Role for dopamine neurons of the rostral linear nucleus and periaqueductal gray in the rewarding and sensitizing properties of heroin

Neuropsychopharmacology

Volumn 31, Issue 7, 2006, Pages 1475-1488

  Flores, Juan A ^a   Galan Rodriguez, Beatriz ^a   Ramiro Fuentes, Susana ^a   Fernandez Espejo, Emilio ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Dopamine; Heroin; Periaqueductal; Reward; Sensitization

Indexed keywords

DIAMORPHINE; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN STEM; CELL ACTIVATION; CELL COUNT; CONDITIONING; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; DORSAL RAPHE NUCLEUS; DRUG EFFECT; DRUG SENSITIZATION; HEROIN DEPENDENCE; LOCOMOTION; MALE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; REWARD; ROSTRAL LINEAR NUCLEUS; VENTRAL TEGMENTUM;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-ANXIETY AGENTS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; DIAZEPAM; DOPAMINE; DOPAMINE ANTAGONISTS; EXPLORATORY BEHAVIOR; GENE EXPRESSION; HEROIN; IMMUNOHISTOCHEMISTRY; MALE; MAZE LEARNING; MEDULLA OBLONGATA; NARCOTICS; NEURONS; OXIDOPAMINE; PERIAQUEDUCTAL GRAY; RATS; RATS, WISTAR; REWARD; TYROSINE 3-MONOOXYGENASE;

EID: 33745203035     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300946     Document Type: Article

References (64)

1. Bardo MT, Rowlett JK, Harris MJ (1995). Conditioned place preference using opiate and stimulant drugs: a meta-analysis. Neurosci Biobehav Rev 19: 39-51.
2. Beitner-Johnson D, Nestler EJ (1991). Morphine and cocaine exert common chronic actions on tyrosine hydroxylase in dopaminergic brain reward regions. J Neurochem 57: 344-347.
3. Boundy VA, Gold SJ, Messer CJ, Chen J, Son JH, Joh TH et al (1998). Regulation of tyrosine hydroxylase promoter activity by chronic morphine in TH9.0-LacZ transgenic mice. J Neurosci 18: 9989-9995.
4. Bouthenet ML, Martres MP, Sales N, Schwartz JC (1987). A detailed mapping of dopamine D-2 receptors in rat central nervous system by autoradiography with [125I]iodosulpride. Neuroscience 20: 117-155.
5. Brodkin ES, Kosten TA, Haile CN, Heninger GR, Carlezon Jr WA, Jatlow P et al (1999). Dark Agouti and Fischer 344 rats: differential behavioral responses to morphine and biochemical differences in the ventral tegmental area. Neuroscience 88: 1307-1315.
6. Buma P, Veening J, Hafmans T, Joosten H, Nieuwenhuys R (1992). Ultrastructure of the periaqueductal grey matter of the rat: an electron microscopical and horseradish peroxidase study. J Comp Neurol 319: 519-535.
7. Caillé S, Espejo EF, Reneric JP, Cador M, Koob GF, Stinus L (1999). Total neurochemical lesion of noradrenergic neurons of the locus coeruleus does not alter either naloxone-precipitated or spontaneous opiate withdrawal nor does it influence ability of clonidine to reverse opiate withdrawal. J Pharmacol Exp Therap 290: 881-892.
8. Caine SB, Heinrichs SC, Coffin VL, Koob GF (1995). Effects of the dopamine D-1 antagonist SCH-23390 microinjected into the accumbens, amygdala or striatum on cocaine self-administration in the rat. Brain Res 692: 47-56.
9. Carlezon WA, Boundy VA, Haile CN, Lane SB, Kalb RG, Neve RL et al (1997). Sensitization to morphine induced by viral-mediated gene transfer. Science 277: 812-814.
10. Cunningham ST, Kelley AE (1993). Hyperactivity and sensitization to psychostimulants following cholera toxin infusion into the nucleus accumbens. J Neurosci 13: 2342-2350.
11. Di Chiara G, Tanda G, Bassareo V, Pontieri F, Acquas E, Fenu S et al (1999). Drug addiction as a disorder of associative learning: role of nucleus accumbens shell/extended amygdala. In: McGinty J (ed). Advancing from the Ventral Striatum to the Extended Amygdala: Implications for Neuropsychiatry and Drug Abuse (Series: Annals of the New York Academy of Sciences, Vol 877), Annals New York Academy of Sciences: New York. pp 461-485.
12. Espejo EF (1997). Selective dopamine depletion within the medial prefrontal cortex induces anxiogenic-like effects in rats placed on the elevated plus-maze. Brain Res 762: 281-284.
13. Espejo EF, Miñano J (1999). Prefrontocortical dopamine depletion induces antidepressant-like effects in rats, and alters the profile of desipramine during Porsolt's test. Neuroscience 88: 609-615.
14. Finlay JM, Zigmond MJ, Abercrombie ED (1995). Increased dopamine and norepinephrine release in medial prefrontal cortex induced by acute and chronic stress: effects of diazepam. Neuroscience 64: 619-628.
15. Fitzgerald LW, Ortiz J, Hamedani AG, Nestler EJ (1996). Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents. J Neurosci 16: 274-282.
16. Fletcher PJ, Ming ZH, Higgins GA (1993). Conditioned place preference induced by microinjection of 8-OH-DPAT into the dorsal or median raphe nucleus. Psychopharmacology (Berl) 113: 31-36.
17. Fujita M, Shimada S, Nishimura T, Uhl GR, Tohyama M (1993). Ontogeny of dopamine transporter mRNA expression in the rat brain. Brain Res Mol Brain Res 19: 222-226.
18. Grove EA (1988). Neural associations of the substantia innominata in the rat: afferent connections. J Comp Neurol 277: 315-346.
19. Gundersen HJG, Jensen EB (1987). The efficiency of systematic sampling in stereology and its prediction. J Microsc 147: 229-263.
20. Haj-Dahmane S, Shen RY (2000). Dopamine D2-like receptor activation depolarizes rat dorsal raphe serotonin neurons. Soc Neurosci Abs 26: 1419.
21. Hasue RH, Shammah-Lagnado SJ (2002). Origin of the dopaminergic innervation of the central extended amygdala and accumbens shell: a combined retrograde tracing and immunohistochemical study in the rat. J Comp Neurol 454: 15-33.
22. Hökfelt T, Johansson O, Fuxe K, Goldstein M, Park D (1976). Immunohistochemical studies on the localization and distribution of monoamine neuron systems in the rat brain. I. Tyrosine hydroxylase in the mes- and diencephalon. Med Biol 54: 427-453.
23. Hökfelt T, Martensson R, Björklund A, Kleinau S, Goldstein M (1984). Distributional maps of tyrosine-hydroxylase-immunoreactive neurons in the rat brain. In: Björklund A, Hökfelt T (eds). Classical Transmitters in the CNS (Series Handbook of Chemical Neuroanatomy, Vol 2). Elsevier: Amsterdam. pp 277-379.
24. Kilty JE, Lorang D, Amara SG (1991). Cloning and expression of cocaine-sensitive rat dopamine transporter. Science 254: 578-579.
25. Koob GF, Vaccarino FJ, Amalric M, Bloom FE (1986). Neurochemical substrates for opiate reinforcement. NIDA Res Monogr 71: 146-164.
26. Kumer SC, Vrana KE (1996). Intrincate regulation of tyrosine hydroxylase activity and gene expression. J Neurochem 67: 443-462.
27. Lagares A, Avendaño C (1999). An efficient method to estimate cell number and volume in multiple dorsal root ganglia. Acta Stereol 18: 185-195.
28. Lindvall O, Björklund A (1974). The organization of the ascending catecholamine neuron systems in the rat brain as revealed by the glyoxilic acid fluorescence method. Acta Physiol Scand Suppl 412: 1-48.
29. Lindvall O, Björklund A, Moore RY, Stenevi U (1974). Mesencephalic dopamine neurons projecting to neocortex. Brain Res 81: 325-331.
30. Marinelli M, Le Moal M, Piazza PV (1998). Sensitization to the motor effects of contingent infusions of heroin but not of kappa agonist RU 51599. Psychopharmacology 139: 281-285.
31. Martin-Ruiz R, Ugedo L, Honrubia MA, Mengod G, Artigas F (2001). Control of serotonergic neurons in rat brain by dopaminergic receptors outside the dorsal raphe nucleus. J Neurochem 77: 762-775.
32. Messer CJ, Eisch AJ, Carlezon WA, Whisler K, Shen L, Wolf DH et al (2000). Role for GDNF in biochemical and behavioral adaptations to drugs of abuse. Neuron 26: 247-257.
33. Miserendino MJ, Nestler EJ (1995). Behavioral sensitization to cocaine: modulation by the cyclic AMP system in the nucleus accumbens. Brain Res 674: 299-306.
34. Moore RY, Bloom FE (1978). Central catecholamine neuron systems: anatomy and physiology of the dopamine systems. Ann Rev Neurosci 1: 129-169.
35. Nestler EJ (2001). Molecular basis of long-term plasticity underlying addiction. Nat Rev Neurosci 2: 119-128.
36. Nestler EJ, Aghajanian GK (1997). Molecular and cellular basis of addiction. Science 278: 58-63.
37. Nye HE, Nestler EJ (1996). Induction of chronic Fos-related antigens in rat brain by chronic morphine administration. Mol Pharmacol 49: 636-645.
38. Oades RD, Halliday GM (1987). Ventral tegmental (A10) system: neurobiology. I. Anatomy and connectivity. Brain Res Rev 12: 117-165.
39. Ottersen OP (1981). Afferent connections to the amygdaloid complex of the rat with some observations in the cat. III. Afferents from the lower brainstem. J Comp Neurol 202: 335-356.
40. Paxinos G, Watson C (1997). The Rat Brain in Stereotaxic Coordinates. Academic Press: Sydney.
41. Peyron C, Luppi PH, Kitahama K, Fort P, Hermann DM, Jouvet M (1995). Origin of the dopaminergic innervation of the rat dorsal raphe nucleus. Neuroreport 6: 2527-2531.
42. Phillipson OT (1979). The cytoarchitecture of the interfascicular nucleus and ventral tegmental area of Tsai in the rat. J Comp Neurol 187: 85-98.
43. Pontieri FE, Monnazzi P, Scontrini A, Buttarelli FR, Patacchioli FR (2001). Behavioral sensitization to heroin by cannabinoid pretreatment in the rat. Eur J Pharmacol 421: R1-R3.
44. Robinson TE, Berridge KC (1993). The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Rev 18: 247-291.
45. Rodgers RJ, Cole JC (1994). The elevated plus-maze: pharmacology, methodology and ethology. In: Cooper SJ, Hendrie CA (eds). Ethology and Psychopharmacology. Wiley: New York. pp 9-44.
46. Schulteis G, Markou A, Gold LH, Stinus L, Koob GF (1994). Relative sensitivity to naloxone of multiple indices of opiate withdrawal: a quantitative dose-response analysis. J Pharmacol Exp Ther 271: 1391-1398.
47. Seeman P, Van Tol HH (1994). Dopamine receptor pharmacology. Trends Pharmacol Sci 15: 264-270.
48. Segal DS, Kuczenski R (1992). Repeated cocaine administration induces behavioral sensitization and corresponding decreased extracellular dopamine responses in caudate and accumbens. Brain Res 577: 351-355.
49. Self DW, McClenahan AW, Beitner-Johnson D, Terwilliger RZ, Nestler EJ (1995). Biochemical adaptations in the mesolimbic dopamine system in response to heroin self-administration. Synapse 21: 312-318.
50. Self DW, Nestler EJ (1995). Molecular mechanisms of drug reinforcement and addiction. Annu Rev Neurosci 18: 463-495.
51. Shimada S, Kitayama S, Walther D, Uhl G (1992). Dopamine transporter mRNA: dense expression in ventral midbrain neurons. Brain Res Mol Brain Res 13: 359-362.
52. Shippenberg TS, Elmer GI (1998). The neurobiology of opiate reinforcement. Crit Rev Neurobiol 12: 267-303.
53. Sklair-Tavron L, Shi WX, Lane SB, Harris HW, Bunney BS, Nestler EJ (1996). Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons. Proc Natl Acad Sci USA 93: 11202-11207.
54. Sterio DC (1984). The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc 134: 127-136.
55. Stewart J, Badiani A (1993). Tolerance and sensitization to the behavioral effects of drugs. Behav Pharmacol 4: 289-312.
56. Stinus L, Le Moal M, Koob GF (1990). Nucleus accumbens and amygdala are possible substrates for the aversive stimulus effects of opiate withdrawal. Neuroscience 37: 767-773.
57. Terwilliger RZ, Beitner-Johnson D, Sevarino KA, Crain SM, Nestler EJ (1991). A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function. Brain Res 548: 100-110.
58. Tzschentke TM (1998). Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues. Prog Neurobiol 56: 613-672.
59. Unguez GA, Schneider JS (1988). Dopaminergic dorsal raphe nucleus in cats and monkeys are sensitive to the toxic effects of MPTP. Neurosci Lett 94: 218-223.
60. Vanderschuren LJMJ, Kalivas PW (2000). Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacology 151: 99-120.
61. Vertes RP (1991). A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat. J Comp Neurol 313: 643-668.
62. Williams JT, Christie MJ, Manzoni O (2001). Cellular and synaptic adaptations mediating opioid dependence. Physiol Rev 81: 299-343.
63. Wilson MA, Burghardt PR, Ford KA, Wilkinson MB, Primeaux SD (2004). Anxiolytic effects of diazepam and ethanol in two behavioral models: comparison of males and females. Pharmacol Biochem Behav 78: 445-458.
64. Wise RA (1989). Opiate reward: sites and substrates. Neurosci Biobehav Rev 13: 29-133.