Functional interaction of nuclear receptor coactivator 4 with aryl hydrocarbon receptor

Biochemical and Biophysical Research Communications

Volumn 346, Issue 2, 2006, Pages 526-534

  Kollara, Alexandra ^a,b   Brown, Theodore J ^a,b,c  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

AhR; AR; ARA70; ARNT; Coactivator; ELE1; NcoA4; RFG; T47D; TCDD

Indexed keywords

ANDROGEN RECEPTOR; AROMATIC HYDROCARBON RECEPTOR; CARRIER PROTEINS AND BINDING PROTEINS; DIOXIN; NUCLEAR RECEPTOR COACTIVATOR 4; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL CULTURE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS MEMBRANE; CELL STRAIN COS1; CONTROLLED STUDY; CYTOPLASM; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN VARIANT; RNA SPLICING; TRANSCRIPTION INITIATION;

AMINO ACID MOTIFS; ANIMALS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; CELL LINE; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; ENZYME ACTIVATION; HUMANS; MICE; ONCOGENE PROTEINS; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ARYL HYDROCARBON; SIGNAL TRANSDUCTION; TETRACHLORODIBENZODIOXIN; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 33745176558     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.05.148     Document Type: Article

References (47)

1. Gu Y.Z., Hogenesch J.B., and Bradfield C.A. The PAS superfamily: sensors of environmental and developmental signals. Annu. Rev. Pharmacol. Toxicol. 40 (2000) 519-561
2. Morrow D., Qin C., Smith III R., and Safe S. Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation. J. Steroid Biochem. Mol. Biol. 88 (2004) 27-36
3. Schaufler K., Haslmayer P., Jager W., Pec M., and Thalhammer T. The environmental toxin 2,3,7,8-tetrachlorodibenzo-p-dioxin induces cytochrome P450 activity in high passage PC 3 and DU 145 human prostate cancer cell lines. Int. J. Mol. Med. 9 (2002) 411-416
4. Spink D.C., Spink B.C., Cao J.Q., DePasquale J.A., Pentecost B.T., Fasco M.J., Li Y., and Sutter T.R. Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells. Carcinogenesis 19 (1998) 291-298
5. Peter Guengerich F., Martin M.V., McCormick W.A., Nguyen L.P., Glover E., and Bradfield C.A. Aryl hydrocarbon receptor response to indigoids in vitro and in vivo. Arch. Biochem. Biophys. 423 (2004) 309-316
6. Phelan D., Winter G.M., Rogers W.J., Lam J.C., and Denison M.S. Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin. Arch. Biochem. Biophys 357 (1998) 155-163
7. Savouret J.F., Antenos M., Quesne M., Xu J., Milgrom E., and Casper R.F. 7-Ketocholesterol is an endogenous modulator for the arylhydrocarbon receptor. J. Biol. Chem. 276 (2001) 3054-3059
8. Petrulis J.R., and Perdew G.H. The role of chaperone proteins in the aryl hydrocarbon receptor core complex. Chem. Biol. Interact. 141 (2002) 25-40
9. Swanson H.I. DNA binding and protein interactions of the AHR/ARNT heterodimer that facilitate gene activation. Chem. Biol. Interact. 141 (2002) 63-76
10. Fujii-Kuriyama Y., and Mimura J. Molecular mechanisms of AhR functions in the regulation of cytochrome P450 genes. Biochem. Biophys. Res. Commun. 338 (2005) 311-317
11. Hankinson O. The aryl hydrocarbon receptor complex. Annu. Rev. Pharmacol. Toxicol. 35 (1995) 307-340
12. Whitlock Jr. J.P. Induction of cytochrome P4501A1. Annu. Rev. Pharmacol. Toxicol. 39 (1999) 103-125
13. Nguyen T.A., Hoivik D., Lee J.E., and Safe S. Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex. Arch. Biochem. Biophys. 367 (1999) 250-257
14. Kumar M.B., Tarpey R.W., and Perdew G.H. Differential recruitment of coactivator RIP140 by Ah and estrogen receptors. Absence of a role for LXXLL motifs. J. Biol. Chem. 274 (1999) 22155-22164
15. Kobayashi A., Numayama-Tsuruta K., Sogawa K., and Fujii-Kuriyama Y. CBP/p300 functions as a possible transcriptional coactivator of Ah receptor nuclear translocator (Arnt). J. Biochem. (Tokyo) 122 (1997) 703-710
16. Beischlag T.V., Wang S., Rose D.W., Torchia J., Reisz-Porszasz S., Muhammad K., Nelson W.E., Probst M.R., Rosenfeld M.G., and Hankinson O. Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex. Mol. Cell. Biol. 22 (2002) 4319-4333
17. Evangelou A., Letarte M., Jurisica I., Sultan M., Murphy K.J., Rosen B., and Brown T.J. Loss of coordinated androgen regulation in nonmalignant ovarian epithelial cells with BRCA1/2 mutations and ovarian cancer cells. Cancer Res. 63 (2003) 2416-2424
18. Kollara A., Kahn H.J., Marks A., and Brown T.J. Loss of androgen receptor associated protein 70 (ARA70) expression in a subset of HER2-positive breast cancers. Breast. Cancer Res. Treat. 67 (2001) 245-253
19. Magklara A., Brown T.J., and Diamandis E.P. Characterization of androgen receptor and nuclear receptor co-regulator expression in human breast cancer cell lines exhibiting differential regulation of kallikreins 2 and 3. Int. J. Cancer 100 (2002) 507-514
20. Nessler-Menardi C., Jotova I., Culig Z., Eder I.E., Putz T., Bartsch G., and Klocker H. Expression of androgen receptor coregulatory proteins in prostate cancer and stromal-cell culture models. Prostate 45 (2000) 124-131
21. Shaw P.A., Rittenberg P.V., and Brown T.J. Activation of androgen receptor-associated protein 70 (ARA70) mRNA expression in ovarian cancer. Gynecol. Oncol. 80 (2001) 132-138
22. Alen P., Claessens F., Schoenmakers E., Swinnen J.V., Verhoeven G., Rombauts W., and Peeters B. Interaction of the putative androgen receptor-specific coactivator ARA70/ELE1alpha with multiple steroid receptors and identification of an internally deleted ELE1beta isoform. Mol. Endocrinol. 13 (1999) 117-128
23. Yeh S., and Chang C. Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells. Proc. Natl. Acad. Sci. USA 93 (1996) 5517-5521
24. Heisler L.E., Evangelou A., Lew A.M., Trachtenberg J., Elsholtz H.P., and Brown T.J. Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor. Mol. Cell. Endocrinol. 126 (1997) 59-73
25. Sambrook J., and Russell D.W. Molecular Cloning: A Laboratory Manual. third ed. (2001), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
26. Rahman M.M., Miyamoto H., Takatera H., Yeh S., Altuwaijri S., and Chang C. Reducing the agonist activity of antiandrogens by a dominant-negative androgen receptor coregulator ARA70 in prostate cancer cells. J. Biol. Chem. 278 (2003) 19619-19626
27. He B., Minges J.T., Lee L.W., and Wilson E.M. The FXXLF motif mediates androgen receptor-specific interactions with coregulators. J. Biol. Chem. 277 (2002) 10226-10235
28. Heinlein C.A., Ting H.J., Yeh S., and Chang C. Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma. J. Biol. Chem. 274 (1999) 16147-16152
29. Zhou Z.X., He B., Hall S.H., Wilson E.M., and French F.S. Domain interactions between coregulator ARA(70) and the androgen receptor (AR). Mol. Endocrinol. 16 (2002) 287-300
30. Hu Y.C., Yeh S., Yeh S.D., Sampson E.R., Huang J., Li P., Hsu C.L., Ting H.J., Lin H.K., Wang L., Kim E., Ni J., and Chang C. Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer. J. Biol. Chem. 279 (2004) 33438-33446
31. Ting H.J., Bao B.Y., Hsu C.L., and Lee Y.F. Androgen-receptor coregulators mediate the suppressive effect of androgen signals on vitamin D receptor activity. Endocrine 26 (2005) 1-9
32. Savkur R.S., and Burris T.P. The coactivator LXXLL nuclear receptor recognition motif. J. Pept. Res. 63 (2004) 207-212
33. Rowan B.G., Garrison N., Weigel N.L., and O'Malley B.W. 8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein. Mol. Cell. Biol. 20 (2000) 8720-8730
34. Wu R.C., Qin J., Yi P., Wong J., Tsai S.Y., Tsai M.J., and O'Malley B.W. Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol. Cell 15 (2004) 937-949
35. Jain S., Maltepe E., Lu M.M., Simon C., and Bradfield C.A. Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse. Mech. Dev. 73 (1998) 117-123
36. Fernandez-Salguero P.M., Ward J.M., Sundberg J.P., and Gonzalez F.J. Lesions of aryl-hydrocarbon receptor-deficient mice. Vet. Pathol. 34 (1997) 605-614
37. Gonzalez F.J., Fernandez-Salguero P., Lee S.S., Pineau T., and Ward J.M. Xenobiotic receptor knockout mice. Toxicol. Lett. 82-83 (1995) 117-121
38. Lahvis G.P., and Bradfield C.A. Ahr null alleles: distinctive or different?. Biochem. Pharmacol. 56 (1998) 781-787
39. Schmidt J.V., Su G.H., Reddy J.K., Simon M.C., and Bradfield C.A. Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. Proc. Natl. Acad. Sci. USA 93 (1996) 6731-6736
40. Kogevinas M. Human health effects of dioxins: cancer, reproductive and endocrine system effects. Hum. Reprod. Update 7 (2001) 331-339
41. Safe S. Molecular biology of the Ah receptor and its role in carcinogenesis. Toxicol. Lett. 120 (2001) 1-7
42. Hengstler J.G., Van der Burg B., Steinberg P., and Oesch F. Interspecies differences in cancer susceptibility and toxicity. Drug Metab. Rev. 31 (1999) 917-970
43. Casper R.F., Quesne M., Rogers I.M., Shirota T., Jolivet A., Milgrom E., and Savouret J.F. Resveratrol has antagonist activity on the aryl hydrocarbon receptor: implications for prevention of dioxin toxicity. Mol. Pharmacol. 56 (1999) 784-790
44. Jang M., Cai L., Udeani G.O., Slowing K.V., Thomas C.F., Beecher C.W., Fong H.H., Farnsworth N.R., Kinghorn A.D., Mehta R.G., Moon R.C., and Pezzuto J.M. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275 (1997) 218-220
45. Holcomb M., and Safe S. Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Lett. 82 (1994) 43-47
46. Kociba R.J., Keyes D.G., Beyer J.E., Carreon R.M., Wade C.E., Dittenber D.A., Kalnins R.P., Frauson L.E., Park C.N., Barnard S.D., Hummel R.A., and Humiston C.G. Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats. Toxicol. Appl. Pharmacol. 46 (1978) 279-303
47. McDougal A., Wilson C., and Safe S. Inhibition of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor growth by aryl hydrocarbon receptor agonists. Cancer Lett. 120 (1997) 53-63