society: Cancer Facts and Figures. 2005.
26. Tyczynski JE, Berkel HJ. Mortality from lung cancer and tobacco smoking in Ohio (U.S.): will increasing smoking prevalence reverse current decreases in mortality? Cancer Epidemiol Biomarkers Prev 2005;14:1182-7.
27. Green PM, Davis MA. Lung cancer in African-Americans. J Natl Black Nurses Assoc 2004;15:54-60.
28. Marugame T, Yoshimi I, Kamo K, Imamura Y, Kaneko S, Mizuno S, Sobue T. Trends in lung cancer mortality among young adults in Japan. Jpn J Clin Oncol 2005;35:177-80.
29. Alberg AJ, Brock MV, Samet JM. Epidemiology of lung cancer: looking to the future. J Clin Oncol 2005;23:3175-85.
30. Hirschowitz EA, Foody T, Kryscio R, Dickson L, Sturgill J, Yannelli J. Autologous dendritic cell vaccines for non-small-cell lung cancer. J Clin Oncol 2004;22:2808-15.
31. Raez LE, Cassileth PA, Schlesselman JJ, Sridhar K, Padmanabhan S, Fisher EZ, Baldie PA, Podack ER. Allogeneic vaccination with a B7.1 HLA-A gene-modified adenocarcinoma cell line in patients with advanced non-small-cell lung cancer. J Clin Oncol 2004;22:2800-7.
32. Chang GC, Lan HC, Juang SH, Wu YC, Lee HC, Hung YM, Yang HY, Whang-Peng J, Liu KJ. A pilot clinical trial of vaccination with dendritic cells pulsed with autologous tumor cells derived from malignant pleural effusion in patients with late-stage lung carcinoma. Cancer 2005;103:763-71.
33. Xiang R, Mizutani N, Luo Y, Chiodoni C, Zhou H, Mizutani M, Ba Y, Becker JC, Reisfeld RA. A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication. Cancer Res 2005;65:553-61.
34. Akita KH, Inagaki S, Sato T, Niimi H, Maeda S, Ninomiya H, Achiwa H, Kawaguchi Y, Yamakawa Y, Fujii. p185(HER-2/neu) and p21 (CIP1/WAF1) expression in primary tumors and lymph node metastases in non-small cell lung cancer. Jpn J Cancer Res 2002;93: 1007-12.
35. Gonzalez G, Crombet T, Torres F, Catala M, Alfonso L, Osorio M, Neninger E, Garcia B, Mulet A, Perez R, Lage R. Epidermal growth factor-based cancer vaccine for non-small-cell lung cancer therapy. Ann Oncol 2003;14:461-6.
36. Wang T, Hopkins DA, Fan L, Fanger GR, Houghton R, Vedvick TS, Repasky E, Reed SG. A p53 homologue and a novel serine proteinase inhibitor are over-expressed in lung squamous cell carcinoma. Lung Cancer 2001;34:363-74.
37. Peltomaki P, Lothe RA, Aaltonen LA, Pylklanen L, Nystrom-Lahti M, Seruca R, David L, Holm R, Ryberg D, Haugen A, Brogger A, Borresen A-L, et al. Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome. Cancer Res 1993;53:5853-5.
38. Gonzalez-Zulueta M, Ruppert JM, Tokino K, Tsai YC, Spruck CH, Miyao N, Nichols PW, Hermann GG, Horn T, Steven K, Summerhayes IC, Sidransky D, et al. Microsatellite instability in bladder cancer. Cancer Res 1993;53:5620-3.
39. Risinger JI, Berchuck A, Kohler MF, Watson P, Lynch HT, Boyd J. Genetic instability of microsatellites in endometrial carcinoma. Cancer Res 1993;53:5100-3.
40. Han H-J, Yanagisawa A, Kato Y, Park J-G and Nakamura Y. Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Res 1993;53:5087-9.
41. Bavoux C, Leopoldino AM, Bergoglio V, O-Wang J, Ogi T, Bieth A, Judde JG, Pena SD, Poupon MF, Helleday T, Tagawa M, Machado C, et al. Up-regulation of the error-prone DNA polymerase (kappa) promotes pleiotropic genetic alterations and tumorigenesis. Cancer Res 2005;65:325-30.
42. Takahashi Y, Kondo K, Hirose T, Nakagawa H, Tsuyuguchi M, Hashimoto M, Sano T, Ochiai A, Monden Y. Microsatellite instability and protein expression of the DNA mismatch repair gene, hMLH1, of lung cancer in chromate-exposed workers. Mol Carcinog 2005;42:150-8.
43. Kaneko T, LePage GA, Shnitka TK. KLN205-a murine lung carcinoma cell line. In Vitro 1980;16:884-92.
44. Kavathas P, Herzenberg LA. Stable transformation of mouse LM cells (a transformed fibroblast cell line) for human membrane T-cell differentiation antigens, HLA and B2 microglobulin: selection by fluorescence-activated cell sorting. Proc Natl Acad Sci USA 1983;80:524-8.
45. Shih C, Shilo B-Z, Goldfarb MP, Dannenberg A, Weinberg RA. Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin. Proc Natl Acad Sci USA 1979;76:5714-8.
46. Barraclough R, Chen HJ, Davies BR, Davies MP, Ke Y, Lloyd BH, Oates A, Rudland PS. Use of DNA transfer in the induction of metastasis in experimental mammary systems. Biochem Soc Symp 1998;63:273-94.
47. Shih C, Padhy LC, Murray M, Weinberg RA. Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts. Nature 1981;290:261-4.
48. Shih C, Weinberg RA. Isolation of a transforming sequence from a human bladder carcinoma cell line. Cell 1982;29:161-9.
49. Donnelly JJ, Wahren B, Liu MA. DNA vaccines: progress and challenges. J Immunol 2005;175:633-9.
50. Bohnenkamp HR, Coleman J, Burchell JM, Taylor-Papadimitriou J, Noll T. Breast carcinoma cell lysate-pulsed dendritic cells cross-prime MUC1-specific CD8(+) T cells identified by peptide-MHC-class-I tetramers. Cell Immunol 2004;231:112-25.