In vivo effect of tramadol on locus coeruleus neurons is mediated by α2-adrenoceptors and modulated by serotonin

Neuropharmacology

Volumn 51, Issue 1, 2006, Pages 146-153

  Berrocoso, Esther ^a   Micó, Juan Antonio ^a   Ugedo, Luisa ^b  

^a School of Medicine   (Spain)

^b UNIVERSITY OF CÁDIZ   (Spain)

Author keywords

2 Adrenoceptor; 5 HT1A receptors; Locus coeruleus; Opioid receptor; Serotonin; Tramadol

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ANALGESIC AGENT; FENCLONINE; IDAZOXAN; NALOXONE; OPIATE ANTAGONIST; OPIATE RECEPTOR; SEROTONIN; SEROTONIN 1A AGONIST; TRAMADOL;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CATECHOLAMINE SYNTHESIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG SELECTIVITY; LOCUS CERULEUS; LOW DRUG DOSE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONIN METABOLISM; SEROTONINERGIC SYSTEM;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; ANTIDEPRESSIVE AGENTS; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ELECTROPHYSIOLOGY; EXTRACELLULAR SPACE; FENCLONINE; LOCUS COERULEUS; MALE; NARCOTIC ANTAGONISTS; NARCOTICS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, OPIOID, MU; SEROTONIN; SEROTONIN AGENTS; SEROTONIN AGONISTS; TRAMADOL;

EID: 33745182875     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2006.03.013     Document Type: Article

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