메뉴 건너뛰기




Volumn 7, Issue 4, 2006, Pages 625-631

Global pharmacogenetics: Giving the genome to the masses

Author keywords

FDA; Genotype; Global healthcare; PGENI; Pharmacogenetics; Pharmacogenomics; Polymorphism; World Health Organization

Indexed keywords

ANESTHETIC AGENT; ANTICOAGULANT AGENT; ANTINEOPLASTIC AGENT; ARYLAMINE ACETYLTRANSFERASE; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; FLUOROURACIL; GLUCURONOSYLTRANSFERASE 1A1; GLUTATHIONE TRANSFERASE T1; IRINOTECAN; PSYCHOTROPIC AGENT; THYMIDYLATE SYNTHASE; WARFARIN;

EID: 33745165575     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/14622416.7.4.625     Document Type: Article
Times cited : (23)

References (68)
  • 1
    • 22144474788 scopus 로고    scopus 로고
    • Adverse drug event surveillance and drug withdrawals in the United States, 1969-2002: The importance of reporting suspected reactions
    • Wysowski DK, Swartz L: Adverse drug event surveillance and drug withdrawals in the United States, 1969-2002: the importance of reporting suspected reactions. Arch, Intern. Med. 165, 1363-1369 (2005).
    • (2005) Arch. Intern. Med. , vol.165 , pp. 1363-1369
    • Wysowski, D.K.1    Swartz, L.2
  • 2
    • 0035861049 scopus 로고    scopus 로고
    • Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review
    • Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W. Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review. JAMA 286, 2270-2279 (2001).
    • (2001) JAMA , vol.286 , pp. 2270-2279
    • Phillips, K.A.1    Veenstra, D.L.2    Oren, E.3    Lee, J.K.4    Sadee, W.5
  • 3
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics - Drug disposition, drug targets, and side effects
    • Evans WE, McLeod HL: Pharmacogenomics - drug disposition, drug targets, and side effects. N. Engl. J. Med. 348, 538-549 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2
  • 4
  • 5
    • 29244437163 scopus 로고    scopus 로고
    • The PPAR genes, cardiovascular disease and the emergence of PPAR pharmacogenetics
    • Cresi S: The PPAR genes, cardiovascular disease and the emergence of PPAR pharmacogenetics. Expert Opin. Pharmacother. 6, 2577-2591 (2005).
    • (2005) Expert Opin. Pharmacother. , vol.6 , pp. 2577-2591
    • Cresi, S.1
  • 6
    • 29244438809 scopus 로고    scopus 로고
    • Does pharmacogenetics have the potential to allow the individualisation of immunosuppressive drug dosing in organ transplantation?
    • MacPhee IA, Fredericks S, Holt DW: Does pharmacogenetics have the potential to allow the individualisation of immunosuppressive drug dosing in organ transplantation? Expert Opin. Pharmacother. 6, 2593-2605(2005).
    • (2005) Expert Opin. Pharmacother. , vol.6 , pp. 2593-2605
    • MacPhee, I.A.1    Fredericks, S.2    Holt, D.W.3
  • 7
    • 3042716048 scopus 로고    scopus 로고
    • The pharmacogenetics of antiretroviral therapy: A review of studies to date
    • Quirk E, McLeod H, Powderly W: The pharmacogenetics of antiretroviral therapy: a review of studies to date. Clin. Infect. Dis. 39, 98-106 (2004).
    • (2004) Clin. Infect. Dis. , vol.39 , pp. 98-106
    • Quirk, E.1    McLeod, H.2    Powderly, W.3
  • 8
    • 0037215239 scopus 로고    scopus 로고
    • Will pharmacogenetics allow better prediction of methotrexate toxicity and efficacy in patients with rheumatoid arthritis?
    • Ranganathan P, Eisen S, Yokoyama WM, McLeod HL: Will pharmacogenetics allow better prediction of methotrexate toxicity and efficacy in patients with rheumatoid arthritis? Ann. Rheum. Dis. 62, 4-9 (2003).
    • (2003) Ann. Rheum. Dis. , vol.62 , pp. 4-9
    • Ranganathan, P.1    Eisen, S.2    Yokoyama, W.M.3    McLeod, H.L.4
  • 9
    • 33644878692 scopus 로고    scopus 로고
    • Pharmacogenomics: A path to predictive medicine for schizophrenia
    • Gupta S, Jain S, Brahmachari SK, Kukreti R: Pharmacogenomics: a path to predictive medicine for schizophrenia. pharmacogenomics 7, 31-47 (2006).
    • (2006) Pharmacogenomics , vol.7 , pp. 31-47
    • Gupta, S.1    Jain, S.2    Brahmachari, S.K.3    Kukreti, R.4
  • 10
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander ES, Linton LM, Birren B et al.: Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3
  • 11
    • 0035865322 scopus 로고    scopus 로고
    • A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
    • Sachidanandam R, Weissman D, Schmidt SC et al.: A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 409, 928-933 (2001).
    • (2001) Nature , vol.409 , pp. 928-933
    • Sachidanandam, R.1    Weissman, D.2    Schmidt, S.C.3
  • 13
    • 30944455754 scopus 로고    scopus 로고
    • Predictors of virologic response to ritanavir-boosted protease inhibitors
    • Marcelin AG, Flandre P, Peytavin G, Calvez V: Predictors of virologic response to ritanavir-boosted protease inhibitors. AIDS Rev. 7, 225-232 (2005).
    • (2005) AIDS Rev. , vol.7 , pp. 225-232
    • Marcelin, A.G.1    Flandre, P.2    Peytavin, G.3    Calvez, V.4
  • 14
    • 0141567767 scopus 로고    scopus 로고
    • Molecular epidemiology of tuberculosis
    • Barnes PF, Cave MD: Molecular epidemiology of tuberculosis. N. Engl. J. Mad. 349, 1149-1156 (2003).
    • (2003) N. Engl. J. Med. , vol.349 , pp. 1149-1156
    • Barnes, P.F.1    Cave, M.D.2
  • 15
    • 25844491194 scopus 로고    scopus 로고
    • Genetic modifiers of lung disease in cystic fibrosis
    • Drumn ML, Konstan MW, Schluchter MD et al.: Genetic modifiers of lung disease in cystic fibrosis. N. Engl. J. Med. 353, 1443-1453 (2005).
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1443-1453
    • Drumn, M.L.1    Konstan, M.W.2    Schluchter, M.D.3
  • 16
    • 0037785185 scopus 로고    scopus 로고
    • Cardiovascular disease
    • Nabel EG: Cardiovascular disease. N Engl. J. Med. 349, 60-72 (2003).
    • (2003) N Engl. J. Med. , vol.349 , pp. 60-72
    • Nabel, E.G.1
  • 17
    • 6344231838 scopus 로고    scopus 로고
    • Pharmacogenetics of irinotecan toxicity
    • Marsh S, McLeod HL: Pharmacogenetics of irinotecan toxicity. Pharmacogenetics 5, 835-843 (2004).
    • (2004) Pharmacogenetics , vol.5 , pp. 835-843
    • Marsh, S.1    McLeod, H.L.2
  • 18
    • 33745141299 scopus 로고    scopus 로고
    • FDA clears Third Wave pharmacogenetic test
    • FDA clears Third Wave pharmacogenetic test. Pharmacogenomics 6, 671-672 (2005).
    • (2005) Pharmacogenomics , vol.6 , pp. 671-672
  • 19
    • 24344440879 scopus 로고    scopus 로고
    • AmpliChip CYP450 test
    • AmpliChip CYP450 test. Med. Lett. Drugs Ther. 47, 71-72 (2005).
    • (2005) Med. Lett. Drugs Ther. , vol.47 , pp. 71-72
  • 20
    • 14644400494 scopus 로고    scopus 로고
    • The impact of pharmacogenomics on postoperative nausea and vomiting: Do CYP2D6 allele copy number and polymorphisms affect the success or failure of ondansetron prophylaxis?
    • Candiotti KA, Birnbach DJ, Lubarsky DA et al.: The impact of pharmacogenomics on postoperative nausea and vomiting: do CYP2D6 allele copy number and polymorphisms affect the success or failure of ondansetron prophylaxis? Anesthesiology 102, 543-549 (2005).
    • (2005) Anesthesiology , vol.102 , pp. 543-549
    • Candiotti, K.A.1    Birnbach, D.J.2    Lubarsky, D.A.3
  • 21
    • 31544462629 scopus 로고    scopus 로고
    • Thymidylate synthase pharmacogenetics
    • Marsh S: Thymidylate synthase pharmacogenetics. Invest. New Drugs 23, 533-537 (2005).
    • (2005) Invest. New Drugs , vol.23 , pp. 533-537
    • Marsh, S.1
  • 22
  • 23
    • 20144387370 scopus 로고    scopus 로고
    • Prospective dosing of warfarin based on cytochrome P450 2C9 genotype
    • Voora D, Eby C, Linder MW et al.: Prospective dosing of warfarin based on cytochrome P450 2C9 genotype. Thromb. Haemost. 93, 700-705 (2005).
    • (2005) Thromb. Haemost. , vol.93 , pp. 700-705
    • Voora, D.1    Eby, C.2    Linder, M.W.3
  • 24
    • 0037527523 scopus 로고    scopus 로고
    • FDA issues guidance on race and ethnicity data
    • Meadows M: FDA issues guidance on race and ethnicity data. FDA Consum. 37, 36 (2003).
    • (2003) FDA Consum. , vol.37 , pp. 36
    • Meadows, M.1
  • 25
    • 0037454228 scopus 로고    scopus 로고
    • FDA guidelines on race and ethnicity: Obstacle or remedy?
    • Schultz J: FDA guidelines on race and ethnicity: obstacle or remedy? J. Natl Cancer Inst. 95, 425-426 (2003).
    • (2003) J. Natl Cancer Inst. , vol.95 , pp. 425-426
    • Schultz, J.1
  • 26
    • 14344260474 scopus 로고    scopus 로고
    • Will tomorrow's medicines work for everyone?
    • Tate SK, Goldstein DB: Will tomorrow's medicines work for everyone? Nature Genet. 36, S34-S42 (2004).
    • (2004) Nature Genet. , vol.36
    • Tate, S.K.1    Goldstein, D.B.2
  • 29
    • 0028145234 scopus 로고
    • Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5′-flanking region
    • Watanabe J, Hayashi S, Kawajiri K: Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5′-flanking region. J. Biochem. (Tokyo). 116, 321-326 (1994).
    • (1994) J. Biochem. (Tokyo). , vol.116 , pp. 321-326
    • Watanabe, J.1    Hayashi, S.2    Kawajiri, K.3
  • 30
    • 0035987174 scopus 로고    scopus 로고
    • Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1 and dihydropyrimidine debydrogenase (DPYD) in the Egyptian population
    • Hamdy SI, Hiratsuka M, Narahara K et al.: Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1 and dihydropyrimidine debydrogenase (DPYD) in the Egyptian population. Br J. Clin. Pharmacol. 53, 596-603 (2002).
    • (2002) Br J. Clin. Pharmacol. , vol.53 , pp. 596-603
    • Hamdy, S.I.1    Hiratsuka, M.2    Narahara, K.3
  • 31
    • 0027302424 scopus 로고
    • The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finnish study population
    • Hirvonen A, Husgafvel-Pursiainen K, Anttila S, Karjalainen A, Vainio H: The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finnish study population. Carcinogenesis 14, 85-88 (1993).
    • (1993) Carcinogenesis , vol.14 , pp. 85-88
    • Hirvonen, A.1    Husgafvel-Pursiainen, K.2    Anttila, S.3    Karjalainen, A.4    Vainio, H.5
  • 32
    • 1642454877 scopus 로고    scopus 로고
    • Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans
    • Mendoza-Cantu A, Castorena-Torres F, Bermudez M et al.: Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans. Cell Biochem. Fund. 22, 29-34 (2004).
    • (2004) Cell Biochem. Fund. , vol.22 , pp. 29-34
    • Mendoza-Cantu, A.1    Castorena-Torres, F.2    Bermudez, M.3
  • 33
    • 4444277920 scopus 로고    scopus 로고
    • GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population
    • Colombo J. Rossit AR, Caetano A, Borim AA, Wornrath D, Silva AE: GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population. World J. Gastroenterol. 10, 1240-1245 (2004).
    • (2004) World J. Gastroenterol. , vol.10 , pp. 1240-1245
    • Colombo, J.1    Rossit, A.R.2    Caetano, A.3    Borim, A.A.4    Wornrath, D.5    Silva, A.E.6
  • 34
    • 0035841948 scopus 로고    scopus 로고
    • CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people
    • Quinones L, Lucas D, Goday J et al.: CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people. Cancer Lett. 174, 35-44 (2001).
    • (2001) Cancer Lett. , vol.174 , pp. 35-44
    • Quinones, L.1    Lucas, D.2    Goday, J.3
  • 35
    • 0028847431 scopus 로고
    • An investigation of whether polymorphisms of cytochrome P4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a Chinese population
    • Chao YC, Young TH, Chang WK, Tang HS, Hsu CT An investigation of whether polymorphisms of cytochrome P4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a Chinese population. Hepatology 22, 1409-1414 (1995).
    • (1995) Hepatology , vol.22 , pp. 1409-1414
    • Chao, Y.C.1    Young, T.H.2    Chang, W.K.3    Tang, H.S.4    Hsu, C.T.5
  • 36
    • 0034518549 scopus 로고    scopus 로고
    • Genetic polymorphisms of biotransformation enzymes: Allele frequencies in the population of the Czech Republic
    • Sarmanova J, Tynkova L, Susova S, Gut I, Soucek P: Genetic polymorphisms of biotransformation enzymes: allele frequencies in the population of the Czech Republic. Pharmacogenetics 10, 781-788 (2000).
    • (2000) Pharmacogenetics , vol.10 , pp. 781-788
    • Sarmanova, J.1    Tynkova, L.2    Susova, S.3    Gut, I.4    Soucek, P.5
  • 37
    • 0031034845 scopus 로고    scopus 로고
    • Polymorphism in the cytochrome P450 2E1 gone and the risk of alcoholic liver disease
    • Savolainen VT, Pajarinen J, Perola M, Penttila A, Karhunen PJ: Polymorphism in the cytochrome P450 2E1 gone and the risk of alcoholic liver disease. J. Hepatol. 26, 55-61 (1997).
    • (1997) J. Hepatol. , vol.26 , pp. 55-61
    • Savolainen, V.T.1    Pajarinen, J.2    Perola, M.3    Penttila, A.4    Karhunen, P.J.5
  • 38
    • 10144256489 scopus 로고    scopus 로고
    • Cytochromes P4502E1 and P4501A1 genotypes and susceptibility to cirrhosis or upper aerodigestive tract cancer in alcoholic caucasians
    • Lucas D, Menez C, Floch F et al.: Cytochromes P4502E1 and P4501A1 genotypes and susceptibility to cirrhosis or upper aerodigestive tract cancer in alcoholic caucasians. Alcohol Clin. Exp. Res. 20, 1033-1037 (1996).
    • (1996) Alcohol Clin. Exp. Res. , vol.20 , pp. 1033-1037
    • Lucas, D.1    Menez, C.2    Floch, F.3
  • 39
    • 0035112935 scopus 로고    scopus 로고
    • Genetic determinants of alcohol addiction and metabolism: A survey in Italy
    • Pastorelli R, Bardazzi G, Saieva C et al.: Genetic determinants of alcohol addiction and metabolism: a survey in Italy. Alcohol Clin. Exp. Res. 25, 221-227 (2001).
    • (2001) Alcohol Clin. Exp. Res. , vol.25 , pp. 221-227
    • Pastorelli, R.1    Bardazzi, G.2    Saieva, C.3
  • 40
    • 0025685483 scopus 로고
    • PstI and RsaI RFLPs in complete linkage disequilibrium at the CYP2E gene
    • Watanabe J, Hayashi S, Nakachi K et al.: PstI and RsaI RFLPs in complete linkage disequilibrium at the CYP2E gene. Nucleic Acids Res. 18, 7194 (1990).
    • (1990) Nucleic Acids Res. , vol.18 , pp. 7194
    • Watanabe, J.1    Hayashi, S.2    Nakachi, K.3
  • 41
    • 0035654852 scopus 로고    scopus 로고
    • Association between polymorphisms of ethanol-metabolizing enzymes and susceptibility to alcoholic cirrhosis in a Korean male population
    • Lee HC, Lee HS, Jung SH et al.: Association between polymorphisms of ethanol-metabolizing enzymes and susceptibility to alcoholic cirrhosis in a Korean male population. J. Korean Med. Sci. 16, 745-750 (2001).
    • (2001) J. Korean Med. Sci. , vol.16 , pp. 745-750
    • Lee, H.C.1    Lee, H.S.2    Jung, S.H.3
  • 42
    • 0029793680 scopus 로고    scopus 로고
    • RsaI polymorphism at the cytochrome, P4502E1 locus and risk of hepatocellular carcinoma
    • Ladero JM, Agundez JA, Rodriguez-Lescure A, Diaz-Rubio M, Benitez J: RsaI polymorphism at the cytochrome, P4502E1 locus and risk of hepatocellular carcinoma. Gut 39, 330-333 (1996).
    • (1996) Gut , vol.39 , pp. 330-333
    • Ladero, J.M.1    Agundez, J.A.2    Rodriguez-Lescure, A.3    Diaz-Rubio, M.4    Benitez, J.5
  • 43
    • 0027401426 scopus 로고
    • Genetic polymorphism of cytochrome P4502E1 in a Swedish population. Relationship to incidence of lung cancer
    • Persson I, Johansson I, Bergling H et al.: Genetic polymorphism of cytochrome P4502E1 in a Swedish population. Relationship to incidence of lung cancer. FEBS Lett. 319, 207-211 (1993).
    • (1993) FEBS Lett. , vol.319 , pp. 207-211
    • Persson, I.1    Johansson, I.2    Bergling, H.3
  • 44
    • 3042709662 scopus 로고    scopus 로고
    • Cytochrome P4502E1 polymorphism and nasopharyngeal carcinoma development in Thailand: A correlative study
    • Kongruttanachok N, Sukdikul S, Setavarin S et al.: Cytochrome P4502E1 polymorphism and nasopharyngeal carcinoma development in Thailand: a correlative study. BMC Cancer 1, 4 (2001).
    • (2001) BMC Cancer , vol.1 , pp. 4
    • Kongruttanachok, N.1    Sukdikul, S.2    Setavarin, S.3
  • 45
    • 0035192743 scopus 로고    scopus 로고
    • Genetic polymorphism of cytochrome P450 2E1 in the Turkish population
    • Omer B, Ozbek U, Akkose A, Kilic GL Genetic polymorphism of cytochrome P450 2E1 in the Turkish population. Cell Biochem. Funct. 19, 273-275 (2001).
    • (2001) Cell Biochem. Funct. , vol.19 , pp. 273-275
    • Omer, B.1    Ozbek, U.2    Akkose, A.3    Kilic, G.L.4
  • 46
    • 0028024393 scopus 로고
    • Ethnic variation in the CYP2E1 gene: Polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese
    • Stephens EA, Taylor JA, Kaplan N et al.: Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese. Pharmacogenetics 4, 185-192 (1994).
    • (1994) Pharmacogenetics , vol.4 , pp. 185-192
    • Stephens, E.A.1    Taylor, J.A.2    Kaplan, N.3
  • 47
    • 24044497632 scopus 로고    scopus 로고
    • Genetic polymorphisms in the cytochrome P450 (1A1, 2E1), microsomal epoxide hydrolase and glutathione S-transferase M1, T1, and P1 genes, and their relationship with chronic bronchitis and relapsing pneumonia in children
    • Korytina GF, Yanbaeva DG, Babenkova LI, Etkina EI, Victorova TV: Genetic polymorphisms in the cytochrome P450 (1A1, 2E1), microsomal epoxide hydrolase and glutathione S-transferase M1, T1, and P1 genes, and their relationship with chronic bronchitis and relapsing pneumonia in children. J. Mol. Med. 83, 700-710 (2005).
    • (2005) J. Mol. Med. , vol.83 , pp. 700-710
    • Korytina, G.F.1    Yanbaeva, D.G.2    Babenkova, L.I.3    Etkina, E.I.4    Victorova, T.V.5
  • 49
    • 0037502788 scopus 로고    scopus 로고
    • Association between CYP2E1 polymorphisms and susceptibility to prostate cancer
    • Ferreira PM, Medeiros R, Vasconcelos A et al.: Association between CYP2E1 polymorphisms and susceptibility to prostate cancer. Eur. J Cancer Prev. 12, 205-211 (2003).
    • (2003) Eur. J Cancer Prev. , vol.12 , pp. 205-211
    • Ferreira, P.M.1    Medeiros, R.2    Vasconcelos, A.3
  • 50
    • 0035040258 scopus 로고    scopus 로고
    • Study of polymorphisms in the CYP2E1 gone in patients with alcoholic pancreatitis
    • Yang B, O'Reilly DA, Demaine AG, Kingsnorth AN: Study of polymorphisms in the CYP2E1 gone in patients with alcoholic pancreatitis. Alcohol 23, 91-97 (2001).
    • (2001) Alcohol , vol.23 , pp. 91-97
    • Yang, B.1    O'Reilly, D.A.2    Demaine, A.G.3    Kingsnorth, A.N.4
  • 51
    • 0036466878 scopus 로고    scopus 로고
    • Interaction between a single nucleotide polymorphism in the alcohol dehydrogenase 3 gene, alcohol consumption and oral cancer risk
    • Zavras AI, Wu T, Laskaris G et al.: Interaction between a single nucleotide polymorphism in the alcohol dehydrogenase 3 gene, alcohol consumption and oral cancer risk. Int J Cancer 97, 526-530 (2002).
    • (2002) Int J Cancer , vol.97 , pp. 526-530
    • Zavras, A.I.1    Wu, T.2    Laskaris, G.3
  • 52
    • 19444370558 scopus 로고    scopus 로고
    • CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell carcinoma
    • Gajecka M, Rydzanicz M, Jaskula-Sztul R, Kujawski M, Szyfter W, Szyfter K: CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell carcinoma. Mutat Res. 574, 112-123 (2005).
    • (2005) Mutat Res. , vol.574 , pp. 112-123
    • Gajecka, M.1    Rydzanicz, M.2    Jaskula-Sztul, R.3    Kujawski, M.4    Szyfter, W.5    Szyfter, K.6
  • 53
    • 9444252350 scopus 로고    scopus 로고
    • Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a North Indian population
    • Sobti RC, Sharma S, Joshi A, Jindal SK, Janmeja A: Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a North Indian population. Mol. Cell Biochem. 266, 1-9 (2004).
    • (2004) Mol. Cell Biochem. , vol.266 , pp. 1-9
    • Sobti, R.C.1    Sharma, S.2    Joshi, A.3    Jindal, S.K.4    Janmeja, A.5
  • 54
    • 4344682554 scopus 로고    scopus 로고
    • Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison
    • Sepehr A, Kamangar F, Abnet CC et al.: Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison. Cancer Lett. 213, 195-202 (2004).
    • (2004) Cancer Lett. , vol.213 , pp. 195-202
    • Sepehr, A.1    Kamangar, F.2    Abnet, C.C.3
  • 55
    • 0036228546 scopus 로고    scopus 로고
    • Childhood acute lymphoblastic leukemia associated with parental alcohol consumption and polymorphisms of carcinogen-metabolizing genes
    • Infante-Rivard C, Krajinovic M, Labuda D, Sinnett D: Childhood acute lymphoblastic leukemia associated with parental alcohol consumption and polymorphisms of carcinogen-metabolizing genes. Epidemiology 13, 277-281 (2002).
    • (2002) Epidemiology , vol.13 , pp. 277-281
    • Infante-Rivard, C.1    Krajinovic, M.2    Labuda, D.3    Sinnett, D.4
  • 56
    • 24044461806 scopus 로고    scopus 로고
    • Association of cytochrome P4502E1 genetic polymorphisms with squamous cell carcinoma of the oesophagus
    • Li D, Dandara C, Parker MI: Association of cytochrome P4502E1 genetic polymorphisms with squamous cell carcinoma of the oesophagus. Clin. Chem. Lab. Med. 43, 370-375 (2005).
    • (2005) Clin. Chem. Lab. Med. , vol.43 , pp. 370-375
    • Li, D.1    Dandara, C.2    Parker, M.I.3
  • 57
    • 30944432112 scopus 로고    scopus 로고
    • Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: Effects on DNA damage
    • Naccarati A, Soucek P, Stetina R et al.: Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: effects on DNA damage. Mutat. Res. 593(1-2), 22-31 (2006).
    • (2006) Mutat. Res. , vol.593 , Issue.1-2 , pp. 22-31
    • Naccarati, A.1    Soucek, P.2    Stetina, R.3
  • 58
    • 0035363947 scopus 로고    scopus 로고
    • Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas
    • Sarmanova J, Benesova K, Gut I, Nedelcheva-Kristensen V, Tynkova L, Soucek P: Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas. Hum. Mol. Genet 10, 1265-1273 (2001).
    • (2001) Hum. Mol. Genet , vol.10 , pp. 1265-1273
    • Sarmanova, J.1    Benesova, K.2    Gut, I.3    Nedelcheva-Kristensen, V.4    Tynkova, L.5    Soucek, P.6
  • 59
    • 0343619373 scopus 로고    scopus 로고
    • Colorectal cancer risk in relation to genetic polymorphism of cytochrome P4501A1, 2E1, and glutathione-S-transflerase M1 enzymes
    • Kiss I, Sandor J, Pajkos G, Bogner B, Hegedus G, Ember I: Colorectal cancer risk in relation to genetic polymorphism of cytochrome P4501A1, 2E1, and glutathione-S-transflerase M1 enzymes. Anticancer Res. 20, 519-522 (2000).
    • (2000) Anticancer Res. , vol.20 , pp. 519-522
    • Kiss, I.1    Sandor, J.2    Pajkos, G.3    Bogner, B.4    Hegedus, G.5    Ember, I.6
  • 60
    • 0031845481 scopus 로고    scopus 로고
    • Influence of genetic admixture on polymorphisms of drug-metabolizing enzymes: Analyses of mutations on NAT2 and C γ P2E1 gem in a mixed Hispanic population
    • Martinez C, Agundez JA, Olivera M et al.: Influence of genetic admixture on polymorphisms of drug-metabolizing enzymes: analyses of mutations on NAT2 and C γ P2E1 gem in a mixed Hispanic population. Clin Pharmacol. Ther. 63, 623-628 (1998).
    • (1998) Clin Pharmacol. Ther. , vol.63 , pp. 623-628
    • Martinez, C.1    Agundez, J.A.2    Olivera, M.3
  • 61
    • 5344266737 scopus 로고    scopus 로고
    • Arylamine N-acetyltransferase 2 slow acetylator polymorphisms in unrelated Iranian individuals
    • Bakayev VV, Mohammadi F, Bahadori M et al.: Arylamine N-acetyltransferase 2 slow acetylator polymorphisms in unrelated Iranian individuals. Eur J. Clin. Pharmacol 60, 467-471 (2004).
    • (2004) Eur J. Clin. Pharmacol , vol.60 , pp. 467-471
    • Bakayev, V.V.1    Mohammadi, F.2    Bahadori, M.3
  • 62
    • 0027183777 scopus 로고
    • Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a now slow-acetylator allele common in African-Americans
    • Bell DA, Taylor JA, Butler MA et al.: Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a now slow-acetylator allele common in African-Americans. Carcinogenesis 14, 1689-1692 (1993).
    • (1993) Carcinogenesis , vol.14 , pp. 1689-1692
    • Bell, D.A.1    Taylor, J.A.2    Butler, M.A.3
  • 63
    • 0027487490 scopus 로고
    • Acetylation phenotype and genotype in aboriginal leprosy patients from the north-west region of Western Australia
    • Ilett KF, Chiswell GM, Spargo RM, Platt E, Minchin RF: Acetylation phenotype and genotype in aboriginal leprosy patients from the north-west region of Western Australia. Pharmacogenetics 3, 264-269 (1993).
    • (1993) Pharmacogenetics , vol.3 , pp. 264-269
    • Ilett, K.F.1    Chiswell, G.M.2    Spargo, R.M.3    Platt, E.4    Minchin, R.F.5
  • 65
    • 0030995879 scopus 로고    scopus 로고
    • Molecular mechanisms of genetic polymorphisms of Drug metabolism
    • Meyer UA, Zanger UM: Molecular mechanisms of genetic polymorphisms of Drug metabolism. Annu. Rev. Pharmacol. Toxicol. 37, 269-296 (1997).
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 269-296
    • Meyer, U.A.1    Zanger, U.M.2
  • 66
    • 0028909978 scopus 로고
    • Slow N-acetylation genotype is a susceptibility factor in occupational and smoking-related bladder cancer
    • Risch A, Wallace DM, Bathers S, Sim E: Slow N-acetylation genotype is a susceptibility factor in occupational and smoking-related bladder cancer. Hum. Mol. Genet. 4, 231-236 (1995).
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 231-236
    • Risch, A.1    Wallace, D.M.2    Bathers, S.3    Sim, E.4
  • 67
    • 8744315598 scopus 로고    scopus 로고
    • The concept of essential medicines: Lessons for rich countries
    • Hogerzeil HV: The concept of essential medicines: lessons for rich countries. BMJ 329, 1169-1172 (2004).
    • (2004) BMJ , vol.329 , pp. 1169-1172
    • Hogerzeil, H.V.1
  • 68
    • 0038324475 scopus 로고    scopus 로고
    • 25 years of the WHO essential medicines lists: Progress and challenges
    • Laing R, Waning B, Gray A, Ford N, 't Hoen E: 25 years of the WHO essential medicines lists: progress and challenges. Lancet 361, 1723-1729 (2003).
    • (2003) Lancet , vol.361 , pp. 1723-1729
    • Laing, R.1    Waning, B.2    Gray, A.3    Ford, N.4    't Hoen, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.